Results 131 to 140 of about 9,952 (165)

Instability of the Trypanosoma brucei rhodesiense metacyclic variable antigen repertoire

Nature, 1983
Trypanosoma brucei rhodesiense undergoes antigenic variation in its mammalian host by changing the glycoprotein composing its surface coat. Trypanosome clones which have the same repertoire of variable antigen types (VATs) are said to belong to the same serodeme. Tsetse flies infected with a particular serodeme extrude infective metacyclic trypanosomes
J D, Barry, J S, Crowe, K, Vickerman
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Trypanosoma rhodesiense and T. brucei: Absence of antibodies in chicken embryos

Experimental Parasitology, 1969
Abstract With the need to produce trypanosomes of constant antigenic type in mind, the antibody response of chicken embryos infected with Trypanosoma rhodesiense and T. brucei was examined. Embryos were infected at different ages (7–14 days of embryonic life) and sera were collected up to and after hatching. The postinoculation maintenance period
E, Goedbloed, B A, Southgate
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Experimental Chronic Trypanosoma brucei rhodesiense Infection in Microtus montanus

The American Journal of Tropical Medicine and Hygiene, 1983
Adult Microtus montanus were inoculated with a recently isolated strain of Trypanosoma brucei rhodesiense of human origin. The animals developed subacute to chronic infection and low-grade parasitemia. Histopathological examination of the heart revealed a severe pancarditis resulting in pronounced weight loss, and survival times of 5-8 weeks ...
J M, Bafort, H, Schmidt
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Activity of Bisphosphonates againstTrypanosoma bruceirhodesiense

Journal of Medicinal Chemistry, 2002
We report the results of a comparative molecular field analysis (CoMFA) investigation of the growth inhibition of the bloodstream form of Trypanosoma brucei rhodesiense trypomastigotes by bisphosphonates. A quantitative three-dimensional structure-activity relationship CoMFA model for a set of 26 bisphosphonates having a range of activity spanning ...
Michael B, Martin, John M, Sanders, Howard, Kendrick, Kate, de Luca-Fradley, Jared C, Lewis, Joshua S, Grimley, Erin M, Van Brussel, Jeffrey R, Olsen, Gary A, Meints, Agnieszka, Burzynska, Pawel, Kafarski, Simon L, Croft, Eric, Oldfield   +12 more
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Anaemia in human African trypanosomiasis caused by Trypanosoma brucei rhodesiense.

East African medical journal, 2004
To find out if indeed anaemia is a major sign in human trypanosomiasis caused by Trypanosoma brucei rhodensiense.A one year cross-sectional study of all admitted and surveyed Trypanosoma brucei rhodensiense infected patients (June 2001-June 2002)Nkhotakota District Hospital-Central Region of Malawi.After survey and investigations, 28 patients (16 males
Chisi, JE, Misiri, H, Zverev, Y, Nkhoma, A, Sternberg, JM   +4 more
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Nonvariant Antigens Limited to Bloodstream Forms of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense¹

The Journal of Protozoology, 1984
ABSTRACT. The presence of nonvariant antigens (NVAs) limited to bloodstream forms of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense was demonstrated for the first time by immunodiffusion and Immunoelectrophoresis. Noncloned and cloned populations were employed in preparation of polyclonal antisera in rabbits and of antigens to be used in
DAVID A. BEAT, HAROLD A. STANLEY, LESZEK CHOROMAŃSKL, A. BRUCE MacDONALD, B. M. HONIGBERG   +4 more
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Nonvariant antigens limited to bloodstream forms of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense.

The Journal of protozoology, 1985
The presence of nonvariant antigens (NVAs) limited to bloodstream forms of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense was demonstrated for the first time by immunodiffusion and immunoelectrophoresis. Noncloned and cloned populations were employed in preparation of polyclonal antisera in rabbits and of antigens to be used in the ...
D A, Beat, H A, Stanley, L, Choromański, A B, MacDonald, B M, Honigberg   +4 more
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A multiplex PCR that discriminates between Trypanosoma brucei brucei and zoonotic T. b. rhodesiense

Experimental Parasitology, 2008
Two subspecies of Trypanosoma brucei s.l. co-exist within the animal populations of Eastern Africa; T. b. brucei a parasite which only infects livestock and wildlife and T. b. rhodesiense a zoonotic parasite which infects domestic livestock, wildlife, and which in humans, results in the disease known as Human African Trypanosomiasis (HAT) or sleeping ...
Kim, Picozzi, Mark, Carrington, Susan C, Welburn   +2 more
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Filaments of "Trypanosoma brucei" : some notes on differences in origin and structure in two strains of "Trypanosoma (Trypanozoon) brucei rhodesiense"

Acta tropica, 1976
Filaments attached to trypanosomes of two strains of T. (T.) brucei were studied by electron microscopy and two distinct types identified: short-thick and long-thin. The former are associated with stumpy trypanosomes and are secretions, via the flagellar pocket, which originate in the area of the Golgi complex, during the infection of the host.
D S, Ellis, W E, Ormerod, W H, Lumsden
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The blood incubation infectivity test as a means of distinguishing between Trypanosoma brucei brucei and T. brucei rhodesiense

International Journal for Parasitology, 1973
Abstract Targett G. A. T. and Wilson V. C. L. C. 1973. The blood incubation infectivity test as a means of distinguishing between Trypanosoma brucei brucei and T. brucei rhodesiense. International Journal for Parasitology , 3: 5–11. A simple test for distinguishing between the morphologically identical subspecies Trypanosoma brucei ...
G A, Targett, V C, Wilson
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