Results 21 to 30 of about 88,689 (264)
The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]
Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease.
Campetella, O.+4 more
core +2 more sources
Clathrin expression in Trypanosoma cruzi [PDF]
Clathrin-mediated vesicular trafficking, the mechanism by which proteins and lipids are transported between membrane-bound organelles, accounts for a large proportion of import from the plasma membrane (endocytosis) and transport from the trans-Golgi network towards the endosomal system.
Ligia Cristina Kalb+6 more
openaire +3 more sources
Protective immunity against Trypanosoma cruzi [PDF]
Upon infection, Trypanosoma cruzi triggers a strong immune response that has both protective and pathological consequences. In this work, several important questions regarding protective immunity are reviewed.
Basombrío, Miguel Ángel Manuel+2 more
core +1 more source
Profiling the Trypanosoma cruzi Phosphoproteome [PDF]
Protein phosphorylation is a reversible post-translational modification essential for the regulation of several signal transduction pathways and biological processes in the living cell. Therefore, the identification of protein phosphorylation sites is crucial to understand cell signaling control at the molecular level.
Marco Aurélio Krieger+8 more
openaire +5 more sources
INTRODUÇÃO: A transmissão transfusional da tripanossomíase americana tem-se reduzido no Brasil, com a progressiva ampliação do controle de qualidade do sangue.
Ana M. Bonametti+4 more
doaj +3 more sources
Trypanosoma Species in Small Nonflying Mammals in an Area With a Single Previous Chagas Disease Case
Trypanosomatids are hemoflagellate parasites that even though they have been increasingly studied, many aspects of their biology and taxonomy remain unknown. The aim of this study was to investigate the Trypanosoma sp.
Maria Augusta Dario+5 more
doaj +1 more source
TcI isolates of Trypanosoma cruzi exploit the antioxidant network for enhanced intracellular survival in macrophages and virulence in mice [PDF]
Trypanosoma cruzi species is categorized into six discrete typing units (TcI to TcVI) of which TcI is most abundantly noted in the sylvatic transmission cycle and considered the major cause of human disease. In our study, the TcI strains Colombiana (COL),
Basombrío, Miguel Ángel Manuel+8 more
core +2 more sources
This study evaluated the possibility of inoculation and reinoculation with a trypanosomatid isolated from bats that is morphologically, biologically and molecularly similar to Trypanosoma cruzi, to protect against infection by virulent strains.
Gabriel Antonio Nogueira Nascentes+3 more
doaj +1 more source
Perspectives on the Trypanosoma cruzi-host cell receptor interaction [PDF]
Chagas disease is caused by the parasite Trypanosoma cruzi. The critical initial event is the interaction of the trypomastigote form of the parasite with host receptors. This review highlights recent observations concerning these interactions.
A Belley+108 more
core +1 more source
INTRODUCTION: Chagas disease is caused by Trypanosoma cruzi. Wild and perianthropic mammals maintain the infection/transmission cycle, both in their natural habitat and in the peridomestic area.
Ana María Brigada+4 more
doaj +1 more source