High Trypanosoma spp. diversity is maintained by bats and triatomines in Espírito Santo state, Brazil. [PDF]
PLoS ONE, 2017 The aim of this study was to reevaluate the ecology of an area in the Atlantic Forest, southeast Brazil, where Chagas disease (CD) has been found to occur.
Maria Augusta Dario +10 more
doaj +10 more sources
High prevalence of Trypanosoma cruzi infection in shelter dogs from southern Louisiana, USA
Parasites & Vectors, 2019 Background Chagas disease is a zoonotic disease caused by the protozoan parasite Trypanosoma cruzi. The role of dogs as sentinels has been proposed in multiple regions, as they are a domestic reservoir for T. cruzi.
Ardem Elmayan +7 more
doaj +2 more sources
Trypanosoma cruzi: circulating antigens [PDF]
Memorias do Instituto Oswaldo Cruz, 1981 Circulating antigens were detected in sera of mice experimentally infected with a high close of Trypanosoma cruzi by reaction with sera from chronically infected mice.
V. Bongertz +2 more
doaj +5 more sources
Host-parasite interaction: changes in human placental gene expression induced by Trypanosoma cruzi
Parasites & Vectors, 2018 Background Chagas disease is caused by Trypanosoma cruzi, a parasite endemic to Latin America. Most infections occur in children by vector or congenital transmission.
Christian Castillo +6 more
doaj +2 more sources
Quantification of Trypanosoma cruzi in Tissue and Trypanosoma cruzi Killing Assay. [PDF]
BIO-PROTOCOL, 2017 Infection with Trypanosoma cruzi causes Chagas disease. The methods provided here allow for the quantification of T. cruzi in the liver, heart, and blood of intraperitoneally-infected mice and analysis of the killing activity of the cells infected with T.
H. Kayama, S. Kitada, K. Takeda
semanticscholar +4 more sources
Parasites & Vectors, 2017 Background The DNA barcoding system using the cytochrome c oxidase subunit 1 mitochondrial gene (cox1 or COI) is highly efficient for discriminating vertebrate and invertebrate species.
Marina Silva Rodrigues +2 more
doaj +2 more sources
Molecular diagnosis of Trypanosoma cruzi.
Acta Tropica, 2018 Chagas disease, caused by the kinetoplastid protozoan Trypanosoma cruzi, affects millions of people, most of them neglected populations. The different phases of the disease, the transmission mode and the high genetic variability of the parasite determine that molecular detection methods display different degree of success.
A. Schijman
semanticscholar +5 more sources
Benznidazole biotransformation and multiple targets in Trypanosoma cruzi revealed by metabolomics [PDF]
, 2014 <b>Background</b><p></p> The first line treatment for Chagas disease, a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi, involves administration of benznidazole (Bzn). Bzn is a 2-nitroimidazole pro-
A Kamleh +73 more
core +48 more sources
Exploring Trypanosoma cruzi transmission dynamics in an acute Chagas disease outbreak using next-generation sequencing [PDF]
Parasites & VectorsBackground Chagas disease (CD), caused by Trypanosoma cruzi, poses a major global public health challenge. Although vector-borne transmission is the primary mode of infection, oral transmission is increasingly concerning. Methods This study utilized long-
Lissa Cruz-Saavedra +15 more
doaj +2 more sources
Broadening the spectrum of ivermectin: Its effect on Trypanosoma cruzi and related trypanosomatids
Frontiers in Cellular and Infection Microbiology, 2022 Chagas disease is an endemic American parasitosis, caused by Trypanosoma cruzi. The current therapies, benznidazole (BZN) and nifurtimox (NFX), show limited efficacy and multiple side effects. Thus, there is a need to develop new trypanocidal strategies.
Laura Fraccaroli +6 more
doaj +1 more source