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Gonadotropic axis and Trypanosoma brucei gambiense infection.
Annales de la Societe belge de medecine tropicale, 1989A gonad endocrine survey on 46 Congolese patients (15 women and 31 men) with parasitologically confirmed trypanosomiasis found amenorrhoea in 60% of the women and impotence in 70% of the men. The basic gonad endocrine examination showed a decrease in oestradiol levels in about 65% of the women. Both amenorrhoea and low oestrogen levels were observed in
A, Boersma +6 more
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The role of immunoglobulins in immunity to Trypanosoma brucei gambiense
International Journal for Parasitology, 1977Abstract The effects of IgM and IgG antibody molecules were compared on a weight basis by both agglutination and in vitro protection tests. It was shown that IgM is a better agglutinating antibody and in the presence of complement is also a better neutralizing antibody.
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The American Society of Tropical Medicine and Hygiene, 1987
Tyrosine aminotransferase (TAT), glutamic-pyruvic transaminase (GPT), glutamic-oxaloacetic transaminase (GOT), and alkaline phosphatase (ALP) were measured in the serum and livers of Microtus montanus infected with Trypanosoma brucei gambiense. Only liver TAT and serum ALP showed significant changes.
J R, Seed, J, Sechelski, J E, Hall
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Tyrosine aminotransferase (TAT), glutamic-pyruvic transaminase (GPT), glutamic-oxaloacetic transaminase (GOT), and alkaline phosphatase (ALP) were measured in the serum and livers of Microtus montanus infected with Trypanosoma brucei gambiense. Only liver TAT and serum ALP showed significant changes.
J R, Seed, J, Sechelski, J E, Hall
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Maintenance of B cells during chronic murine Trypanosoma brucei gambiense infection
Parasite Immunology, 2016SummaryAfrican trypanosomosis is a debilitating parasitic disease occurring in large parts of sub‐Saharan Africa. Trypanosoma brucei gambiense accounts for 98% of the reported HAT infections and causes a chronic, gradually progressing disease. Multiple experimental murine models for trypanosomosis have demonstrated inflammation‐dependent apoptosis of ...
Cnops, Jennifer +7 more
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1995
Trypanosoma brucei gambiense and T. b. rhodesiense, two subspecies of hemoflagellates, are responsible for a disease commonly referred to as African trypanosomiasis. Both of these organisms are transmitted by the bite of various species of the tsetse fly of the genus Glossina (see Chap. 38) and infect human populations throughout Equatorial Africa.
Dickson D. Despommier +2 more
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Trypanosoma brucei gambiense and T. b. rhodesiense, two subspecies of hemoflagellates, are responsible for a disease commonly referred to as African trypanosomiasis. Both of these organisms are transmitted by the bite of various species of the tsetse fly of the genus Glossina (see Chap. 38) and infect human populations throughout Equatorial Africa.
Dickson D. Despommier +2 more
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Tissue Alterations in Microtus montanus Chronically Infected with Trypanosoma brucei gambiense
The Journal of Parasitology, 1991Changes in liver, spleen, kidneys, heart, and brain are reported for Microtus montanus chronically infected with Trypanosoma brucei gambiense. An increase in body weight of infected animals was attributable to a significant increase in total mass of spleen, liver and kidney.
T O, Frommel, Y, Fujikura, J R, Seed
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A receptor-like flagellar pocket glycoprotein specific to Trypanosoma brucei gambiense
Molecular and Biochemical Parasitology, 2001Trypanosoma brucei gambiense and T. b. rhodesiense are protozoan parasites causing sleeping sickness in humans due to their resistance to lysis by normal human serum (NHS). Based on the observation that the resistance gene of T. b. rhodesiense encodes a truncated form of the variant specific glycoprotein (VSG), we cloned a similar gene in T.
Berberof, M +2 more
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Long term exposure of Trypanosoma brucei gambiense to pentamidine in vitro
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994In order to study the sensitivity in vitro of Trypanosoma brucei gambiense to pentamidine, 5 x 10(4) parasites were exposed to 0, 0.1, 1.0, 2.0, 10, 100, 1000 and 10,000 micrograms/L of pentamidine isethionate for up to 10 d. The viability of parasites was determined each day by microscopy.
T W, Miézan +4 more
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Effects of Heparin Administration on Trypanosoma brucei gambiense Infection in Rats
Journal of Parasitology, 2005We examined whether heparin administration influences in vivo trypanosome proliferation in infected rats. Administration of heparin every 8 hr via cardiac catheter inhibited growth of Trypanosoma brucei gambiense and prolonged survival of treated rats.
Kazuhiko, Nishimura +4 more
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Freeze‐Fracture Study of the Bloodstream Form of Trypanosoma brucei gambiense
The Journal of Protozoology, 1990ABSTRACTThe ultrastructure of Trypanosoma brucei gambiense was investigated by the freeze‐fracture method. Three different regions of the continuous plasma membrane; cell body proper, flagellar pocket, and flagellum were compared in density and distribution of the intramembranous particles (IMP's).
H, Yoshikawa +4 more
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