Results 91 to 100 of about 14,283 (207)
Chemistry &Biodiversity, Volume 22, Issue 6, June 2025.Workflow of current study. ABSTRACT Malaria remains a significant public health challenge in Niger, accounting for 5.6% of global malaria‐related deaths. Local medicinal plants are frequently used as traditional treatments for malaria, although their efficacy and safety are often insufficiently investigated.
Souleymane Magagi Damé +4 more
wiley +1 more source
Biology of the Cell, Volume 117, Issue 6, June 2025.Protrusion‐derived extracellular vesicles (PD‐EVs) driving tumor progression and immune modulation. PD‐EVs arise from dynamic cellular extensions and serve as powerful communication tools. In cancer, they reshape the tumor microenvironment, promote angiogenesis and metastasis, and modulate immune responses, including T cell activation.
Mireia Gomez Duro +4 more
wiley +1 more source
Epidemiology of human African trypanosomiasis
Clinical Epidemiology, 2014 Jose R Franco,1 Pere P Simarro,1 Abdoulaye Diarra,2 Jean G Jannin1 1World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland; 2World Health Organization, Inter Country Support ...
Franco JR +3 more
doaj
Detection of group 1 Trypanosoma brucei gambiense by loop-mediated isothermal amplification [PDF]
, 2011 Trypanosoma brucei gambiense group 1 is the major causative agent of the Gambian human African trypanosomiasis (HAT). Accurate diagnosis of Gambian HAT is still challenged by lack of precise diagnostic methods, low and fluctuating parasitemia, and ...
Njiru, Z. K. +4 more
core +1 more source
Investigation of Novel Isatinylhydantoin Derivatives as Potential Anti‐Kinetoplastid Agents
ChemMedChem, Volume 20, Issue 1, January 2, 2025.A series of isatinylhydantoin derivatives were synthesized and investigated for antileishmanial and antitrypanosomal activities in vitro and in vivo. The derivative 5 was identified with higher leishmanicidal activity than the clinical drug amphotericin B while 4b was uncovered as in vitro trypanocidal hit against T. congolense parasite.
Keamogetswe Sechoaro +5 more
wiley +1 more source
A Clinical and Epidemiological Investigation of the First Reported Human Infection With the Zoonotic Parasite Trypanosoma evansi in Southeast Asia [PDF]
, 2016 Background. Trypanosoma is a genus of unicellular parasitic flagellate protozoa. Trypanosoma brucei species and Trypanosoma cruzi are the major agents of human trypanosomiasis; other Trypanosoma species can cause human disease, but are rare.
Baker, S +25 more
core +1 more source
The system of genetic exchange in Trypanosoma brucei and other trypanosomatids [PDF]
, 2007 In this chapter, we discuss our current understanding of the systems of genetic exchange in trypanosomatids and the im-pact the recent genome projects have had on this area of research.
MacLeod, A., Tait, A., Turner, C.M.R.
core
A co-evolutionary arms race: trypanosomes shaping the human genome, humans shaping the trypanosome genome [PDF]
, 2014 <i>Trypanosoma brucei</i> is the causative agent of African sleeping sickness in humans and one of several pathogens that cause the related veterinary disease Nagana.
Capewell, Paul +4 more
core +1 more source
Antiprotozoal Activity of Extracts of five Turkish Lamiaceae Species
Natural Product Communications, 2011 The in vitro antiprotozoal activities of crude methanolic extracts from the aerial parts of five Lamiaceae plants ( Salvia tomentosa, S. sclarea, S. dichroantha, Nepeta nuda subsp. nuda and Marrubium astracanicum subsp.
Hasan Kirmizibekmez +4 more
doaj +1 more source
Alkanediamide-Linked Bisbenzamidines Are Promising Antiparasitic Agents
Pharmaceuticals, 2016 A series of 15 alkanediamide-linked bisbenzamidines and related analogs was synthesized and tested in vitro against two Trypanosoma brucei (T.b.) subspecies: T.b. brucei and T.b.
Jean J. Vanden Eynde +7 more
doaj +1 more source