Results 11 to 20 of about 143,738 (310)

A Review on the Immunological Response against Trypanosoma cruzi

Pathogens, 2023
Chagas disease is a chronic systemic infection transmitted by Trypanosoma cruzi. Its life cycle consists of different stages in vector insects and host mammals. Trypanosoma cruzi strains cause different clinical manifestations of Chagas disease alongside
G. Macaluso, Francesca Grippi, S. Di Bella, V. Blanda, Francesca Gucciardi, A. Torina, A. Guercio, V. Cannella   +7 more
semanticscholar   +1 more source

Repurposing Carvedilol as a Novel Inhibitor of the Trypanosoma cruzi Autophagy Flux That Affects Parasite Replication and Survival

Frontiers in Cellular and Infection Microbiology, 2021
T. cruzi, the causal agent of Chagas disease, is a parasite able to infect different types of host cells and to persist chronically in the tissues of human and animal hosts.
Cynthia Vanesa Rivero, Cynthia Vanesa Rivero, Santiago José Martínez, Santiago José Martínez, Paul Novick, Juan Agustín Cueto, Betiana Nebaí Salassa, María Cristina Vanrell, Xiaomo Li, Carlos Alberto Labriola, Luis Mariano Polo, David M. Engman, Joachim Clos, Patricia Silvia Romano   +13 more
doaj   +1 more source

Trypanosoma cruzi genetic diversity: impact on transmission cycles and Chagas disease

Memórias do Instituto Oswaldo Cruz, 2022
Trypanosoma cruzi, the agent of Chagas disease (ChD), exhibits remarkable biological and genetic diversity, along with eco-epidemiological complexity. In order to facilitate communication among researchers aiming at the characterisation of biological and
B. Zingales, D. Bartholomeu
semanticscholar   +1 more source

Review on Experimental Treatment Strategies Against Trypanosoma cruzi

Journal of Experimental Pharmacology, 2021
Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma cruzi. Currently, only nitroheterocyclic nifurtimox (NFX) and benznidazole (BNZ) are available for the treatment of Chagas disease, with limitations such as variable ...
A. L. Mazzeti, P. Capelari-Oliveira, M. T. Bahia, V. C. Mosqueira   +3 more
semanticscholar   +1 more source

Biological features of TcM: A new Trypanosoma cruzi isolate from Argentina classified into TcV lineage

Current Research in Microbial Sciences, 2022
Trypanosoma cruzi, the etiologic agent of Chagas disease (CD) presents a wide genetic and phenotypic diversity that is classified into seven lineages or discrete typing units (DTU: TcI to TcVI and Tcbat).
Santiago José Martinez, Gonzalo Nicolás Nardella, Matías Exequiel Rodríguez, Cynthia Vanesa Rivero, Fernán Agüero, Patricia Silvia Romano   +5 more
doaj   +1 more source

Induction of Autophagy by Ursolic Acid Promotes the Elimination of Trypanosoma cruzi Amastigotes From Macrophages and Cardiac Cells

Frontiers in Cellular and Infection Microbiology, 2022
Chagas disease, caused by the parasite Trypanosoma cruzi, is an infectious illness endemic to Latin America and still lacks an effective treatment for the chronic stage.
María Cristina Vanrell, María Cristina Vanrell, Santiago José Martinez, Lucila Ibel Muñoz, Betiana Nebaí Salassa, Betiana Nebaí Salassa, Julián Gambarte Tudela, Patricia Silvia Romano, Patricia Silvia Romano   +8 more
doaj   +1 more source

Alpha-Tubulin Acetylation in Trypanosoma cruzi: A Dynamic Instability of Microtubules Is Required for Replication and Cell Cycle Progression

Frontiers in Cellular and Infection Microbiology, 2021
Trypanosomatids have a cytoskeleton arrangement that is simpler than what is found in most eukaryotic cells. However, it is precisely organized and constituted by stable microtubules.
Victoria Lucia Alonso, Victoria Lucia Alonso, Mara Emilia Carloni, Camila Silva Gonçalves, Camila Silva Gonçalves, Gonzalo Martinez Peralta, Gonzalo Martinez Peralta, Maria Eugenia Chesta, Alejandro Pezza, Luis Emilio Tavernelli, Maria Cristina M. Motta, Maria Cristina M. Motta, Esteban Serra, Esteban Serra   +13 more
doaj   +1 more source

Characterization of Trypanosoma cruzi [PDF]

Memórias do Instituto Oswaldo Cruz, 1999
Departamento de Bioquimica e Imunologia, ICB-UFMG, 30270-010 Belo Horizonte, MG, Brasil *Laboratoriode Parasitologia Celular e Molecular, Centro de Pesquisas Rene Rachou-Fiocruz, Av. Augusto de Lima 1715,30190-002, Belo Horizonte, MG, BrasilKey words: Trypanosoma cruzi - genetic variation - populational ...
Silvane M. F. Murta, Silvane M. F. Murta, Alvaro J. Romanha   +2 more
openaire   +5 more sources

Trypanosoma cruzi

Biomédica: revista del Instituto Nacional de Salud, 2000
María Teresa Palá, Luis E. Gualdrón
doaj   +3 more sources

Endocytic Rabs Are Recruited to the Trypanosoma cruzi Parasitophorous Vacuole and Contribute to the Process of Infection in Non-professional Phagocytic Cells

Frontiers in Cellular and Infection Microbiology, 2020
Trypanosoma cruzi is the parasite causative of Chagas disease, a highly disseminated illness endemic in Latin-American countries. T. cruzi has a complex life cycle that involves mammalian hosts and insect vectors both of which exhibits different ...
Betiana Nebaí Salassa, Betiana Nebaí Salassa, Juan Agustín Cueto, Juan Agustín Cueto, Julián Gambarte Tudela, Patricia Silvia Romano, Patricia Silvia Romano   +6 more
doaj   +1 more source