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Expression of foreign proteins in Trypanosoma congolense
Molecular and Biochemical Parasitology, 1999An expression vector was constructed to express foreign genes in Trypanosoma congolense. The foreign gene and a neomycin phosphotransferase (NPT) gene are flanked by glutamate and alanine rich protein (GARP) gene processing signals and their expression is driven by a ribosomal RNA gene promoter.
N, Downey, J E, Donelson
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Sequential infection of tsetse flies with Trypanosoma congolense and Trypanosoma brucei
Acta Tropica, 1992The question whether tsetse flies can be experimentally infected with more than one trypanosome species or strain by sequential feeding was investigated using DNA probe technology to identify directly the small numbers of trypanosomes in the fly gut. Bloodstream form trypanosomes of Trypanosoma congolense or T. brucei ssp.
W, Gibson, V, Ferris
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Congenital transmission of Trypanosoma congolense in mice
Journal of Comparative Pathology, 1983Pregnant mice were infected with a strain of T. congolense which produces a chronic infection, to determine if congenital infection can occur. Some of the mice were killed before delivery and tissues of foetuses injected into clean male mice. Other mothers were allowed to deliver and the tissues of some of the 1-day-old young inoculated into male mice ...
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Mitogenicity of autolysates ofTrypanosoma congolense
Experientia, 1978Autolysates of Trypanosoma congolense, in subcytotoxic amounts, were found to be highly mitogenic in vitro for the spleen cells of normal mice. Significant amounts of [3H]-thymidine were also incorporated by the responding spleen cells of nu/nu (athymic) mice. In contrast, the spleen cells of cyclophosphamide-treated mice were unresponsive.
R K, Assoku, I R, Tizard
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Genetic resistance to Trypanosoma congolense infections in mice
Infection and Immunity, 1980The mechanisms of genetic resistance or "trypanotolerance" to infection with Trypanosoma congolense were investigated in two strains of mice. One strain C57BL, is outstandingly resistant to most stabilates of T. congolense and can survive for over 80 days, whereas CFLP, in common with most other strains, generally succumbs in less than 20 days ...
D D, Whitelaw +4 more
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Trypanosoma congolense: Infectivity for white mice
Experimental Parasitology, 1968Abstract White mice of Swiss strain are susceptible to Trypanosoma congolense. Intact, splenectomized, irradiated, or irradiated and splenectomized mice showed no variation in susceptibility to infection. The incubation period varied from 4 to 19 days.
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Trypanosoma congolense: Thrombocyte survival in infected steers
Experimental Parasitology, 1982Abstract Charolais steers infected with Trypanosoma congolense developed a thrombocytopenia that was first demonstrated shortly before the onset of parasitemia. The thrombocyte count progressively decreased from a level of 6 × 105/mm3 on the 3rd day postinfection to l × 105/mm3, its most depressed level, on the 11th day postinfection. The mean of the
J M, Preston, R M, Kovatch, B T, Wellde
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Types ofTrypanosoma Congolense
Annals of Tropical Medicine & Parasitology, 1960(1960). Types of Trypanosoma Congolense. Annals of Tropical Medicine & Parasitology: Vol. 54, No. 4, pp. 428-438.
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The susceptibility of strains of mice to infection with Trypanosoma congolense
Research in Veterinary Science, 1978The survival times of a number of strains of mice after infection with a stabilate of Trypanosoma brucei or of T congolense were examined. The mean survival times of all the strains when infected with T brucei TREU 667 ranged from 27 to 63 days. Greater disparity was observed after infection with T congolense GVR1 where the mean survival time ranged ...
F W, Jennings +3 more
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