Results 111 to 120 of about 32,780 (234)

The essential neutral sphingomyelinase is involved in the trafficking of the variant surface glycoprotein in the bloodstream form of Trypanosoma brucei

, 2010
Sphingomyelin is the main sphingolipid in Trypanosoma brucei, the causative agent of African sleeping sickness. In vitro and in vivo characterization of the T.
Smith, Terry K., Young, Simon A., Young, Simon Alan   +2 more
core   +1 more source

The flagella connector of Trypanosoma brucei : an unusual mobile transmembrane junction. [PDF]

, 2004
Throughout its elongation, the new flagellum of the procyclic form of the African trypanosome Trypanosoma brucei is tethered at its tip to the lateral aspect of the old flagellum.
Sue Vaughan, Vaughan, Sue, Vaughan, S, Davidge, J, Moreira-Leite, Flavia, Keith Gull, Baines, A, Flavia Moreira-Leite, McKean, PG, Gull, K, Moreira-Leite, F, Jacqueline Davidge, Baines, Andrea, Briggs, Laura, Gull, Keith, Laura J. Briggs, McKean, Paul G., Paul G. McKean, Davidge, Jacqueline, Briggs, LJ, Andrea Baines   +20 more
core   +1 more source

Effects of Synthetic Ligustrazine-Based Chalcone Derivatives on Trypanosoma brucei brucei and Leishmania spp. Promastigotes. [PDF]

Molecules, 2023
Alkhaldi AAM.
europepmc   +1 more source

Consistent detection of Trypanosoma brucei but not T. congolense DNA in faeces of experimentally infected cattle

Scientific Reports
Animal African trypanosomiasis (AAT) is a significant food security and economic burden in sub-Saharan Africa. Current AAT empirical and immunodiagnostic surveillance tools suffer from poor sensitivity and specificity, with blood sampling requiring ...
Isabel Saldanha, Martha Betson, Christina Vrettou, Edith Paxton, James Nixon, Peter Tennant, Adrian Ritchie, Keith R. Matthews, Liam J. Morrison, Stephen J. Torr, Lucas J. Cunningham   +10 more
doaj   +1 more source

Identification of different trypanosome species in the mid-guts of tsetse flies of the Malanga (Kimpese) sleeping sickness focus of the Democratic Republic of Congo

Parasites & Vectors, 2012
Background The Malanga sleeping sickness focus of the Democratic Republic of Congo has shown an epidemic evolution of disease during the last century. However, following case detection and treatment, the prevalence of the disease decreased considerably ...
Simo Gustave, Silatsa Barberine, Flobert Njiokou, Lutumba Pascal, Mansinsa Philemon, Madinga Joule, Manzambi Emile, De Deken Reginald, Asonganyi Tazoacha   +8 more
doaj   +1 more source

High-throughput chemical screening for antivirulence developmental phenotypes in Trypanosoma brucei. [PDF]

, 2014
In the bloodstream of mammalian hosts, the sleeping sickness parasite, Trypanosoma brucei, exists as a proliferative slender form or a nonproliferative, transmissible, stumpy form.
Auer, Manfred, Ivens, A, Matthews, KR, Matthews, Keith R., Collie, I, Ivens, Alasdair, Auer, M, Gray, David, McGregor, Paula, Macgregor, Paula, Matthews, Keith R; id_orcid, Gray, David; id_orcid, Collie, Iain, Shave, S, MacGregor, P, Gray, D, Shave, Steven   +16 more
core   +1 more source

The Occurrence of Malignancy in Trypanosoma brucei brucei by Rapid Passage in Mice. [PDF]

Front Microbiol, 2021
Cai XL, Li SJ, Zhang P, Li Z, Hide G, Lai DH, Lun ZR.   +6 more
europepmc   +1 more source

Trypanocidal activity of organotin chlorides on Trypanosoma brucei-infected mice

Parasite, 2000
The organotin compounds dibulyltin (DBTC) and diphenyltin dichlorides (DPTC) were tested for trypanocidal activity on a Trypanosoma brucei-infected mice model.
Shuaibu M.N., Ameh D.A., Bonire J.J., Adaudi A.O., Ibrahim S., Nok A.J.   +5 more
doaj   +1 more source

Bloodstream form trypanosoma brucei depend upon multiple metacaspases associated with RAB11-positive endosomes [PDF]

, 2006
Trypanosoma brucei possesses five metacaspase genes. Of these, MCA2 and MCA3 are expressed only in the mammalian bloodstream form of the parasite, whereas MCA5 is expressed also in the insect procyclic form.
Coombs, G.H., Coombs, GH, Mottram, JC, Ambit, A., Helms, MJ, Ambit, A, Tetley, L., Tetley, L, Helms, Matthew J., Tetley, Laurence, Mottram, Jeremy C., Coombs, Graham H., Appleton, P., Appleton, Paul, Ambit, Audrey, Mottram, J.C., Appleton, P, Helms, M.J.   +17 more
core   +1 more source

Synthetic biology tools for engineering Goodwin oscillation in Trypanosoma brucei brucei. [PDF]

Heliyon, 2022
Borg Y, Alsford S, Pavlika V, Zaikin A, Nesbeth DN.   +4 more
europepmc   +1 more source