Results 81 to 90 of about 4,641 (209)

Health Benefits and Therapeutic Potential of Quercetin

open access: yesJournal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Quercetin, a polyphenolic compound prevalent in many fruits, vegetables, and other dietary sources, has attracted considerable interest due to its extensive health benefits. This review examines its diverse biological properties, particularly its antioxidant and anti‐inflammatory effects. The study integrates recent scientific findings to elucidate the
Mahendra Aryal, Kim Wei Chan
wiley   +1 more source

Accuracy of five algorithms to diagnose gambiense human African trypanosomiasis.

open access: yes, 2011
Algorithms to diagnose gambiense human African trypanosomiasis (HAT, sleeping sickness) are often complex due to the unsatisfactory sensitivity and/or specificity of available tests, and typically include a screening (serological), confirmation ...
Francesco Checchi   +19 more
core   +1 more source

Phase II evaluation of sensitivity and specificity of PCR and NASBA followed by oligochromatography for diagnosis of human African trypanosomiasis in clinical samples from D.R. Congo and Uganda. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2010
BACKGROUND: The polymerase chain reaction (PCR) and nucleic acid sequence-based amplification (NASBA) have been recently modified by coupling to oligochromatography (OC) for easy and fast visualisation of products.
Enock Matovu   +8 more
doaj   +1 more source

Impact of long‐term mass‐rearing on the genetic structure of tsetse fly Glossina palpalis gambiensis colonies

open access: yesInsect Science, Volume 32, Issue 5, Page 1575-1587, October 2025.
Abstract Tsetse flies are the sole cyclic vectors of African trypanosomes, which cause human and animal African trypanosomiases in Africa. Tsetse fly control remains a promising option for disease management. The sterile insect technique (SIT) stands as an environmentally friendly tool to control tsetse populations.
Kiswend‐sida M. Dera   +9 more
wiley   +1 more source

Using molecular data for epidemiological inference: assessing the prevalence of Trypanosoma brucei rhodesiense in Tsetse in Serengeti, Tanzania [PDF]

open access: yes, 2012
Background: Measuring the prevalence of transmissible Trypanosoma brucei rhodesiense in tsetse populations is essential for understanding transmission dynamics, assessing human disease risk and monitoring spatio-temporal trends and the impact of control ...
Auty, Harriet K.   +26 more
core   +1 more source

Search for the wild animal reservoir of Trypanosoma sp in mammals of N’Djili-Brasseries (Kinshasa, Democratic Republic of Congo)

open access: yesRevue Marocaine des Sciences Agronomiques et Vétérinaires, 2018
During 6 months, 201 specimens of wild mammals representing 7 species divided into 6 genera, 4 families and 3 orders, of which 2 Genetta angolensis, 3 Nandinia binotata, 10 Galagoides demidoff, 35 Protoxerus strangeri, 73 Funisciurus congicus, 15 Rattus ...
M.W. Kabamba Mwamba   +2 more
doaj  

Mathematical modelling of polyamine metabolism in bloodstream-form trypanosoma brucei: An application to drug target identification [PDF]

open access: yes, 2013
© 2013 Gu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Desmond J Higham   +16 more
core   +1 more source

Identification of Peptide Mimotopes of Trypanosoma brucei gambiense Variant Surface Glycoproteins

open access: yesPLoS Neglected Tropical Diseases, 2011
The current antibody detection tests for the diagnosis of gambiense human African trypanosomiasis (HAT) are based on native variant surface glycoproteins (VSGs) of Trypanosoma brucei (T.b.) gambiense. These native VSGs are difficult to produce, and contain non-specific epitopes that may cause cross-reactions. We aimed to identify mimotopic peptides for
Van Nieuwenhove, Liesbeth Carolien   +7 more
openaire   +5 more sources

Spiroplasma infection in colonized Glossina fuscipes fuscipes: impact on mass rearing and the sterile insect technique

open access: yesInsect Science, Volume 32, Issue 5, Page 1761-1776, October 2025.
Abstract Tsetse flies (Glossina spp.) can vector the parasites (Trypanosoma spp.) that cause the socioeconomically devastating neglected tropical diseases human and animal African trypanosomoses. In addition to this parasite, tsetse can harbor four genera of endosymbiotic bacteria, including Wigglesworthia, Sodalis, Wolbachia, and Spiroplasma, which ...
Kiswend‐sida M. Dera   +14 more
wiley   +1 more source

Computer-aided identification of Trypanosoma brucei uridine diphosphate galactose 4'-epimerase inhibitors : toward the development of novel therapies for African sleeping sickness [PDF]

open access: yes, 2010
Trypanosoma brucei, the causative agent of human African trypanosomiasis, affects tens of thousands of sub-Saharan Africans. As current therapeutics are inadequate due to toxic side effects, drug resistance, and limited effectiveness, novel therapies are
Michael A. J. Ferguson   +8 more
core   +1 more source

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