Results 91 to 100 of about 4,641 (209)

Human African Trypanosomiasis in Emigrant Returning to China from Gabon, 2017

Emerging Infectious Diseases, 2018
Human African trypanosomiasis is endemic to parts of sub-Saharan Africa and should be considered in the differential diagnosis of patients who have visited or lived in Africa.
Xinyu Wang, Qiaoling Ruan, Wen-Hong Zhang, Jianfei Gu, Yiyi Qian, Muxin Chen, Qin Liu, Qing Lu, Wenhong Zhang   +8 more
doaj   +1 more source

Improvement of colony management in insect mass‐rearing for sterile insect technique applications

Insect Science, Volume 32, Issue 5, Page 1476-1494, October 2025.
Abstract Sterile Insect Technique (SIT) applications against major insect pests and disease vectors rely on the cost‐effective production of high‐quality sterile males. This largely depends on the optimal management of target pest colonies by maximizing the benefits provided by a genetically rich and pathogen‐free mother colony, the presence of ...
Adly M.M. Abd‐Alla, Anne Geiger, David Haymer, Salvador Herrero, Johannes, A. Jehle, Fathiya Khamis, Pablo Liedo, Anna R. Malacrida, Flobert Njiokou, Thiago Mastrangelo, Soumaïla Pagabeleguem, Edwin M. Ramırez‐Santos, Vera I.D. Ros, Diego F. Segura, George Tsiamis, Brian L. Weiss   +16 more
wiley   +1 more source

Isolation and analysis of the genetic diversity of repertoires of VSG expression site containing telomeres from Trypanosoma brucei gambiense, T. b. brucei and T. equiperdum

BMC Genomics, 2008
Background African trypanosomes (including Trypanosoma brucei) are unicellular parasites which multiply in the mammalian bloodstream. T. brucei has about twenty telomeric bloodstream form Variant Surface Glycoprotein (VSG) expression sites (BESs), of ...
Becker Marion, Kurioka Ayako, Taylor Jesse E, Young Rosanna, Louis Edward J, Rudenko Gloria   +5 more
doaj   +1 more source

New tsetse (Glossina fuscipes fuscipes) genomes generated from wild and laboratory‐reared specimens

Insect Science, Volume 32, Issue 5, Page 1588-1596, October 2025.
Abstract Tsetse (Glossina spp.) are vectors of African trypanosomes that cause devastating human and animal African trypanosomiases. While much of the research to better understand tsetse genetics and physiology relies on colony‐reared flies, these flies may not represent the genetic diversity found in natural wild populations due to their long‐term ...
Daniel J. Bruzzese, Brian L. Weiss, Richard Echodu, Paul O. Mireji, Adly M.M Abd‐Alla, Serap Aksoy   +5 more
wiley   +1 more source

From sentinel surveillance for sleeping sickness treatment failure to the development of a pharmacovigilance approach [PDF]

, 2011
In the late 1990’s a disturbing trend of geographically distinct melarsoprol treatment failures accompanied a dramatic resurgence of Human African Trypanosomiasis.
Dahl, Benjamin Arthur
core   +1 more source

Recherche du réservoir animal sauvage de Trypanosoma sp chez les mammifères de N'Djili-Brasseries à  Kinshasa en République Démocratique du Congo (RDC)

Revue Marocaine des Sciences Agronomiques et Vétérinaires, 2017
Durant 6 mois, 201 spécimens de mammifères sauvages représentant 7 espèces réparties en 6 genres, 4 familles et 3 ordres, dont 2 Genetta angolensis, 3 Nandinia binotata, 10 Galagoides demidoff, 35 Protoxerus strangeri, 73 Funisciurus congicus, 15 Rattus
Matthieu Willy KABAMBA MWAMBA, Curé Georges TSHILENGE MBUYI, J. MALEKANI   +2 more
doaj  

African Trypanosomiasis Gambiense, Italy

Emerging Infectious Diseases, 2005
African trypanosomiasis caused by Trypanosoma brucei gambiense has not been reported in Italy. We report 2 cases diagnosed in the summer of 2004. Theses cases suggest an increased risk for expatriates working in trypanosomiasis-endemic countries.
Zeno Bisoffi, Anna Beltrame, Geraldo Monteiro, Alessandra Arzese, Stefania Marocco, Giada Rorato, Mariella Anselmi, Pierluigi Viale   +7 more
doaj   +1 more source

In Vitro Leishmanicidal Efficacy of Synthesized Arylidene Analogues of Glitazone

Drug Development Research, Volume 86, Issue 5, August 2025.
ABSTRACT Diabetes is a fast‐growing health issue in low‐ and middle‐income countries, with ~80% of diabetics living in the tropics and sub‐tropics. It is a deadly condition claiming the lives of millions of individuals annually, with no therapeutic treatment available to date. The management of diabetes is thus limited to symptomatic relief by glycemic
Janine Aucamp, Helena D. Janse van Rensburg, Simon S. Mnyakeni‐Moleele, Keisuke Suganuma, David D. N'Da   +4 more
wiley   +1 more source

Nifurtimox plus eflornithine for late-stage sleeping sickness in Uganda: A case series [PDF]

, 2007
Background: We report efficacy and safety outcomes from a prospective case series of 31 late-stage T. b. gambiense sleeping sickness (Human African Trypanosomiasis, HAT) patients treated with a combination of nifurtimox and eflornithine (N+ E) in Yumbe ...
Thomas, F, Legros, Dominique, Francesco Checchi, Patrice Piola, Thomas Florence, Ayikoru Harriet, Gerardo Priotto, Piola, P, Ayikoru, H, Piola, Patrice, Ayikoru, Harriet, Checchi Francesco, Legros, D, Thomas, Florence, Priotto Gerardo, Checchi, F, Priotto, Gerardo, Florence Thomas, Priotto, G, Checchi, Francesco, Legros Dominique, Dominique Legros, Harriet Ayikoru, Piola Patrice   +23 more
core   +1 more source

Overproduction and Characterization of Recombinant Soluble Trypanosoma brucei Phospholipase A2

Engineering in Life Sciences, Volume 25, Issue 3, March 2025.
ABSTRACT Trypanosoma brucei phospholipase A2 (TbPLA2) is a validated drug target but the difficulty in expressing its soluble recombinant protein has limited its exploitation for drug and vaccine development for African and American trypanosomiases. We utilized recombinant deoxyribonucleic acid (DNA) technology approaches to express soluble TbPLA2 in ...
Oluwafemi Abiodun Adepoju, Daniel Quinnell, Harshverdhan Sirohi, Emmanuel Amlabu, Abdullahi Balarabe Sallau, Abdulrazak Ibrahim, Sunday Ene‐Ojo Atawodi, Mohammed Nasiru Shuaibu, Geoffrey Chang, Emmanuel Oluwadare Balogun   +9 more
wiley   +1 more source