Results 1 to 10 of about 77,950 (200)
Trypanosoma cruzi: circulating antigens [PDF]
Memorias do Instituto Oswaldo Cruz, 1981 Circulating antigens were detected in sera of mice experimentally infected with a high close of Trypanosoma cruzi by reaction with sera from chronically infected mice.
V. Bongertz +2 more
doaj +4 more sources
Glycosomal Phosphoenolpyruvate Carboxykinase CRISPR/Cas9-Deletion and Its Role in Trypanosoma cruzi Metacyclogenesis and Infectivity in Mammalian Host. [PDF]
FASEB JEffects of PEPCK deficiency in Trypanosoma cruzi bioenergetics and life stages. ABSTRACT Trypanosoma cruzi, the causative agent of Chagas disease, possesses glycosomes—unique organelles that house key metabolic enzymes, several of which are promising therapeutic targets.
Vieira CSD +8 more
europepmc +2 more sources
High Trypanosoma spp. diversity is maintained by bats and triatomines in Espírito Santo state, Brazil. [PDF]
PLoS ONE, 2017 The aim of this study was to reevaluate the ecology of an area in the Atlantic Forest, southeast Brazil, where Chagas disease (CD) has been found to occur.
Maria Augusta Dario +10 more
doaj +11 more sources
Amides from Porcelia ponderosa Roots Display Efficacy In Vitro Against Intracellular Amastigotes of Trypanosoma cruzi. [PDF]
Chem BiodiversAmides from Porcelia ponderosa display potent activity against amastigotes from Trypanosoma cruzi. ABSTRACT In the present work, the MeOH extract from roots of Porcelia ponderosa R.E. Fries (Annonaceae) was subjected to several chromatographic techniques to afford three chemically related amides: N‐trans‐p‐coumaroyltyramine (1), N‐trans ...
Dos Santos CHT +6 more
europepmc +2 more sources
How to improve the early diagnosis of Trypanosoma cruzi infection: Relationship between validated conventional diagnosis and quantitative DNA amplification in congenitally infected children [PDF]
, 2013 BACKGROUND: According to the Chagas congenital transmission guides, the diagnosis of infants, born to Trypanosoma cruzi infected mothers, relies on the detection of parasites by INP micromethod, and/or the persistence of T. cruzi specific antibody titers
Bua, Jacqueline Elena +7 more
core +26 more sources
Trends in Parasitology, 2020 Trypanosoma cruzi is the etiological agent of American trypanosomiasis, or Chagas disease, and is transmitted mainly by blood-sucking reduviid insects in endemic countries. Metacyclic trypomastigotes released in the feces during the insect blood meal enter a mammalian host through skin wounds or mucosal membranes and invade sur- rounding cells.
Moretti, Nilmar Silvio UNIFESP +2 more
openaire +4 more sources
Broadening the spectrum of ivermectin: Its effect on Trypanosoma cruzi and related trypanosomatids
Frontiers in Cellular and Infection Microbiology, 2022 Chagas disease is an endemic American parasitosis, caused by Trypanosoma cruzi. The current therapies, benznidazole (BZN) and nifurtimox (NFX), show limited efficacy and multiple side effects. Thus, there is a need to develop new trypanocidal strategies.
Laura Fraccaroli +6 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 T. cruzi, the causal agent of Chagas disease, is a parasite able to infect different types of host cells and to persist chronically in the tissues of human and animal hosts.
Cynthia Vanesa Rivero +13 more
doaj +1 more source
Current Research in Microbial Sciences, 2022 Trypanosoma cruzi, the etiologic agent of Chagas disease (CD) presents a wide genetic and phenotypic diversity that is classified into seven lineages or discrete typing units (DTU: TcI to TcVI and Tcbat).
Santiago José Martinez +5 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 Chagas disease, caused by the parasite Trypanosoma cruzi, is an infectious illness endemic to Latin America and still lacks an effective treatment for the chronic stage.
María Cristina Vanrell +8 more
doaj +1 more source