Background The Malanga sleeping sickness focus of the Democratic Republic of Congo has shown an epidemic evolution of disease during the last century. However, following case detection and treatment, the prevalence of the disease decreased considerably ...
Simo Gustave +8 more
doaj +1 more source
Performance of diagnostic tests for Trypanosoma brucei brucei in experimentally infected pigs. [PDF]
Ilboudo K +10 more
europepmc +1 more source
Serum lipoprotein and Trypanosoma brucei brucei interactions in vitro
Trypanosoma brucei brucei IL3201 and IL3202, which are dependent on serum high or low-density lipoproteins to multiply under axenic culture conditions, acquired lipoprotein-associated 3H-lipids without binding, accumulating or degrading apolipoproteins. Uptake by the T. b.
Vandeweerd, V., Black, Samuel J.
openaire +3 more sources
The essential roles of cytidine diphosphate-diacylglycerol synthase in bloodstream form Trypanosoma brucei [PDF]
Funded by Wellcome Trust: Senior Research Fellowship, Grant Number: 067441 and Wellcome Trust, Grant Numbers: 082596, 093228.Lipid metabolism in Trypanosoma brucei, the causative agent of African sleeping sickness, differs from its human host in several ...
Lilley, Alison C. +10 more
core +1 more source
Animal African trypanosomiasis (AAT) is a significant food security and economic burden in sub-Saharan Africa. Current AAT empirical and immunodiagnostic surveillance tools suffer from poor sensitivity and specificity, with blood sampling requiring ...
Isabel Saldanha +10 more
doaj +1 more source
Trypanocidal activity of organotin chlorides on Trypanosoma brucei-infected mice
The organotin compounds dibulyltin (DBTC) and diphenyltin dichlorides (DPTC) were tested for trypanocidal activity on a Trypanosoma brucei-infected mice model.
Shuaibu M.N. +5 more
doaj +1 more source
Effects of Synthetic Ligustrazine-Based Chalcone Derivatives on Trypanosoma brucei brucei and Leishmania spp. Promastigotes. [PDF]
Alkhaldi AAM.
europepmc +1 more source
Trypanosoma brucei brucei: Expression of drug resistance in vitro
The susceptibility of five Trypanosoma brucei brucei stocks to diminazene aceturate (Berenil) and isometamidium chloride (Samorin) was determined in vivo and in vitro. Two stocks were resistant in mice to both drugs. Differences in drug-induced growth inhibition occurred between drug-resistant and drug-sensitive stocks when trypanosome bloodstream ...
Kaminsky, R. +2 more
openaire +3 more sources
The Occurrence of Malignancy in Trypanosoma brucei brucei by Rapid Passage in Mice. [PDF]
Cai XL +6 more
europepmc +1 more source
An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei [PDF]
RNA editing in the sleeping sickness parasite Trypanosoma brucei remodels mitochondrial transcripts by the addition and deletion of uridylates as specified by guide RNAs.
Schnaufer, Achim; id_orcid +4 more
core +1 more source

