Results 21 to 30 of about 143,738 (310)
Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease
bioRxiv, 2020 The protozoan Trypanosoma cruzi almost invariably establishes life-long infections in humans and other mammals, despite the development of potent host immune responses that constrain parasite numbers. The consistent, decades-long persistence of T.
Wei Wang +5 more
semanticscholar +1 more source
Acute Phase Proteins in Dogs with Natural Infection by Trypanosoma cruzi
Tropical Medicine and Infectious Disease, 2023 Acute phase proteins have been used as tools for the diagnosis, monitoring, and prognosis of several diseases in domestic animals. However, the dynamics of these proteins in infection by Trypanosoma cruzi, the causative agent of Chagas disease in dogs ...
Pilar Rivadeneira-Barreiro +8 more
doaj +1 more source
Landmarks of the Knowledge and Trypanosoma cruzi Biology in the Wild Environment
Frontiers in Cellular and Infection Microbiology, 2020 Trypanosomatids are ancient parasitic eukaryotes that still maintain prokaryotic characteristics. Trypanosoma cruzi, a primarily wild mammal parasite, infected humans already long before European colonization of the Americas. T.
A. Jansen, S. Xavier, A. L. R. Roque
semanticscholar +1 more source
Quantification of Trypanosoma cruzi in Tissue and Trypanosoma cruzi Killing Assay [PDF]
BIO-PROTOCOL, 2017 Infection with Trypanosoma cruzi causes Chagas disease. The methods provided here allow for the quantification of T. cruzi in the liver, heart, and blood of intraperitoneally-infected mice and analysis of the killing activity of the cells infected with T. cruzi in vitro.
Kiyoshi Takeda +2 more
openaire +4 more sources
Genes, 2020 Chagas disease caused by the parasite Trypanosoma cruzi affects millions of people. Although its first genome dates from 2005, its complexity hindered a complete assembly and annotation. However, the new sequencing methods have improved genome annotation
Alfonso Herreros-Cabello +3 more
semanticscholar +1 more source
The N-myristoylome of Trypanosoma cruzi [PDF]
Scientific Reports, 2016 AbstractProtein N-myristoylation is catalysed by N-myristoyltransferase (NMT), an essential and druggable target in Trypanosoma cruzi, the causative agent of Chagas’ disease. Here we have employed whole cell labelling with azidomyristic acid and click chemistry to identify N-myristoylated proteins in different life cycle stages of the parasite.
Roberts, Adam J., Fairlamb, Alan
openaire +4 more sources
Frontiers in Cellular and Infection Microbiology, 2020 Chagas disease, caused by the infection with the protozoan parasite Trypanosoma cruzi, is clinically manifested in approximately one-third of infected people by inflammatory heart disease (cardiomyopathy) and, to a minor degree, gastrointestinal tract ...
Santiago J. Martinez +5 more
doaj +1 more source
Different serological cross-reactivity of Trypanosoma rangeli forms in Trypanosoma cruzi-infected patients sera [PDF]
, 2008 Background American Trypanosomiasis or Chagas disease is caused by Trypanosoma cruzi which currently infects approximately 16 million people in the Americas causing high morbidity and mortality.
de Moraes, Milene H. +7 more
core +3 more sources
Plasminogen interaction with Trypanosoma cruzi [PDF]
Memórias do Instituto Oswaldo Cruz, 2004 The ability of Trypanosoma cruzi to interact with plasminogen, the zimogenic form of the blood serin protease plasmin, was examined. Immunohistochemistry studies revealed that both forms, epimastigotes and metacyclic trypomastigotes, were able to fix plasminogen in a lysine dependant manner.
Laura Almeida +4 more
openaire +5 more sources
Molecular epidemiology of domestic and sylvatic Trypanosoma cruzi infection in rural northwestern Argentina [PDF]
, 2008 Genetic diversity of Trypanosoma cruzi populations and parasite transmission dynamics have been well documented throughout the Americas, but few studies have been conducted in the Gran Chaco ecoregion, one of the most highly endemic areas for Chagas ...
Cardinal, Marta Victoria +8 more
core +1 more source