Background The Malanga sleeping sickness focus of the Democratic Republic of Congo has shown an epidemic evolution of disease during the last century. However, following case detection and treatment, the prevalence of the disease decreased considerably ...
Simo Gustave+8 more
doaj +1 more source
Effects of Synthetic Ligustrazine-Based Chalcone Derivatives on Trypanosoma brucei brucei and Leishmania spp. Promastigotes. [PDF]
Alkhaldi AAM.
europepmc +1 more source
Natural immunity of humans to the cattle pathogen Trypanosoma brucei brucei has been attributed to the presence in normal human serum (NHS) of lytic factors for the parasites.
J. Raper, V. Nussenzweig, S. Tomlinson
semanticscholar +1 more source
The Occurrence of Malignancy in Trypanosoma brucei brucei by Rapid Passage in Mice. [PDF]
Cai XL+6 more
europepmc +1 more source
Chalcone, Acyl Hydrazide, and Related Amides Kill Cultured Trypanosoma brucei brucei
BackgroundProtozoan parasites of the genus Trypanosoma cause disease in a wide range of mammalian hosts. Trypanosoma brucei brucei, transmitted by tsetse fly to cattle, causes a disease (Nagana) of great economic importance in parts of Africa. T.
L. Troeberg+11 more
semanticscholar +1 more source
Spatially and genetically distinct African trypanosome virulence variants defined by host interferon-g response [PDF]
We describe 2 spatially distinct foci of human African trypansomiasis in eastern Uganda. The Tororo and Soroti foci of <i>Trypanosoma brucei rhodesiense</i> infection were genetically distinct as characterized by 6 microsatellite and 1 ...
Anneli Cooper+19 more
core +1 more source
Trypanocidal activity of organotin chlorides on Trypanosoma brucei-infected mice
The organotin compounds dibulyltin (DBTC) and diphenyltin dichlorides (DPTC) were tested for trypanocidal activity on a Trypanosoma brucei-infected mice model.
Shuaibu M.N.+5 more
doaj +1 more source
Erythrocytic, Enzymatic, and Histological Markers of Oxidative Stress in Subacute and Chronic Stage Infections in Wistar Rats (Rattus norvegicus) Infected with Trypanosoma brucei brucei. [PDF]
Abubakar Z, Dabo NT.
europepmc +1 more source
On the extent and role of the small proteome in the parasitic eukaryote Trypanosoma brucei [PDF]
Background: Although technical advances in genomics and proteomics research have yielded a better understanding of the coding capacity of a genome, one major challenge remaining is the identification of all expressed proteins, especially those less than ...
Butter, F.+5 more
core +1 more source
Digyaindoleacid A (1) is one of the novel alkaloids produced by the Ghanaian Paenibacillus sp. DE2SH (GenBank Accession Number: MH091697) isolated from the mangrove rhizosphere soils of the Pterocarpus santalinoides tree growing in the wetlands of the ...
Samuel Kwain+9 more
doaj +1 more source