Results 201 to 210 of about 22,324 (235)

Unexpected discovery of Trypanosoma brucei gambiense on CSF in a western country: About a case

Lou-Ann Francois, Laurent Bret, Jonathan Wong So, C. Gubavu, F. Touafek, Morgane Vinsonneau, Khaoula Kochbati, Véronique Avettand-Fènoël, Clémence Guillaume, Étienne Carbonnelle, Jérôme Guinard, Gilbert Mchantaf   +11 more
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Metabolomics study of 3-O-p-(Z/E)-coumaroyltormentic acid-treated Trypanosoma brucei brucei. [PDF]

Int J Parasitol Drugs Drug Resist
Mamede L, Fall F, Vast M, Hughes K, Martelli G, Caligiore F, Govaerts B, Michels PAM, Frédérich M, Quetin-Leclercq J.   +9 more
europepmc   +1 more source

Carmaphycin B-Based Proteasome Inhibitors to Treat Human African Trypanosomiasis: Structure-Activity Relationship and <i>In Vivo</i> Efficacy. [PDF]

ACS Infect Dis
Liu LJ, Francisco KR, Sun YU, Serafim MSM, Amarasinghe DK, Teixeira TR, Lucero B, Kronenberger T, Elsayed W, Elwakeel H, Al-Hindy M, Almaliti J, Gerwick WH, O'Donoghue AJ, Caffrey CR.   +14 more
europepmc   +1 more source

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Mechanism of Trypanosoma brucei gambiense resistance to human serum

Nature, 2013
The African parasite Trypanosoma brucei gambiense accounts for 97% of human sleeping sickness cases. T. b. gambiense resists the specific human innate immunity acting against several other tsetse-fly-transmitted trypanosome species such as T. b. brucei, the causative agent of nagana disease in cattle.
Pierrick Uzureau, Sophie Uzureau, L. Lecordier, Frédéric Fontaine, P. Tebabi, F. Homblé, A. Grélard, Vanessa Zhendre, D. Nolan, L. Lins, J. Crowet, A. Pays, Cécile Felu, P. Poelvoorde, Benoît Vanhollebeke, S. Moestrup, Jeppe Lyngsø, J. S. Pedersen, J. Mottram, E. Dufourc, D. Perez-Morga, E. Pays   +21 more
semanticscholar   +5 more sources

Purine metabolism in Trypanosoma brucei gambiense

Biochimica et Biophysica Acta (BBA) - General Subjects, 1982
Abstract The procyclic forms of Trypanosoma brucei gambiense do not incorporate glycine or serine into ribonucleotides. Although de novo purine synthesis does not occur, all purine bases and ribonucleotides are interconverted, indicating the presence of active salvage pathways. Guanine is actively deaminated to xanthine by guanase activity.
Randolph L. Berens, Wallace R. Fish, J. Joseph Marr   +2 more
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Different allele frequencies in Trypanosoma brucei brucei and Trypanosoma brucei gambiense populations

Molecular and Biochemical Parasitology, 1989
Restriction fragment length polymorphism (RFLP) has been analysed in Trypanosoma brucei DNA following hybridization with different DNA probes. This polymorphism seems to be due to allelic variation, and not to variation between sequence duplicates, since the genomic environment of the probed polymorphic fragments is conserved over considerable ...
Paindavoine, Pascale, Bosseler, Françoise, Coquelet, Hélène, Pays, Etienne, Steinert, Maurice   +4 more
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Differential Effects of Trypanosoma brucei gambiense and Trypanosoma brucei brucei on Rat Macrophages

Journal of Parasitology, 2011
Mammalian immune responses to Trypanosoma brucei infection are important to control of the disease. In rats infected with T. brucei gambiense (Wellcome strain; WS) or T. brucei brucei (interleukin-tat 1.4 strain [ILS]), a marked increase in the number of macrophages in the spleen can be observed.
Hiroshi Nakagawa, Yoshihiro Ohnishi, Saburo Matsuo, Kazuhiko Nishimura, Shinji Yamasaki, Haruna Nakaya   +5 more
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Nitric oxide-mediated cytostatic activity on Trypanosoma brucei gambiense and Trypanosoma brucei brucei

Experimental Parasitology, 1992
Macrophages collected from BCG-infected mice or exposed in vitro to interferon-gamma plus lipopolysaccharide developed a cytostatic activity on Trypanosoma brucei gambiense and Trypanosoma brucei brucei. This trypanostatic activity of activated macrophages was inhibited by addition of N-monomethyl-L-arginine, an inhibitor of the L-arginine-nitric oxide
Bernard Veyret, Jean Loup Lemesre, Marie Laure Dardé, Bernard Bouteille, P. Vincendeau, Sylvie Daulouède   +5 more
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"Trypanosoma brucei gambiense" : cerebral immunopathology in mice

Acta tropica, 1982
Ninety outbred white adult female mice were infected with Trypanosoma brucei gambiense (GUMS 2, alias LUMP 1237) originating from a Zairian patient and known to produce a low parasitaemia in rodents. The development of cerebral trypanosomiasis was independent upon the number of parasites inoculated per mouse.
A A, Poltera, A, Hochmann, P H, Lambert
openaire   +2 more sources