Results 61 to 70 of about 137,285 (295)

Astrocyte Apoptosis and HIV Replication Are Modulated in Host Cells Coinfected with Trypanosoma cruzi [PDF]

, 2017
The protozoan Trypanosoma cruzi is the etiological agent of Chagas disease. In immunosuppressed individuals, as it occurs in the coinfection with human immunodeficiency virus (HIV), the central nervous system may be affected. In this regard, reactivation
Burgos, Juan Miguel, Leguizamon, Maria Susana, Ojeda, Diego Sebastian, Pascuale, Carla Antonela, Quarleri, Jorge Fabian, Urquiza, Javier Mariano   +5 more
core   +1 more source

Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection

PLoS Pathogens, 2016
Intracellular colonization and persistent infection by the kinetoplastid protozoan parasite, Trypanosoma cruzi, underlie the pathogenesis of human Chagas disease. To obtain global insights into the T.
Yuan Li, Sheena Shah-Simpson, Kwame Okrah, A. Belew, Jungmin Choi, Kacey L. Caradonna, P. Padmanabhan, D. Ndegwa, M. Ramzi Temanni, H. C. Bravo, Najib M. El-Sayed, B. Burleigh, C. Clayton   +12 more
semanticscholar   +1 more source

Endothelial Transmigration by Trypanosoma cruzi

PLoS ONE, 2013
Chagas heart disease, the leading cause of heart failure in Latin America, results from infection with the parasite Trypanosoma cruzi. Although T. cruzi disseminates intravascularly, how the parasite contends with the endothelial barrier to escape the bloodstream and infect tissues has not been described. Understanding the interaction between T.
Cheryl L. Olson, Conrad L. Epting, Bria M. Coates, David M. Engman, David P. Sullivan, Ming Y. Makanji, Nga Du, William A. Muller   +7 more
openaire   +5 more sources

Inactive trans-sialidase expression in iTS-null Trypanosoma cruzi generates virulent trypomastigotes [PDF]

, 2017
Disclosing virulence factors from pathogens is required to better understand the pathogenic mechanisms involved in their interaction with the host. In the case of Trypanosoma cruzi several molecules are associated with virulence.
Bertelli, Adriano, Burgos, Juan Miguel, Campetella, Oscar Eduardo, Lantos, Andrés Bernardo Gabriel, Leguizamon, Maria Susana, Pascuale, Carla Antonela, Postan, Miriam   +6 more
core   +1 more source

Host-Parasite Interactions in Chagas Disease: Genetically Unidentical Isolates of a Single Trypanosoma cruzi Strain Identified In Vitro via LSSP-PCR. [PDF]

PLoS ONE, 2015
The present study aims at establishing whether the diversity in pathogenesis within a genetically diverse host population infected with a single polyclonal strain of Trypanosoma cruzi is due to selection of specific subpopulations within the strain.
Nívia Carolina Nogueira-Paiva, Paula Melo de Abreu Vieira, Larissa Maris Rezende Oliveri, Kátia da Silva Fonseca, Gwenaelle Pound-Lana, Maykon Tavares de Oliveira, Marta de Lana, Vanja Maria Veloso, Alexandre Barbosa Reis, Washington Luiz Tafuri, Cláudia Martins Carneiro   +10 more
doaj   +1 more source

Epidemiology and Molecular Typing of Trypanosoma cruzi in Naturally-Infected Hound Dogs and Associated Triatomine Vectors in Texas, USA

PLoS Neglected Tropical Diseases, 2017
Background Trypanosoma cruzi is the etiologic agent of Chagas disease throughout the Americas. Few population-level studies have examined the epidemiology of canine infection and strain types of T. cruzi that infect canines in the USA.
R. Curtis-Robles, K. Snowden, Brandon J. Dominguez, Lewis Dinges, S. Rodgers, G. Mays, S. Hamer   +6 more
semanticscholar   +1 more source

Canine Trypanosoma cruzi infection in the Bolivian Chaco [PDF]

, 2018
A cross-sectional study on Trypanosoma cruzi was carried out in 2013 to evaluate the role of dogs as possible source of infection for humans in two rural communities of the highly endemic Bolivian Chaco (Bartolo, Chuquisaca Department, n = 57 dogs; and ...
Bartoloni, Alessandro, Cancrini, Gabriella, Gabrielli, Simona, Gamboa, Herlan, Macchioni, Fabio, Rojas, Patricia, Rojo, David, Roselli, Mimmo, Spinicci, Michele, Totino, Valentina   +9 more
core   +2 more sources

Trypanosoma cruzi prevalence and clinical forms in blood donor candidates in Brazil

Revista de Saúde Pública, 2003
The prevalence and clinical forms of Trypanosoma cruzi were evaluated among blood donor candidates attended at a general hospital in Rio de Janeiro, Brazil, from January 1997 to April 1999.
Silveira H J, Mozart O N, Norberg A N, Pile E A   +3 more
doaj   +3 more sources

The Complement System: A Prey of Trypanosoma cruzi

Frontiers in Microbiology, 2017
Trypanosoma cruzi is a protozoan parasite known to cause Chagas disease (CD), a neglected sickness that affects around 6–8 million people worldwide. Originally, CD was mainly found in Latin America but more recently, it has been spread to countries in ...
K. Lidani, Lorena Bavia, A. Ambrosio, I. D. de Messias-Reason   +3 more
semanticscholar   +1 more source

Trypanosomes are monophyletic: evidence from genes for glyceraldehyde phosphate dehydrogenase and small subunit ribosomal RNA.

, 2004
The genomes of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major have been sequenced, but the phylogenetic relationships of these three protozoa remain uncertain.
Gaunt, Michael W, Gibson, Wendy C, Gidley, Jennifer, Hamilton, Patrick B, Stevens, Jamie R   +4 more
core   +1 more source