Results 181 to 190 of about 32,780 (234)

Drawing conclusions : Confessions of a scientist who thinks better with a pencil in hand. [PDF]

EMBO Rep
Schneider A.
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A trypanosome trifecta: an independently tunable triple inducible system for genetic studies in <i>Trypanosoma brucei</i>. [PDF]

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Romprey MJ, Armstrong R, McGill P, Jenkins CM, Li JH, Klingbeil MM.   +5 more
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Carnitine in Trypanosoma brucei brucei

Molecular and Biochemical Parasitology, 1982
Abstract Bloodstream and culture forms of Trypanosoma brucei brucei contain high concentrations of intracellular l -carnitine, determined enzymatically (1.46 ± 0.28 and 4.49 ± 0.34 mM , respectively), a large proportion of which is non-esterified.
R A, Klein, J M, Angus, A E, Waterhouse
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Transport of methionine in Trypanosoma brucei brucei

Molecular and Biochemical Parasitology, 2000
African trypanosomes live free in the bloodstream and central nervous system of mammalian hosts and also within the midgut of the tsetse fly vectors which transmit them. The parasite plasma membrane represents the interface between both hosts and parasite, and trypanosomes accumulate many essential metabolites via specific transport processes.
M P, Hasne, M P, Barrett
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Biosynthesis of Trypanothione in Trypanosoma brucei brucei

Biological Chemistry, 2003
Trypanothione [T(SH)2], the major redox mediator in pathogenic trypanosomatids, is synthetized stepwise by two distinct enzymes in Crithidia fasciculata, while in Trypanosoma cruzi a single enzyme catalyzes both steps. A full-length reading frame presumed to encode trypanothione synthetase (TryS) was obtained by PCR using DNA of T.
Marcelo, Comini, Ulrich, Menge, Leopold, Flohé   +2 more
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Kinetics of Methionine Transport and Metabolism by Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense

Archives of Biochemistry and Biophysics, 2000
Methionine is an essential amino acid for both prokaryotic and eukaryotic organisms; however, little is known concerning its utilization in African trypanosomes, protozoa of the Trypanosoma brucei group. This study explored the Michaelis-Menten kinetic constants for transport and pool formation as well as metabolic utilization of methionine by two ...
B, Goldberg, D, Rattendi, D, Lloyd, N, Yarlett, C J, Bacchi   +4 more
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Differential Effects of Trypanosoma brucei gambiense and Trypanosoma brucei brucei on Rat Macrophages

Journal of Parasitology, 2011
Mammalian immune responses to Trypanosoma brucei infection are important to control of the disease. In rats infected with T. brucei gambiense (Wellcome strain; WS) or T. brucei brucei (interleukin-tat 1.4 strain [ILS]), a marked increase in the number of macrophages in the spleen can be observed.
Kazuhiko, Nishimura, Haruna, Nakaya, Hiroshi, Nakagawa, Saburo, Matsuo, Yoshihiro, Ohnishi, Shinji, Yamasaki   +5 more
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Different allele frequencies in Trypanosoma brucei brucei and Trypanosoma brucei gambiense populations

Molecular and Biochemical Parasitology, 1989
Restriction fragment length polymorphism (RFLP) has been analysed in Trypanosoma brucei DNA following hybridization with different DNA probes. This polymorphism seems to be due to allelic variation, and not to variation between sequence duplicates, since the genomic environment of the probed polymorphic fragments is conserved over considerable ...
Paindavoine, Pascale, Bosseler, Françoise, Coquelet, Hélène, Pays, Etienne, Steinert, Maurice   +4 more
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Transketolase in Trypanosoma brucei

Molecular and Biochemical Parasitology, 2011
A single copy gene, encoding a protein highly similar to transketolase from other systems, was identified in the Trypanosoma brucei genome. The gene was expressed in E. coli and the purified protein demonstrated transketolase activity with K(m) values of 0.2mM and 0.8mM respectively for xylulose 5-phosphate and ribose 5-phosphate.
Stoffel, Sabine A., Alibu, Vincent P., Hubert, Jane, Ebikeme, Charles, Portais, Jean-Charles, Bringaud, Frédéric, Schweingruber, M. Ernst, Barrett, Michael P.   +7 more
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The coatomer of Trypanosoma brucei

Molecular and Biochemical Parasitology, 2001
Coatomer is a multisubunit complex involved in trafficking of vesicles between the endoplasmatic reticulum and the Golgi apparatus. From sequence homologies, all seven subunits, alpha-, beta-, beta'-, gamma-, delta-, epsilon-, and zeta-COP, are encoded in the genome of Trypanosoma brucei.
A G, Maier, H, Webb, M, Ding, M, Bremser, M, Carrington, C, Clayton   +5 more
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