Results 11 to 20 of about 1,058 (176)

Exploring Trypanosoma cruzi transmission dynamics in an acute Chagas disease outbreak using next-generation sequencing [PDF]

Parasites & Vectors
Background Chagas disease (CD), caused by Trypanosoma cruzi, poses a major global public health challenge. Although vector-borne transmission is the primary mode of infection, oral transmission is increasingly concerning. Methods This study utilized long-
Lissa Cruz-Saavedra, Carlos Ospina, Stivenn A. Gutiérrez, Jeiczon Jaimes-Dueñez, Omar Cantillo-Barraza, Carolina Hernández, Francisco Álvarez, María Blanco, Bernardo Leal, Lida Martínez, Manuel Medina, Mabel Medina, Silvia Valdivieso, Lauren Natalia Ramirez Celis, Luz H. Patiño, Juan David Ramírez   +15 more
doaj   +2 more sources

Parasite-mediated interactions within the insect vector: Trypanosoma rangeli strategies [PDF]

Parasites & Vectors, 2012
Trypanosoma rangeli is a protozoan that is non-pathogenic for humans and other mammals but causes pathology in the genus Rhodnius. T. rangeli and R.
Garcia Eloi S, Castro Daniele P, Figueiredo Marcela B, Azambuja Patrícia   +3 more
doaj   +2 more sources

Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis

Acta Crystallographica Section D, Volume 79, Issue 6, Page 518-530, June 2023., 2023
Biochemical and structural analyses of cysteine synthase, the key enzyme in cysteine biosynthesis, from the protozoan pathogens Trypanosoma cruzi, T. theileri and Leishmania infantum are presented. This enzyme is a potential drug target for neglected tropical diseases such as Chagas disease and leishmaniasis.Chagas disease is a neglected tropical ...
Kate Sowerby, Stefanie Freitag-Pohl, Ana Milena Murillo, Ariel Mariano Silber, Ehmke Pohl   +4 more
wiley   +1 more source

Genome Assembly and Genome Annotation of Leishmania martiniquensis Isolated from a Leishmaniasis Patient in Thailand

Journal of Parasitology Research, Volume 2022, Issue 1, 2022., 2022
Leishmaniasis is a parasitic disease caused by Leishmania spp. with worldwide distribution. Autochthonous leishmaniasis has been reported to result from the infection by Leishmania martiniquensis in Thailand. This species was isolated in culture and subjected to high‐throughput whole‐genome sequencing.
Songtham Anuntakarun, Atchara Phumee, Vorthon Sawaswong, Kesmanee Praianantathavorn, Witthaya Poomipak, Rungrat Jitvaropas, Padet Siriyasatien, Sunchai Payungporn, Kwang Poo Chang   +8 more
wiley   +1 more source

Administration of artinm lectin reduces the severity of the acute phase infection with Trypanosoma cruzi

FASEB BioAdvances, Volume 3, Issue 5, Page 295-304, May 2021., 2021
Abstract The acute phase of experimental Trypanosoma cruzi infection is associated with a strong inflammatory reaction, physiological changes, amastigote nests in tissues, and hematological alterations. ArtinM, a lectin extracted from Artocarpus heterophyllus seeds, is a homotetramer exhibiting immunomodulatory properties that promotes Th1 immune ...
Camila Botelho Miguel, Thiago Aparecido da silva, Wellington Francisco Rodrigues, Patrícia Kellen Martins Oliveira‐Brito, Maria Cristina Roque‐Barreira, Javier Emílio Lazo‐Chica   +5 more
wiley   +1 more source

Protein Profiles of Trypanosoma cruzi and Trypanosoma rangeli [PDF]

Parasitología latinoamericana, 2004
Trypanosoma cruzi, is a protozoan parasite, which has a close phylogenetic relationship with Trypanosoma rangeli that is not pathogenic for the vertebrate host. Both parasites have antigenic similarity, they have different and complex total protein profiles according to their morphological and physiological stage epimastigotes or trypomastigotes ...
MEJÍA, ASTRID J, PALÁU, MARÍA TERESA, ZÚÑIGA, CLAUDIO A   +2 more
openaire   +2 more sources

Trypanosoma rangeli and Trypanosoma cruzi: cross-reaction among their immunogenic components [PDF]

Memórias do Instituto Oswaldo Cruz, 1996
It has been demonstrated that immuno-modu-lating mechanisms induced by epimastigotes ofTrypanosoma rangeli, an assumed harmless hu-man parasite, may have relevance to protectionagainst Trypanosoma cruzi, the causative organ-ism of Chagas’ disease (B Basso et al. 1991 Am JTrop Med Hyg 44: 413-419).
A. Saldaña, O. E. Sousa
openaire   +4 more sources

Extent of polymorphism and selection pressure on the Trypanosoma cruzi vaccine candidate antigen Tc24

Evolutionary Applications, Volume 13, Issue 10, Page 2663-2672, December 2020., 2020
Abstract Introduction Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is a major public health problem in the Americas, and existing drugs have severe limitations. In this context, a vaccine would be an attractive alternative for disease control.
Audrey Arnal, Liliana Villanueva‐Lizama, Christian Teh‐Poot, Claudia Herrera, Eric Dumonteil   +4 more
wiley   +1 more source

The zinc finger proteins ZC3H20 and ZC3H21 stabilise mRNAs encoding membrane proteins and mitochondrial proteins in insect‐form Trypanosoma brucei

Molecular Microbiology, Volume 113, Issue 2, Page 430-451, February 2020., 2020
African trypanosomes are parasites that can grow in the blood of mammals, as "bloodstream forms", and the digestive system of Tsetse flies as "procyclic forms". ZC3H20 and ZC3H21 are related trypanosome proteins that can bind to mRNA. They are absent in growing bloodstream forms, but present in procyclic forms.
Bin Liu, Kevin Kamanyi Marucha, Christine Clayton   +2 more
wiley   +1 more source

Studies on Trypanosoma rangeli Tejera 1920: VI. Developmental pattern in the haemolymph of Rhodnius prolixus

Memorias do Instituto Oswaldo Cruz, 1983
The morphological sequence of Trypanosoma rangeli development in the body cavity of Rhodnius prolixus is described. The metacyclic trypanosome is the product of successive division and transformation during the intra and extracellular development in the ...
N. Añez
doaj   +1 more source