Results 111 to 120 of about 7,822 (201)

Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity [PDF]

, 2017
Aquaglyceroporins (AQPs) transport water and glycerol and play important roles in drug-uptake in pathogenic trypanosomatids. For example, AQP2 in the human-infectious African trypanosome, Trypanosoma brucei gambiense, is responsible for melarsoprol and ...
A Lefurgey, A Montalvetti, AB Clarkson Jr., AP Jackson, B Bassarak, B Gourbal, B Raz, BM Bakker, C Nihei, D Promeneur, DA Evans, David Horn, E Matovu, FE Graf, FE Graf, G Priotto, J Czichos, J Robays, J Song, JC Munday, JD Bursell, JR Haanstra, K Figarella, Laura Jeacock, LL Vieira, M Chaudhuri, M Iten, M Plourde, N Baker, N Baker, Natalie Wiedemar, Nicola Baker, NL Uzcategui, NL Uzcategui, NS Carter, NW Maina, P Felgner, P Maser, P Pyana Pati, Pascal Mäser, PG Kennedy, R Brun, RW Grady, RW Grady, S Alsford, S Alsford, S Alsford, S Alsford, S Dean, S Marsiccobetre, Scott M Landfear, SK Menzies, SN Kibona, T Shiba, T Zeuthen, U Bronner, U Wille, Y Yabu   +57 more
core   +4 more sources

Enzyme variation in Trypanosoma brucei spp. I. Evidence for the sub-speciation of Trypanosoma brucei gambiense

Parasitology, 1984
SummaryThree groups of stocks of Trypanosoma brucei ssp, defined by the criteria of host, human serum resistance and place of isolation as T. b. gambiense, T. b. brucei (Nigeria) and T. b. brucei/rhodesiense (non-gambiense, Uganda) were screened for electrophoretic variation at 20 enzyme loci.
A, Tait, E A, Babiker, D, Le Ray
openaire   +2 more sources

Strategies for Trypanosoma brucei gambiense elimination [PDF]

The Lancet Global Health, 2017
Pandey, Abhishek, Galvani, Alison
openaire   +2 more sources

Analysis of the proteome and the secretome of animal trypanosomes : a standardized analytical method to look for new molecular targets [PDF]

, 2007
The causative agents of animal trypanosomosis are various species of protozoan parasites belonging to the genus Trypanosoma, among which T. congolense and T. evansi are the major pathogenic species. The extra cellular position of the trypanosomes implies
Bengaly, Zakaria, Boulangé, Alain, Brizard, Jean-Paul, Courtois, Pierrette, Cuny, Gérard, Daulouède, Sylvie, Frutos, Roger, Grébaut, Pascal, Holzmuller, Philippe, Peltier, Jean-Benoît, Vincendeau, Philippe   +10 more
core  

An Overview of Trypanosoma brucei Infections: An Intense Host–Parasite Interaction [PDF]

, 2016
Trypanosoma brucei rhodesiense and T. brucei gambiense, the causative agents of Human African Trypanosomiasis, are transmitted by tsetse flies. Within the vector, the parasite undergoes through transformations that prepares it to infect the human host ...
Alicia Ponte-Sucre
core   +1 more source

Nanobodies as tools to understand, diagnose, and treat African trypanosomiasis [PDF]

, 2017
African trypanosomes are strictly extracellular protozoan parasites that cause diseases in humans and livestock and significantly affect the economic development of sub-Saharan Africa.
Caljon, Guy, De Baetselier, Patrick, Magez, Stefan, Stijlemans, Benoit, Van Den Abbeele, Jan, Van Ginderachter, Jo A   +5 more
core   +1 more source

Immunoinformatic design of a putative multi-epitope vaccine candidate against Trypanosoma brucei gambiense. [PDF]

Comput Struct Biotechnol J, 2022
Danazumi AU, Iliyasu Gital S, Idris S, Bs Dibba L, Balogun EO, Górna MW.   +5 more
europepmc   +1 more source

Modelling host- Trypanosoma brucei gambiense interactions in vitro using human induced pluripotent stem cell-derived cortical brain organoids. [PDF]

F1000Res, 2023
Chandrasegaran P, Nabilla Lestari A, Sinton MC, Gopalakrishnan J, Quintana JF.   +4 more
europepmc   +1 more source

Metabolomics guides rational development of a simplified cell culture medium for drug screening against Trypanosoma brucei [PDF]

, 2013
n vitro culture methods underpin many experimental approaches to biology and drug discovery. The modification of established cell culture methods to make them more biologically relevant or to optimize growth is traditionally a laborious task.
Alsford, Alsford, Baltz, Barrett, Berger, Berger, Bitonti, Bowling, Bradley, Breitling, Brun, Brunda Nijagal, Creek, Creek, Creek, Darren J. Creek, de Koning, Dong-Hyun Kim, Drexler, Duszenko, Duszenko, Federico Rojas, Geary, Haanstra, Hasne, Hirumi, Hirumi, Hirumi, Jacobs, Keith R. Matthews, Kuettel, Kwon, Lanteri, Lanteri, Mashego, Michael P. Barrett, Mäser, Räz, Saunders, Scalbert, Scheltema, Scheltema, Seed, Sienkiewicz, Smith, Sumner, Sykes, t'Kindt, Tautenhahn, Vincent, Wang, Ward, Wilson, Winder, Wishart, Wu, Zaboikin, Zang, Zhang   +58 more
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Control of sleeping sickness due to Trypanosoma brucei gambiense.

Bulletin of the World Health Organization, 1983
Sleeping sickness due to Trypanosoma brucei gambiense is endemic in 23 African countries and an estimated 45 million people are exposed to infection. The relatively low incidence of the disease (about 10 000 new cases each year) is mainly a result of 50 years of regular medical surveillance and treatment in combination with tsetse control where ...
openaire   +2 more sources