Results 111 to 120 of about 69,743 (296)

Integrated control of vector-borne diseases of livestock--pyrethroids: panacea or poison?

, 2003
Tick- and tsetse-borne diseases cost Africa approximately US$4-5 billion per year in livestock production-associated losses. The use of pyrethroid-treated cattle to control ticks and tsetse promises to be an increasingly important tool to counter this ...
Coleman, Paul G, Eisler, Mark C, Machila, Noreen, Morton, John F, Torr, Stephen J   +4 more
core   +1 more source

Evidence for an interplay between cell cycle progression and the initiation of differentiation between life cycle forms of African trypanosomes [PDF]

, 1994
Successful transmission of the African trypanosome between the mammalian host blood-stream and the tsetse fly vector involves dramatic alterations in the parasite's morphology and biochemistry.
Gull, K, Matthews, K R
core   +1 more source

Insight into the functional and structural relationship of ornithine decarboxylase and its mutants from Lacticaseibacillus rhamnosus

Bulletin of the Korean Chemical Society, Volume 46, Issue 7, Page 730-742, July 2025.
Structural and functional analysis of Lactaseibacillus rhamnosus ODC highlights a key residue influencing PLP binding, enzymatic activity, and crystal structure, providing insight into its catalytic mechanism. Abstract Ornithine decarboxylase (ODC) is a critical enzyme in the polyamine biosynthesis pathway that catalyzes the conversion of l‐ornithine ...
Nonvide Nicolas Adiko, Hyeon Tae Seo, Dae‐Won Ki, Jung Hee Park, Da Som Kim   +4 more
wiley   +1 more source

Trypanosoma Infection Favors Brucella Elimination via IL-12/IFNγ-Dependent Pathways

Frontiers in Immunology, 2017
This study develops an original co-infection model in mice using Brucella melitensis, the most frequent cause of human brucellosis, and Trypanosoma brucei, the agent of African trypanosomiasis. Although the immunosuppressive effects of T.
Arnaud Machelart, Margaux Van Vyve, Georges Potemberg, Aurore Demars, Carl De Trez, Hermann Giresse Tima, Gilles Vanwalleghem, Marta Romano, Carine Truyens, Jean-Jacques Letesson, Eric Muraille, Eric Muraille   +11 more
doaj   +1 more source

The Constructive Neutral Evolution of Behaviour

Ecology and Evolution, Volume 15, Issue 7, July 2025.
We explain how constructive neutral evolution (CNE) can lead to the evolution of nonfunctional behavioural complexity, highlighting a mechanism that is unknown to behavioural ecologists despite being frequently considered by molecular biologists. We summarise indirect evidence that suggests behavioural CNE has occurred and outline how the hypothesis ...
Andrew M. Catherall‐Ostler, Tanmay Dixit   +1 more
wiley   +1 more source

Ancestral sequence reconstruction of the Mic60 Mitofilin domain reveals residues supporting respiration in yeast

Protein Science, Volume 34, Issue 7, July 2025.
Abstract In eukaryotes, cellular respiration takes place in the cristae of mitochondria. The mitochondrial inner membrane protein Mic60, a core component of the mitochondrial contact site and cristae organizing system, is crucial for the organization and stabilization of crista junctions and its associated functions.
Friederike M. C. Benning, Tristan A. Bell, Tran H. Nguyen, Della Syau, Louise B. Connell, Yi‐Ting Liao, Matthew P. Keating, Margaret Coughlin, Anja E. H. Nordstrom, Maria Ericsson, Corrie J. B. daCosta, Luke H. Chao   +11 more
wiley   +1 more source

Résistance médicamenteuse d'isolats récents de Trypanosoma brucei et Trypanosoma congolense

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1988
Des études ont été menées sur des souris pour déterminer la sensibilité aux médicaments d’isolats récents de Trypanosoma brucei et Trypanosoma congolense. Chacune des onze souches de T. congolense et des cinq souches de T. brucei, toutes isolées sur des
R.A. Joshua
doaj   +1 more source

Amelioration of anaemia and organ damage by combined intraperitoneal administration of vitamins A and C to Trypanosoma brucei brucei -infected rats

, 2007
The effect of combined administration of 1000 i.u/100g body weight (bd.wt.) vitamin A and 100 mg/kg bd wt. vitamin C to Trypanosoma brucei brucei-infected rats daily for twenty-one days was investigated. The anaemia caused by T.
I. Umar, E. Ogenyi, D. Okodaso, E. Kimeng, G. Stancheva, J. Omage, S. Isah, M. Ibrahim   +7 more
semanticscholar   +1 more source

Trypanosoma brucei brucei: inhibition of glycosylation of the major variable surface coat glycoprotein by tunicamycin.

Proceedings of the National Academy of Sciences of the United States of America, 1980
Trypanosoma brucei brucei incorporates D-[3H]mannose into protein in vitro in a medium we describe here. The label appears entirely in glycoproteins with approximately 90% in the major variable surface coat glycoprotein (VSCG).
J. Strickler, C. Patton
semanticscholar   +1 more source

Aminoisothiazolamides, a new class of potent inhibitors of lysyl‐tRNA synthetase

Pest Management Science, Volume 81, Issue 7, Page 3956-3983, July 2025.
The present work covers a series of novel herbicidal lead structures that possess an aminoisothiazolamide scaffold as a structural key feature. Lysyl‐tRNA synthetase 1 (KRS1) was identified as the biochemical mode‐of‐action. Based on optimized and tailored synthetic approaches, a broader SAR study was carried out delivering some lead structures that ...
David Bernier, David M Barber, Guido Bojack, Birgit Bollenbach‐Wahl, Luke Churchman, Uwe Döller, Tyler Fahrenhorst‐Jones, Jörg Freigang, Elmar Gatzweiler, Claudia Hartfiel, Caroline Hilmi, Yoann Huet, Bernd Laber, Gudrun Lange, Stephanie Lee, Virginie Lempereur, Marc Mosrin, Thomas Müller, China M Payne, Olaf Peters, Luka Posa, Shaun Rees, Anna M Reingruber, Jullien Rey, Jörg Tiebes, Karen Tilmant, Jens Frackenpohl   +26 more
wiley   +1 more source