Results 141 to 150 of about 59,489 (194)

Development and pilot application of a point-of-need molecular xenomonitoring protocol for tsetse (Glossina sp.) in a low-resource setting. [PDF]

PLoS Negl Trop Dis
Saldanha I, Aziku E, Trima AT, Drapari V, Garrod G, Ombanya H, Tirados I, Betson M, Mugenyi A, Dunkley S, Torr SJ, Hope A, Cunningham LJ.   +12 more
europepmc   +1 more source

Sensitivity and specificity of HAT Bioline Abbott^® 2.0 and HAT Sero K-Set CORIS^® 2.0 for human African trypanosomiasis in the Kasai-Oriental province, Democratic Republic of the Congo: a retrospective diagnostic accuracy study. [PDF]

Parasit Vectors
Kayembe S, Vulu F, Mpanya A, Kakiese E, Kalonji R, Fataki O, Kuispond NS, Ngoyi DM.   +7 more
europepmc   +1 more source

Germline-targeted baboon apolipoprotein L-1 protects mice against African trypanosomes. [PDF]

Proc Natl Acad Sci U S A
Fresard S, Pangburn SJ, Leiss K, Boodwa-Ko D, Kovacsics D, Schoenherr CJ, Rabinowitz JS, Economides AN, Li L, Qiu W, Gonzalez-Baradat B, Rosa A, Thomson R, Raper J, Verdi J.   +14 more
europepmc   +1 more source

Harnessing nature: a systematic exploration of <i>in vitro</i> antileishmanial and antihuman African trypanosomal properties in traditional medicinal plants and their active principles. [PDF]

Pharm Biol
Ahmed QU, Mat Nasir NA, Begum T, Helal Uddin ABM, Parveen H, Albalawi MO, Ali Khan Khattak MM, Azmi SNH, Sarian MN, Kurniawati AD, Zakaria ZA.   +10 more
europepmc   +1 more source

Decolonising Parasitology: The Case of Trypanosoma brucei rhodesiense [PDF]

Trends in Parasitology, 2021
Trypanosoma brucei rhodesiense was named after Rhodesia which, in turn, was named after the British imperialist and white supremacist Cecil Rhodes. In the light of the Black Lives Matter movement and contemporary consciousness of postcolonial legacy, it seems opportune to reconsider the subspecies name. Pros and cons of renaming T. b.
Dietmar Steverding, Kevin M. Tyler
exaly   +4 more sources

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Unravelling the origins of Trypanosoma brucei rhodesiense

Trends in Parasitology, 2002
Sleeping sickness in East Africa is caused by Trypanosoma brucei rhodesiense, which occurs in discrete foci of disease throughout the distribution range of its tsetse vector. Outbreaks of the disease can be traced to wild game and, in particular, cattle. Both wild game and cattle harbour the human infective T.
Richard Reithinger
exaly   +3 more sources

Loop-Mediated Isothermal Amplification (LAMP) Method for Rapid Detection of Trypanosoma brucei rhodesiense [PDF]

PLoS Neglected Tropical Diseases, 2008
Loop-mediated isothermal amplification (LAMP) of DNA is a novel technique that rapidly amplifies target DNA under isothermal conditions. In the present study, a LAMP test was designed from the serum resistance-associated (SRA) gene of Trypanosoma brucei ...
Joseph Mathu Ndung'U
exaly   +1 more source

Synthesis and evaluation of tetrahydroisoquinoline derivatives against Trypanosoma brucei rhodesiense

European Journal of Medicinal Chemistry, 2021
Human African Trypanosomiasis (HAT) is a neglected tropical disease caused by the parasitic protozoan Trypanosoma brucei (T. b.), and affects communities in sub-Saharan Africa. Previously, analogues of a tetrahydroisoquinoline scaffold were reported as having in vitro activity (IC50 = 0.25-70.5 μM) against T. b. rhodesiense. In this study the synthesis
Danica R. Cullen, Ashlee Gallagher, Caitlin L. Duncan, Jutharat Pengon, Roonglawan Rattanajak, Jason Chaplin, Hendra Gunosewoyo, Sumalee Kamchonwongpaisan, Alan Payne, Mauro Mocerino   +9 more
openaire   +2 more sources

Kinetics of Methionine Transport and Metabolism by Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense

Archives of Biochemistry and Biophysics, 2000
Methionine is an essential amino acid for both prokaryotic and eukaryotic organisms; however, little is known concerning its utilization in African trypanosomes, protozoa of the Trypanosoma brucei group. This study explored the Michaelis-Menten kinetic constants for transport and pool formation as well as metabolic utilization of methionine by two ...
B, Goldberg, D, Rattendi, D, Lloyd, N, Yarlett, C J, Bacchi   +4 more
openaire   +2 more sources

The effect of spiroarsoranes on Trypanosoma brucei brucei and T. b. rhodesiense

Parasitology Research, 1996
Topical application and intraperitoneal administration of spiroarsoranes were carried out to cure central nervous system (CNS) trypanosomiasis in the chronic Trypanosoma brucei GVR 35 mouse model. Topical application appeared more efficient than intraperitoneal injection. The periods of aparasitaemia after treatment were longer but none of the mice was
P M, Loiseau, F W, Jennings, P, Lubert, J G, Wolf   +3 more
openaire   +2 more sources