Results 11 to 20 of about 144,739 (262)

High Trypanosoma spp. diversity is maintained by bats and triatomines in Espírito Santo state, Brazil. [PDF]

PLoS ONE, 2017
The aim of this study was to reevaluate the ecology of an area in the Atlantic Forest, southeast Brazil, where Chagas disease (CD) has been found to occur.
Maria Augusta Dario, Cristiane Varella Lisboa, Luciana M Costa, Ricardo Moratelli, Monique Pereira Nascimento, Leonora Pires Costa, Yuri Luiz Reis Leite, Martin S Llewellyn, Samanta Cristina das Chagas Xavier, André Luiz Rodrigues Roque, Ana Maria Jansen   +10 more
doaj   +17 more sources

How to improve the early diagnosis of Trypanosoma cruzi infection: Relationship between validated conventional diagnosis and quantitative DNA amplification in congenitally infected children [PDF]

, 2013
BACKGROUND: According to the Chagas congenital transmission guides, the diagnosis of infants, born to Trypanosoma cruzi infected mothers, relies on the detection of parasites by INP micromethod, and/or the persistence of T. cruzi specific antibody titers
Bua, Jacqueline Elena, Cardoni, Rita Liliana, de Rissio, Ana María, Perrone, Alina Elizabeth, Ruiz, Andrés Mariano, Scollo, Karenina, Velázquez, Elsa Beatriz, Volta, Bibiana Julieta   +7 more
core   +34 more sources

Trypanosoma cruzi P21 Is a Pleiotropic Protein That Is Involved in Parasite Host Cell Invasion and Intracellular Parasitism. [PDF]

Microbiologyopen
This study reveals the pleiotropic role of Trypanosoma cruzi P21 protein in the low‐virulence G strain. P21 knockout significantly impairs parasite invasion, intracellular multiplication, and egress in vitro. In vivo, P21 deficiency leads to reduced cardiac tissue parasitism, suggesting its role in establishing and maintaining silent infections.
Uombe NPI, Velikkakam T, Silveira ACA, Rodrigues CC, Borges BC, Teixeira TL, Pereira CL, Servato JPS, Melo NS, Mortara RA, Silveira JFD, Silva CVD.   +11 more
europepmc   +2 more sources

Variation in surface protein expression leads to heterogeneous Trypanosoma cruzi populations during host cell infection. [PDF]

Nat Commun
Cruz-Saavedra L, Loock M, Antunes LB, Cestari I.   +3 more
europepmc   +3 more sources

Alpha-Tubulin Acetylation in Trypanosoma cruzi: A Dynamic Instability of Microtubules Is Required for Replication and Cell Cycle Progression

Frontiers in Cellular and Infection Microbiology, 2021
Trypanosomatids have a cytoskeleton arrangement that is simpler than what is found in most eukaryotic cells. However, it is precisely organized and constituted by stable microtubules.
Victoria Lucia Alonso, Victoria Lucia Alonso, Mara Emilia Carloni, Camila Silva Gonçalves, Camila Silva Gonçalves, Gonzalo Martinez Peralta, Gonzalo Martinez Peralta, Maria Eugenia Chesta, Alejandro Pezza, Luis Emilio Tavernelli, Maria Cristina M. Motta, Maria Cristina M. Motta, Esteban Serra, Esteban Serra   +13 more
doaj   +1 more source

Effects of TcFLA-1BP and TcGP72 Deletion on the Infectivity and Survival of Trypanosoma cruzi in Cell Cultures. [PDF]

Cell Biol Int
ABSTRACT Chagas disease, caused by the protozoan Trypanosoma cruzi, is a neglected tropical disease with limited treatment options and no available vaccine. Understanding the role of proteins in the parasite's biological cycle is critical for advancing vaccine development and optimizing therapies.
Souza-Melo N, de Souza GH, de Souza W.
europepmc   +2 more sources

Endocytic Rabs Are Recruited to the Trypanosoma cruzi Parasitophorous Vacuole and Contribute to the Process of Infection in Non-professional Phagocytic Cells

Frontiers in Cellular and Infection Microbiology, 2020
Trypanosoma cruzi is the parasite causative of Chagas disease, a highly disseminated illness endemic in Latin-American countries. T. cruzi has a complex life cycle that involves mammalian hosts and insect vectors both of which exhibits different ...
Betiana Nebaí Salassa, Betiana Nebaí Salassa, Juan Agustín Cueto, Juan Agustín Cueto, Julián Gambarte Tudela, Patricia Silvia Romano, Patricia Silvia Romano   +6 more
doaj   +1 more source

Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease

bioRxiv, 2020
The protozoan Trypanosoma cruzi almost invariably establishes life-long infections in humans and other mammals, despite the development of potent host immune responses that constrain parasite numbers. The consistent, decades-long persistence of T.
Wei Wang, D. Peng, R. Baptista, Yiran Li, J. Kissinger, R. Tarleton   +5 more
semanticscholar   +1 more source

Acute Phase Proteins in Dogs with Natural Infection by Trypanosoma cruzi

Tropical Medicine and Infectious Disease, 2023
Acute phase proteins have been used as tools for the diagnosis, monitoring, and prognosis of several diseases in domestic animals. However, the dynamics of these proteins in infection by Trypanosoma cruzi, the causative agent of Chagas disease in dogs ...
Pilar Rivadeneira-Barreiro, Roberto Montes-de-Oca-Jiménez, Pablo Zambrano-Rodríguez, Juan Carlos Vázquez-Chagoyán, Adriana del Carmen Gutiérrez-Castillo, Luis Pardo-Marin, Lorena Franco-Martínez, José Joaquín Cerón, Silvia Martínez-Subiela   +8 more
doaj   +1 more source

Landmarks of the Knowledge and Trypanosoma cruzi Biology in the Wild Environment

Frontiers in Cellular and Infection Microbiology, 2020
Trypanosomatids are ancient parasitic eukaryotes that still maintain prokaryotic characteristics. Trypanosoma cruzi, a primarily wild mammal parasite, infected humans already long before European colonization of the Americas. T.
A. Jansen, S. Xavier, A. L. R. Roque
semanticscholar   +1 more source