Results 101 to 110 of about 7,822 (201)

Detection of group 1 Trypanosoma brucei gambiense by loop-mediated isothermal amplification [PDF]

, 2011
Trypanosoma brucei gambiense group 1 is the major causative agent of the Gambian human African trypanosomiasis (HAT). Accurate diagnosis of Gambian HAT is still challenged by lack of precise diagnostic methods, low and fluctuating parasitemia, and ...
Njiru, Z. K., Traub, R. J., Ouma, J. O., Enyaru, J. C., Matovu, E.   +4 more
core   +1 more source

Antimicrobial Multidrug Resistance and Mechanisms of Action: An Overview

BioMed Research International, Volume 2025, Issue 1, 2025.
Antimicrobial multidrug resistance is the ability of microorganisms to withstand the effects of several antimicrobial agents, presenting a major challenge to modern healthcare systems worldwide. Although considerable research has been conducted, the molecular and evolutionary mechanisms underlying resistance are still not completely understood.
Abraham Belete Temesgen, Samuel Atalay Shiferaw, Baisakhi Banerjee   +2 more
wiley   +1 more source

Allelic segregation and independent assortment in T. brucei crosses: proof that the genetic system is Mendelian and involves meiosis [PDF]

, 2005
The genetic system on Trypanosoma brucei has been analysed by generating large numbers of independent progeny clones from two crosses, one between two cloned isolates of Trypanosoma brucei brucei and one between cloned isolates of T. b.
Annette MacLeod, Alison Tweedie, Sarah McLellan, Sonya Taylor, Anneli Cooper, Lindsay Sweeney, C. Michael R. Turner, Andy Tait, Hoare, Gibson, Tibayrenc, MacLeod, MacLeod, MacLeod, Gibson, Turner, Jenni, Sternberg, Gibson, Tait, Gibson, Le Page, Paindovoine, Hope, Su, Su, Martinelli, Culleton, Martinelli, Su, Shirley, Tait, MacLeod, El-Sayed, Hall, Benson, Gaunt, Tait, Gibson, Schweizer, Gibson, Gibson, Hassold, Hide, Van Den Abbeele   +44 more
core   +1 more source

Neglected Tropical Diseases and Female Infertility: Possible Pathophysiological Mechanisms

Journal of Tropical Medicine, Volume 2025, Issue 1, 2025.
Battling female infertility has posed a global challenge, where neglected tropical diseases (NTDs) are nonetheless a notable contributing factor. NTDs affect a variety of diseases, often of a chronic nature, which are often cited as some of the most lethal diseases operating against the most economically disadvantaged populations across the globe.
Moses Agbomhere Hamed, Olabanji Ahmed Surakat, Victor Olukayode Ekundina, Kabirat Bolajoko Jimoh, Adetomiwa Ezekiel Adeogun, Nafisat Omolola Akanji, Oluwafemi Joshua Babalola, Patrick Chukwunonso Eya, Rajib Chowdhury   +8 more
wiley   +1 more source

Silent Human Trypanosoma brucei gambiense Infections around the Old Gboko Sleeping Sickness Focus in Nigeria

Journal of Parasitology Research, 2016
Trypanosoma brucei gambiense causes Gambian trypanosomosis, a disease ravaging affected rural parts of Sub-Saharan Africa. We screened 1200 human blood samples for T. b.
Karshima Solomon Ngutor, Lawal A. Idris, Okubanjo Oluseyi Oluyinka   +2 more
doaj   +1 more source

A co-evolutionary arms race: trypanosomes shaping the human genome, humans shaping the trypanosome genome [PDF]

, 2014
<i>Trypanosoma brucei</i> is the causative agent of African sleeping sickness in humans and one of several pathogens that cause the related veterinary disease Nagana.
Capewell, Paul, Clucas, Caroline, Cooper, Anneli, MacLeod, Annette, Weir, William   +4 more
core   +1 more source

Human African Trypanosomiasis Transmission, Kinshasa, Democratic Republic of Congo

Emerging Infectious Diseases, 2006
To investigate the epidemiology of human African trypanosomiasis (sleeping sickness) in Kinshasa, Democratic Republic of Congo, 2 entomologic surveys were conducted in 2005.
Gustave Simo, Philemon Mansinsa Diabakana, Victor Kande Betu Ku Mesu, Emile Zola Manzambi, Gaelle Ollivier, Tazoacha Asonganyi, Gerard Cuny, Pascal Grébaut   +7 more
doaj   +1 more source

Epidemiology of human African trypanosomiasis

Clinical Epidemiology, 2014
Jose R Franco,1 Pere P Simarro,1 Abdoulaye Diarra,2 Jean G Jannin1 1World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland; 2World Health Organization, Inter Country Support ...
Franco JR, Simarro PP, Diarra A, Jannin JG   +3 more
doaj  

Variant Surface Glycoprotein gene repertoires in Trypanosoma brucei have diverged to become strain-specific

BMC Genomics, 2007
Background In a mammalian host, the cell surface of African trypanosomes is protected by a monolayer of a single variant surface glycoprotein (VSG). The VSG is central to antigenic variation; one VSG gene is expressed at any one time and there is a low ...
Sharma Reuben, Mott Helen, Jones Nicola G, Picozzi Kim, Hutchinson O Clyde, Welburn Susan C, Carrington Mark   +6 more
doaj   +1 more source

Transport proteins determine drug sensitivity and resistance in a protozoan parasite, Trypanosoma brucei [PDF]

, 2015
Drug resistance in pathogenic protozoa is very often caused by changes to the ‘transportome’ of the parasites. In Trypanosoma brucei, several transporters have been implicated in uptake of the main classes of drugs, diamidines and melaminophenyl ...
De Koning, Harry P., Munday, Jane C., Settimo, Luca   +2 more
core   +1 more source