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Characterization of the histones of Trypanosoma brucei brucei bloodstream forms

Acta Tropica, 1994
Five groups of histones were shown in Trypanosoma brucei brucei, displaying qualitative and quantitative differences between two stages of the parasite's life-cycle. The influence of the histones of T. b. brucei bloodstream forms on the compaction pattern of the chromatin was investigated and their extractability in diluted acids and their amino acid ...
M, Burri   +3 more
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Lipid composition of bloodstream forms of Trypanosoma brucei brucei

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1986
The qualitative and quantitative lipid composition of bloodstream forms of Trypanosoma brucei brucei S42 was compared with that of rat plasma and erythrocytes. The concentrations of lipid-bound phosphate and lipid-bound sialic acid in the trypanosomes were markedly higher than those of the rodent tissues.
M, Carroll, P, McCrorie
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Trypanosoma brucei brucei: Polycations and the release of alanine aminotransferase

Experimental Parasitology, 1972
Abstract Trypanosoma brucei brucei was exposed in vitro to the polycations protamine, poly- l -lysine and DEAE-dextran, and the effect was measured by the amount of l -alanine: 2-oxoglutarate aminotransferase (ALAT) (EC 2.6.15) released. Most was released after exposure to poly- l -lysine in a Tris buffer, less in a bicine buffer, and least in a
D G, Godfrey, A E, Taylor
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Gonadotropic dysfunction produced by Trypanosoma brucei brucei in the rat

Acta Tropica, 1990
Hormonal disorders have been frequently observed in humans and animals infected with tsetse-transmitted (African) trypanosomes. We studied the pituitary gonadal axis (plasma concentrations of testosterone, luteinizing hormone (LH), follicle stimulating hormone (FSH) and the pituitary gonadotropin (LH, FSH) concentrations) in rats as an experimental ...
M, Hublart   +5 more
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Rodent-free cyclical transmission of Trypanosoma brucei brucei

Molecular and Biochemical Parasitology, 2017
We provide a simple protocol enabling cyclical transmission of Trypanosoma brucei brucei to be performed without the need for mammals. These procedures have two advantages: they are in line with 3R principles of animal use - replace, refine, reduce - and may enable more laboratories to study the complete life cycle.
Arunasalam, Naguleswaran, Isabel, Roditi
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Pathomorphological Changes in Trypanosoma brucei brucei Infection in the Rabbit

Zentralblatt für Veterinärmedizin Reihe B, 2010
Summary In the course of Trypanosoma bracei-stabilate EATRO 1066-infection in the rabbit three stages can be distinguished: 1. An initial stage at the time of the first temperature peak, characterized by beginning lymphoid hyperplasia in the follicles, lymphoid depletion in the thymus and thymus-dependent areas of the spleen and some lymph ...
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Trypanosoma brucei brucei: Uptake and Metabolism of Pyridoxine and Pyridoxal

Experimental Parasitology, 1995
The uptake and metabolism of the B6 vitamers pyridoxine and pyridoxal by T. brucei (TREU 55) was investigated. The results show that these vitamers are taken up by simple diffusion followed by metabolic trapping. Both pyridoxine and pyridoxal were found to be metabolised to pyridoxal phosphate in whole cells.
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Uptake of α-difluoromethylornithine by Trypanosoma brucei brucei

Biochemical Pharmacology, 1986
A J, Bitonti   +3 more
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Protein isoprenylation in Trypanosoma brucei brucei

Biochemical Society Transactions, 1996
H, Field   +3 more
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Nonvariant antigens limited to bloodstream forms of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense.

The Journal of protozoology, 1985
The presence of nonvariant antigens (NVAs) limited to bloodstream forms of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense was demonstrated for the first time by immunodiffusion and immunoelectrophoresis. Noncloned and cloned populations were employed in preparation of polyclonal antisera in rabbits and of antigens to be used in the ...
D A, Beat   +4 more
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