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The Cytoskeletal Architecture of Trypanosoma brucei
The Journal of Parasitology, 1991The cytoskeleton of Trypanosoma brucei has been analyzed by the high-resolution technique of quick-freeze deep-etch rotary-shadowing electron microscopy. The study provides detailed structural information on the subpellicular array of microtubules, the flagellum, and the interaction of these 2 major structures of the trypanosomal cytoskeleton with each
Thomas Seebeck +2 more
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Enzymatic Targets in Trypanosoma brucei
Current Protein & Peptide Science, 2016One of the most neglected disease is the Sleeping sickness or Human African Trypanosomiasis (HAT), which is mostly restricted to poor regions of Africa. The disease is caused by parasitic infection with Trypanosoma brucei (T. brucei), and is acquired through the bite of the tsetse fly.
Marcus Tullius Scotti +3 more
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Self-fertilisation in Trypanosoma brucei
Molecular and Biochemical Parasitology, 1996We have investigated whether Trypanosoma brucei can undergo self-fertilisation. A group of 27 metacyclic clones derived from the tsetse transmission of a mixture of two genetically marked stocks was analysed and 22 clones were observed to be of non-hybrid phenotype.
Norma Buchanan +3 more
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Antioxidant defense in Trypanosoma brucei brucei
2003Two genera of protozoa belonging to the order Kinetoplastida, Trypanosoma and Leishmania, are pathogenic for mammals and cause widespread diseases of man and his livestock in developing countries. Their successful survival depends mainly on evading the hostsï immune system by penetrating and multiplying within the cells. As intracellular pathogens they
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Malleable Mitochondrion of Trypanosoma brucei
2015The importance of mitochondria for a typical aerobic eukaryotic cell is undeniable, as the list of necessary mitochondrial processes is steadily growing. Here, we summarize the current knowledge of mitochondrial biology of an early-branching parasitic protist, Trypanosoma brucei, a causative agent of serious human and cattle diseases.
Jiří Týč +15 more
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Protein isoprenylation in Trypanosoma brucei brucei [PDF]
Biochemical Society Transactions, 1996 Helen Field +3 more
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In vitro culture of Trypanosoma brucei
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1970H.J. West, Ronald A. Ward
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Uptake of α-difluoromethylornithine by Trypanosoma brucei brucei
Biochemical Pharmacology, 1986Alan J. Bitonti +3 more
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Silencing of the thioredoxin gene in Trypanosoma brucei brucei
Molecular and Biochemical Parasitology, 2002Christine Clayton +2 more
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