Results 211 to 220 of about 41,700 (258)

Cell surface localisation of GPI-anchored receptors inTrypanosoma brucei

Banerjee S, Minshall N, Cook A, Macleod O, Webb H, Higgins M, Carrington M.   +6 more
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Carnitine in Trypanosoma brucei brucei

Molecular and Biochemical Parasitology, 1982
Abstract Bloodstream and culture forms of Trypanosoma brucei brucei contain high concentrations of intracellular l -carnitine, determined enzymatically (1.46 ± 0.28 and 4.49 ± 0.34 mM , respectively), a large proportion of which is non-esterified.
Anne E. Waterhouse, Roger A. Klein, Judith M. Angus   +2 more
openaire   +3 more sources

Transketolase in Trypanosoma brucei

Molecular and Biochemical Parasitology, 2011
A single copy gene, encoding a protein highly similar to transketolase from other systems, was identified in the Trypanosoma brucei genome. The gene was expressed in E. coli and the purified protein demonstrated transketolase activity with K(m) values of 0.2mM and 0.8mM respectively for xylulose 5-phosphate and ribose 5-phosphate.
Stoffel, Sabine A., Alibu, Vincent P., Hubert, Jane, Ebikeme, Charles, Portais, Jean-Charles, Bringaud, Frédéric, Schweingruber, M. Ernst, Barrett, Michael P.   +7 more
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The cell division cycle of Trypanosoma brucei brucei: timing of event markers and cytoskeletal modulations.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 1989
We have analysed the timing and order of events occurring within the cell division cycle of Trypanosoma brucei. Cells in the earliest stages of the cell cycle possess a single copy of three major organelles: the nucleus, the kinetoplast and the flagellum.
Trevor Sherwin, K. Gull
semanticscholar   +1 more source

Transport of methionine in Trypanosoma brucei brucei

Molecular and Biochemical Parasitology, 2000
African trypanosomes live free in the bloodstream and central nervous system of mammalian hosts and also within the midgut of the tsetse fly vectors which transmit them. The parasite plasma membrane represents the interface between both hosts and parasite, and trypanosomes accumulate many essential metabolites via specific transport processes.
Marie Pierre Hasne, Michael P. Barrett
openaire   +3 more sources

Kinetics of Methionine Transport and Metabolism by Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense

Archives of Biochemistry and Biophysics, 2000
Methionine is an essential amino acid for both prokaryotic and eukaryotic organisms; however, little is known concerning its utilization in African trypanosomes, protozoa of the Trypanosoma brucei group. This study explored the Michaelis-Menten kinetic constants for transport and pool formation as well as metabolic utilization of methionine by two ...
Cyrus J. Bacchi, Nigel Yarlett, David Lloyd, Donna Rattendi, Burt Goldberg   +4 more
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Different allele frequencies in Trypanosoma brucei brucei and Trypanosoma brucei gambiense populations

Molecular and Biochemical Parasitology, 1989
Restriction fragment length polymorphism (RFLP) has been analysed in Trypanosoma brucei DNA following hybridization with different DNA probes. This polymorphism seems to be due to allelic variation, and not to variation between sequence duplicates, since the genomic environment of the probed polymorphic fragments is conserved over considerable ...
Paindavoine, Pascale, Bosseler, Françoise, Coquelet, Hélène, Pays, Etienne, Steinert, Maurice   +4 more
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Differential Effects of Trypanosoma brucei gambiense and Trypanosoma brucei brucei on Rat Macrophages

Journal of Parasitology, 2011
Mammalian immune responses to Trypanosoma brucei infection are important to control of the disease. In rats infected with T. brucei gambiense (Wellcome strain; WS) or T. brucei brucei (interleukin-tat 1.4 strain [ILS]), a marked increase in the number of macrophages in the spleen can be observed.
Hiroshi Nakagawa, Yoshihiro Ohnishi, Saburo Matsuo, Kazuhiko Nishimura, Shinji Yamasaki, Haruna Nakaya   +5 more
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Biosynthesis of Trypanothione in Trypanosoma brucei brucei

Biological Chemistry, 2003
Trypanothione [T(SH)2], the major redox mediator in pathogenic trypanosomatids, is synthetized stepwise by two distinct enzymes in Crithidia fasciculata, while in Trypanosoma cruzi a single enzyme catalyzes both steps. A full-length reading frame presumed to encode trypanothione synthetase (TryS) was obtained by PCR using DNA of T.
Ulrich Menge, Leopold Flohé, Marcelo A. Comini   +2 more
openaire   +3 more sources