Results 101 to 110 of about 59,489 (194)

Antigenic variation in Trypanosoma brucei: joining the DOTs [PDF]

, 2008
African trypanosomes, such as <i>Trypanosoma brucei</i>, are protistan parasites that cause sleeping sickness. Though first described more than a century ago, trypanosomes remain a blight on the health of the human population and on the ...
Swiderski, Michal R., J David Barry, McCulloch, Richard, Michal R Swiderski, Chris Stockdale, McCulloch Richard, Barry, J. David, Stockdale Chris, Barry J. David, Stockdale, Chris, Richard McCulloch, Swiderski Michal R   +11 more
core   +1 more source

Drug Combination Studies of the Dipeptide Nitrile CD24 with Curcumin: A New Strategy to Synergistically Inhibit Rhodesain of Trypanosoma brucei rhodesiense. [PDF]

Int J Mol Sci, 2022
Di Chio C, Previti S, De Luca F, Bogacz M, Zimmer C, Wagner A, Schirmeister T, Zappalà M, Ettari R.   +8 more
europepmc   +1 more source

Mouse experiments demonstrate differential pathogenicity and virulence of Trypanosoma brucei rhodesiense strains. [PDF]

Exp Parasitol, 2021
Kipkorir LW, John TK, Owino OB, John O, Robert S, Daniel M, Owino AV.   +6 more
europepmc   +1 more source

Plasma Neuron-Specific Enolase is not a reliable biomarker for staging Trypanosoma brucei rhodesiense sleeping sickness patients. [PDF]

BMC Res Notes, 2022
Kato CD, Twesigye D, Alibu VP, Nanteza A, Nsubuga J, Mugasa CM, Matovu E.   +6 more
europepmc   +1 more source

Coenzyme Q₁₀ prevented Trypanosoma brucei rhodesiense-mediated breach of the blood brain barrier, inflammation and organ damage in late stage of Human African Trypanosomiasis. [PDF]

J Parasit Dis, 2023
Kitwan L, Makobe C, Mdachi R, Maranga DN, Isaac AO, Nyariki JN.   +5 more
europepmc   +1 more source

Plasma cytokines quantification among <i>Trypanosoma brucei rhodesiense</i> sleeping sickness cases and controls in Rumphi, Malawi. [PDF]

Malawi Med J, 2021
Kamoto K, Chiwaya A, Nambala P, Chammudzi P, Senga E, Chisi J, Matovu E, Musaya J.   +7 more
europepmc   +1 more source

Salvia officinalis L.: Antitrypanosomal Activity and Active Constituents against Trypanosoma brucei rhodesiense. [PDF]

Molecules, 2021
Llurba Montesino N, Kaiser M, Mäser P, Schmidt TJ.   +3 more
europepmc   +1 more source

Molecular docking to homology models of human and Trypanosoma brucei ERK8 that identified ortholog-specific inhibitors.

PLoS Neglected Tropical Diseases
Human African Trypanosomiasis (HAT), also known as sleeping sickness, is a lethal disease caused by two vector-borne parasites: Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense. The limited number of antitrypanosomal therapies for treating
Matthew Merski, Zachary B Mackey
doaj   +1 more source

Role of the inhibitor of serine peptidase 2 (ISP2) of Trypanosoma brucei rhodesiense in parasite virulence and modulation of the inflammatory responses of the host. [PDF]

PLoS Negl Trop Dis, 2021
Levy DJ, Goundry A, Laires RSS, Costa TFR, Novo CM, Grab DJ, Mottram JC, Lima APCA.   +7 more
europepmc   +1 more source

The pathogenicity of blood stream and central nervous system forms of <i>Trypanosoma brucei rhodesiense</i> trypanosomes in laboratory mice: a comparative study. [PDF]

F1000Res, 2022
Ndungu K, Thuita J, Murilla G, Kagira J, Auma J, Mireji P, Ngae G, Okumu P, Gitonga P, Guya S, Mdachi R.   +10 more
europepmc   +1 more source