Results 61 to 70 of about 9,952 (165)
Quantitative Structure ‒ Antiprotozoal Activity Relationships of Sesquiterpene Lactones
Molecules, 2009 Prompted by results of our previous studies where we found high activity of some sesquiterpene lactones (STLs) against Trypanosoma brucei rhodesiense (which causes East African sleeping sickness), we have now conducted a structure-(in-vitro)-activity ...
Reto Brun +4 more
doaj +1 more source
New tsetse (Glossina fuscipes fuscipes) genomes generated from wild and laboratory‐reared specimens
Insect Science, Volume 32, Issue 5, Page 1588-1596, October 2025.Abstract Tsetse (Glossina spp.) are vectors of African trypanosomes that cause devastating human and animal African trypanosomiases. While much of the research to better understand tsetse genetics and physiology relies on colony‐reared flies, these flies may not represent the genetic diversity found in natural wild populations due to their long‐term ...
Daniel J. Bruzzese +5 more
wiley +1 more source
In Vitro Leishmanicidal Efficacy of Synthesized Arylidene Analogues of Glitazone
Drug Development Research, Volume 86, Issue 5, August 2025.ABSTRACT Diabetes is a fast‐growing health issue in low‐ and middle‐income countries, with ~80% of diabetics living in the tropics and sub‐tropics. It is a deadly condition claiming the lives of millions of individuals annually, with no therapeutic treatment available to date. The management of diabetes is thus limited to symptomatic relief by glycemic
Janine Aucamp +4 more
wiley +1 more source
Epidemiology of human African trypanosomiasis
Clinical Epidemiology, 2014 Jose R Franco,1 Pere P Simarro,1 Abdoulaye Diarra,2 Jean G Jannin1 1World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland; 2World Health Organization, Inter Country Support ...
Franco JR +3 more
doaj
Chemical Constituents From the Ethyl Acetate Extract of
Natural Product Communications, 2019 One new triterpenoid, 3β- O -(2-hydroxybenzoyl)-ursolic acid ( 1 ), and 11 known compounds, including 5 triterpenoids, 2 steroidal compounds, and 4 phenolic compounds were isolated from the ethyl acetate extract of the aerial parts of Salvia hydrangea ...
Majid B. Kahnamoei +5 more
doaj +1 more source
Estimating the burden of rhodesiense sleeping sickness during an outbreak in Serere, eastern Uganda
BMC Public Health, 2008 Background Zoonotic sleeping sickness, or HAT (Human African Trypanosomiasis), caused by infection with Trypanosoma brucei rhodesiense, is an under-reported and neglected tropical disease.
Coleman Paul G +4 more
doaj +1 more source
The Burden of Neglected Tropical Diseases in Rwanda: A Scoping Review
Health Science Reports, Volume 8, Issue 8, August 2025.ABSTRACT Background and Aims Rwanda is among the African countries affected by neglected tropical diseases (NTDs). This scoping review aims to synthesize available information to understand the prevalence, incidence, distribution, morbidity, mortality, and risk factors of NTDs in Rwanda.
Masceline Jenipher Mutsaka‐Makuvaza +9 more
wiley +1 more source
Chemistry &Biodiversity, Volume 22, Issue 6, June 2025.Workflow of current study. ABSTRACT Malaria remains a significant public health challenge in Niger, accounting for 5.6% of global malaria‐related deaths. Local medicinal plants are frequently used as traditional treatments for malaria, although their efficacy and safety are often insufficiently investigated.
Souleymane Magagi Damé +4 more
wiley +1 more source
Antiprotozoal Activity of Extracts of five Turkish Lamiaceae Species
Natural Product Communications, 2011 The in vitro antiprotozoal activities of crude methanolic extracts from the aerial parts of five Lamiaceae plants ( Salvia tomentosa, S. sclarea, S. dichroantha, Nepeta nuda subsp. nuda and Marrubium astracanicum subsp.
Hasan Kirmizibekmez +4 more
doaj +1 more source
A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense.
PLoS Neglected Tropical Diseases, 2016 Humans are protected against infection from most African trypanosomes by lipoprotein complexes present in serum that contain the trypanolytic pore-forming protein, Apolipoprotein L1 (APOL1).
Anneli Cooper +7 more
doaj +1 more source