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Chagas disease caused by the parasite Trypanosoma cruzi affects millions of people. Although its first genome dates from 2005, its complexity hindered a complete assembly and annotation. However, the new sequencing methods have improved genome annotation
Alfonso Herreros-Cabello +3 more
semanticscholar +1 more source
Chagas disease, caused by the infection with the protozoan parasite Trypanosoma cruzi, is clinically manifested in approximately one-third of infected people by inflammatory heart disease (cardiomyopathy) and, to a minor degree, gastrointestinal tract ...
Santiago J. Martinez +5 more
doaj +1 more source
Protective immunity against Trypanosoma cruzi [PDF]
Upon infection, Trypanosoma cruzi triggers a strong immune response that has both protective and pathological consequences. In this work, several important questions regarding protective immunity are reviewed.
Basombrío, Miguel Ángel Manuel +2 more
core +1 more source
Phylogenetic analysis of Bolivian bat trypanosomes of the subgenus schizotrypanum based on cytochrome B sequence and minicircle analyses. [PDF]
The aim of this study was to establish the phylogenetic relationships of trypanosomes present in blood samples of Bolivian Carollia bats. Eighteen cloned stocks were isolated from 115 bats belonging to Carollia perspicillata (Phyllostomidae) from three ...
Lineth García +5 more
doaj +1 more source
During differentiation of the dividing epimastigote to the non-dividing metacyclic trypomastigote form of the parasitic protozoan Trypanosoma cruzi there is a marked reduction in the rate of synthesis of the major proteins u- and /?-tubulin.
E. Rondinelli +5 more
semanticscholar +1 more source
Different serological cross-reactivity of Trypanosoma rangeli forms in Trypanosoma cruzi-infected patients sera [PDF]
Background American Trypanosomiasis or Chagas disease is caused by Trypanosoma cruzi which currently infects approximately 16 million people in the Americas causing high morbidity and mortality.
de Moraes, Milene H. +7 more
core +3 more sources
Perspectives on the Trypanosoma cruzi-host cell receptor interaction [PDF]
Chagas disease is caused by the parasite Trypanosoma cruzi. The critical initial event is the interaction of the trypomastigote form of the parasite with host receptors. This review highlights recent observations concerning these interactions.
A Belley +108 more
core +1 more source
INTRODUÇÃO: A transmissão transfusional da tripanossomíase americana tem-se reduzido no Brasil, com a progressiva ampliação do controle de qualidade do sangue.
Ana M. Bonametti +4 more
doaj +3 more sources
This study evaluated the possibility of inoculation and reinoculation with a trypanosomatid isolated from bats that is morphologically, biologically and molecularly similar to Trypanosoma cruzi, to protect against infection by virulent strains.
Gabriel Antonio Nogueira Nascentes +3 more
doaj +1 more source
Trypanosoma Species in Small Nonflying Mammals in an Area With a Single Previous Chagas Disease Case
Trypanosomatids are hemoflagellate parasites that even though they have been increasingly studied, many aspects of their biology and taxonomy remain unknown. The aim of this study was to investigate the Trypanosoma sp.
Maria Augusta Dario +5 more
doaj +1 more source

