High Trypanosoma spp. diversity is maintained by bats and triatomines in Espírito Santo state, Brazil. [PDF]
PLoS ONE, 2017 The aim of this study was to reevaluate the ecology of an area in the Atlantic Forest, southeast Brazil, where Chagas disease (CD) has been found to occur.
Maria Augusta Dario +10 more
doaj +17 more sources
Detection of Trypanosoma cruzi in a Reactive Blood Bank Sample in Sonora, Mexico [PDF]
Tropical Medicine and Infectious DiseaseChagas disease is a neglected disease caused by the parasite Trypanosoma cruzi, a public health problem in both endemic and non-endemic countries. In Mexico, the southern region is considered endemic, and cases are frequently reported; however, in the ...
Idalia Paredes-Sotelo +8 more
doaj +2 more sources
Trypanosoma cruzi: circulating antigens [PDF]
Memorias do Instituto Oswaldo Cruz, 1981 Circulating antigens were detected in sera of mice experimentally infected with a high close of Trypanosoma cruzi by reaction with sera from chronically infected mice.
V. Bongertz +2 more
doaj +5 more sources
High prevalence of Trypanosoma cruzi infection in shelter dogs from southern Louisiana, USA
Parasites & Vectors, 2019 Background Chagas disease is a zoonotic disease caused by the protozoan parasite Trypanosoma cruzi. The role of dogs as sentinels has been proposed in multiple regions, as they are a domestic reservoir for T. cruzi.
Ardem Elmayan +7 more
doaj +2 more sources
Host-parasite interaction: changes in human placental gene expression induced by Trypanosoma cruzi
Parasites & Vectors, 2018 Background Chagas disease is caused by Trypanosoma cruzi, a parasite endemic to Latin America. Most infections occur in children by vector or congenital transmission.
Christian Castillo +6 more
doaj +2 more sources
Parasites & Vectors, 2017 Background The DNA barcoding system using the cytochrome c oxidase subunit 1 mitochondrial gene (cox1 or COI) is highly efficient for discriminating vertebrate and invertebrate species.
Marina Silva Rodrigues +2 more
doaj +2 more sources
Molecular diagnosis of Trypanosoma cruzi.
Acta Tropica, 2018 Chagas disease, caused by the kinetoplastid protozoan Trypanosoma cruzi, affects millions of people, most of them neglected populations. The different phases of the disease, the transmission mode and the high genetic variability of the parasite determine that molecular detection methods display different degree of success.
A. Schijman
semanticscholar +5 more sources
Trypanosoma cruzi IIc: phylogenetic and phylogeographic insights from sequence and microsatellite analysis and potential impact on emergent Chagas disease. [PDF]
, 2009 Trypanosoma cruzi, the etiological agent of Chagas disease, is highly genetically diverse. Numerous lines of evidence point to the existence of six stable genetic lineages or DTUs: TcI, TcIIa, TcIIb, TcIIc, TcIId, and TcIIe.
Acosta, Nidia +9 more
core +35 more sources
Broadening the spectrum of ivermectin: Its effect on Trypanosoma cruzi and related trypanosomatids
Frontiers in Cellular and Infection Microbiology, 2022 Chagas disease is an endemic American parasitosis, caused by Trypanosoma cruzi. The current therapies, benznidazole (BZN) and nifurtimox (NFX), show limited efficacy and multiple side effects. Thus, there is a need to develop new trypanocidal strategies.
Laura Fraccaroli +6 more
doaj +1 more source
Trypanosoma cruzi genetic diversity: impact on transmission cycles and Chagas disease
Memórias do Instituto Oswaldo Cruz, 2022 Trypanosoma cruzi, the agent of Chagas disease (ChD), exhibits remarkable biological and genetic diversity, along with eco-epidemiological complexity. In order to facilitate communication among researchers aiming at the characterisation of biological and
B. Zingales, D. Bartholomeu
semanticscholar +1 more source