Results 111 to 120 of about 59,489 (194)

GSK-3 kinase a putative therapeutic target in trypanosomatid parasites

Brazilian Journal of Infectious Diseases
Trypanosomatids are an important group of parasites that predominate in tropical and subtropical areas of the planet, which cause diseases that are classified as forgotten and neglected by the world health organization.
Alfredo Prado Diaz, Cristian Alejandro Meneses Canal, Alvaro José Valdés, Jaider Elian Giraldo Delgado, RE Varela-M   +4 more
doaj   +1 more source

The Alkaloid-Enriched Fraction of Pachysandra terminalis (Buxaceae) Shows Prominent Activity against Trypanosoma brucei rhodesiense. [PDF]

Molecules, 2021
Flittner D, Kaiser M, Mäser P, Lopes NP, Schmidt TJ.   +4 more
europepmc   +1 more source

A molecular mechanism for eflornithine resistance in African trypanosomes [PDF]

, 2010
Human African trypanosomiasis, endemic to sub-Saharan Africa, is invariably fatal if untreated. Its causative agent is the protozoan parasite Trypanosoma brucei.
Creek, Darren, Burchmore, Richard J S, Vincent, Isabel M, Watson, David G, Barrett, Michael P, Kamleh, Mohammed A, Woods, Debra J, Wong, Pui Ee   +7 more
core  

Physiological and proteomic profiles of Trypanosoma brucei rhodesiense parasite isolated from suramin responsive and non-responsive HAT patients in Busoga, Uganda. [PDF]

Int J Parasitol Drugs Drug Resist, 2021
Mutuku CN, Bateta R, Rono MK, Njunge JM, Awuoche EO, Ndung'u K, Mang'era CM, Akoth MO, Adung'a VO, Ondigo BN, Mireji PO.   +10 more
europepmc   +1 more source

Trypanosoma brucei rhodesiense [PDF]

, 2020
openaire   +1 more source

The use of Multiple Displacement Amplification to increase the detection and genotyping of Trypanosoma samples immobilised on FTA filters. [PDF]

, 2007
Whole genome amplification methods are a recently developed tool for amplifying DNA from limited template. We report its application in trypanosome infections, characterized by low parasitemias.
Sweeney, L., Turner, C.M.R., Morrison, L.J., Likeufack, A.C.L., Truc, P., Tait, A., McCormack, G., MacLeod, A.   +7 more
core  

Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model. [PDF]

PLoS One, 2020
Ndung'u K, Murilla GA, Thuita JK, Ngae GN, Auma JE, Gitonga PK, Thungu DK, Kurgat RK, Chemuliti JK, Mdachi RE.   +9 more
europepmc   +1 more source

Drug Synergism: Studies of Combination of RK-52 and Curcumin against Rhodesain of Trypanosoma brucei rhodesiense. [PDF]

ACS Med Chem Lett, 2020
Ettari R, Previti S, Di Chio C, Maiorana S, Allegra A, Schirmeister T, Zappalà M.   +6 more
europepmc   +1 more source

Roles of cytokines in modulating Trypanosoma brucei rhodesiense infection outcomes in vervet monkeys. [PDF]

Front Parasitol
Jebet C, Thuita JK, Masiga D, Orindi BO, Oidho J, Field MC, Matovu E, Adung'a VO.   +7 more
europepmc   +1 more source

Synthesis and Combination Studies of Novel Dipeptide Nitriles with Curcumin for a Potent Synergistic Action Against Rhodesain, Cysteine Protease of <i>Trypanosoma brucei rhodesiense</i>. [PDF]

Pharmaceuticals (Basel)
Di Chio C, Starvaggi J, Previti S, De Luca F, Natale B, Cosconati S, Schirmeister T, Zappalà M, Ettari R.   +8 more
europepmc   +1 more source