Trypanosoma cruzi: circulating antigens [PDF]
Circulating antigens were detected in sera of mice experimentally infected with a high close of Trypanosoma cruzi by reaction with sera from chronically infected mice.
V. Bongertz+2 more
doaj +5 more sources
Quantification of Trypanosoma cruzi in Tissue and Trypanosoma cruzi Killing Assay [PDF]
Infection with Trypanosoma cruzi causes Chagas disease. The methods provided here allow for the quantification of T. cruzi in the liver, heart, and blood of intraperitoneally-infected mice and analysis of the killing activity of the cells infected with T.
Hisako Kayama+2 more
doaj +4 more sources
Characterization of Trypanosoma cruzi [PDF]
Departamento de Bioquimica e Imunologia, ICB-UFMG, 30270-010 Belo Horizonte, MG, Brasil *Laboratoriode Parasitologia Celular e Molecular, Centro de Pesquisas Rene Rachou-Fiocruz, Av. Augusto de Lima 1715,30190-002, Belo Horizonte, MG, BrasilKey words: Trypanosoma cruzi - genetic variation - populational ...
Silvane M. F. Murta+2 more
openaire +5 more sources
The N-myristoylome of Trypanosoma cruzi [PDF]
AbstractProtein N-myristoylation is catalysed by N-myristoyltransferase (NMT), an essential and druggable target in Trypanosoma cruzi, the causative agent of Chagas’ disease. Here we have employed whole cell labelling with azidomyristic acid and click chemistry to identify N-myristoylated proteins in different life cycle stages of the parasite.
Roberts, Adam J., Fairlamb, Alan
openaire +4 more sources
Different serological cross-reactivity of Trypanosoma rangeli forms in Trypanosoma cruzi-infected patients sera [PDF]
Background American Trypanosomiasis or Chagas disease is caused by Trypanosoma cruzi which currently infects approximately 16 million people in the Americas causing high morbidity and mortality.
de Moraes, Milene H.+7 more
core +3 more sources
Molecular epidemiology of domestic and sylvatic Trypanosoma cruzi infection in rural northwestern Argentina [PDF]
Genetic diversity of Trypanosoma cruzi populations and parasite transmission dynamics have been well documented throughout the Americas, but few studies have been conducted in the Gran Chaco ecoregion, one of the most highly endemic areas for Chagas ...
Cardinal, Marta Victoria+8 more
core +1 more source
Plasminogen interaction with Trypanosoma cruzi [PDF]
The ability of Trypanosoma cruzi to interact with plasminogen, the zimogenic form of the blood serin protease plasmin, was examined. Immunohistochemistry studies revealed that both forms, epimastigotes and metacyclic trypomastigotes, were able to fix plasminogen in a lysine dependant manner.
Laura Almeida+4 more
openaire +5 more sources
Molecular and antigenic characterization of Trypanosoma cruzi TolT proteins [PDF]
Background: TolT was originally described as a Trypanosoma cruzi molecule that accumulated on the trypomastigote flagellum bearing similarity to bacterial TolA colicins receptors.
Agüero, Fernan Gonzalo+13 more
core +1 more source
Phylogenetic analysis of Bolivian bat trypanosomes of the subgenus schizotrypanum based on cytochrome B sequence and minicircle analyses. [PDF]
The aim of this study was to establish the phylogenetic relationships of trypanosomes present in blood samples of Bolivian Carollia bats. Eighteen cloned stocks were isolated from 115 bats belonging to Carollia perspicillata (Phyllostomidae) from three ...
Lineth García+5 more
doaj +1 more source
The Ly49E receptor inhibits the immune control of acute Trypanosoma cruzi infection [PDF]
The protozoan parasite Trypanosoma cruzi circulates in the blood upon infection and invades various cells. Parasites intensively multiply during the acute phase of infection and persist lifelong at low levels in tissues and blood during the chronic phase.
Almeida+48 more
core +2 more sources