Results 31 to 40 of about 1,058 (176)

Vaccination with epimastigotes of different strains of Trypanosoma rangeli protects mice against Trypanosoma cruzi infection

Memorias do Instituto Oswaldo Cruz, 2008
In our laboratory, we have developed a model of vaccination in mice with Trypanosoma rangeli, a non-pathogenic parasite that shares many antigens with Trypanosoma cruzi. The vaccinated mice were protected against infection with virulent T. cruzi.
Beatriz Basso, Edgardo Moretti, Ricardo Fretes   +2 more
doaj   +1 more source

La región intergénica del gen H2A apoya las subpoblaciones KP1(-) y KP1(+) de Trypanosoma rangeli

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. Con base en la amplificación del ADN de los minicírculos del cinetoplasto y de los genes miniexón, Trypanosoma rangeli ha sido clasificado en las subpoblaciones KP1(-) y KP1(+). Objetivo.
Brian Alejandro Suárez, Claudia Liliana Cuervo, Concepción Judith Puerta   +2 more
doaj   +1 more source

Experimental Vaccines against Chagas Disease: A Journey through History

Journal of Immunology Research, Volume 2015, Issue 1, 2015., 2015
Chagas disease, or American trypanosomiasis, which is caused by the protozoan parasite Trypanosoma cruzi, is primarily a vector disease endemic in 21 Latin American countries, including Mexico. Although many vector control programs have been implemented, T. cruzi has not been eradicated. The development of an anti‐T.
Olivia Rodríguez-Morales, Víctor Monteón-Padilla, Silvia C. Carrillo-Sánchez, Martha Rios-Castro, Mariana Martínez-Cruz, Alejandro Carabarin-Lima, Minerva Arce-Fonseca, Xiao-Feng Yang   +7 more
wiley   +1 more source

Trypanosoma rangeli protein tyrosine phosphatase is associated with the parasite's flagellum

Memorias do Instituto Oswaldo Cruz, 2012
Protein tyrosine phosphatases (PTPs) play an essential role in the regulation of cell differentiation in pathogenic trypanosomatids. In this study, we describe a PTP expressed by the non-pathogenic protozoan Trypanosoma rangeli (TrPTP2).
Elisa Beatriz Prestes, Ethel Bayer-Santos, Patrícia Hermes Stoco, Thaís Cristine Marques Sincero, Glauber Wagner, Adriana Umaki, Stenio Perdigão Fragoso, Juliano Bordignon, Mário Steindel, Edmundo Carlos Grisard   +9 more
doaj   +1 more source

Trypanosoma cruzi Infection and Host Lipid Metabolism

Mediators of Inflammation, Volume 2014, Issue 1, 2014., 2014
Trypanosoma cruzi is the causative agent of Chagas disease. Approximately 8 million people are thought to be affected worldwide. Several players in host lipid metabolism have been implicated in T. cruzi‐host interactions in recent research, including macrophages, adipocytes, low density lipoprotein (LDL), low density lipoprotein receptor (LDLR), and ...
Qianqian Miao, Momar Ndao, Marcelo T. Bozza   +2 more
wiley   +1 more source

Rhodnius stali: new vector infected by Trypanosoma rangeli (Kinetoplastida, Trypanosomatidae)

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION Rhodnius stali infection by Trypanosoma rangeli is reported in this study for the first time. METHODS The triatomines were collected from the campus of the Federal University of Acre in Rio Branco, Acre, Brazil.
Gabriela Vieira de Souza Castro, Mariane Albuquerque Lima Ribeiro, Leandro José Ramos, Jader de Oliveira, João Aristeu da Rosa, Luis Marcelo Aranha Camargo, Dionatas Ulises de Oliveira Meneguetti   +6 more
doaj   +1 more source

Detection of Trypanosoma cruzi and Trypanosoma rangeli infection in triatomine vectors by amplification of the histone H2A/SIRE and the sno-RNA-C11 genes Detecção da infecção por Trypanosoma cruzi e Trypanosoma rangeli em vetores triatomíneos através da amplificação dos gens de histona H2A/SIRE e sno-RNA-C11

Revista do Instituto de Medicina Tropical de São Paulo, 2007
Trypanosoma rangeli is non pathogenic for humans but of important medical and epidemiological interest because it shares vertebrate hosts, insect vectors, reservoirs and geographic areas with T. cruzi, the etiological agent of Chagas disease.
Paula Ximena Pavia, Gustavo Adolfo Vallejo, Marleny Montilla, Rubén Santiago Nicholls, Concepción Judith Puerta   +4 more
doaj   +1 more source

Partial Purification of Integral Membrane Antigenic Proteins from Trypanosoma evansi That Display Immunological Cross‐Reactivity with Trypanosoma vivax

Journal of Parasitology Research, Volume 2014, Issue 1, 2014., 2014
Trypanosoma evansi and Trypanosoma vivax, which are the major causative agents of animal trypanosomosis in Venezuela, have shown a very high immunological cross‐reactivity. Since the production of T. vivax antigens is a limiting factor as this parasite is difficult to propagate in experimental animal models, our goal has been to identify and isolate ...
Norma P. Velásquez, Rocío E. Camargo, Graciela L. Uzcanga, José Bubis, D. S. Lindsay   +4 more
wiley   +1 more source

Vaccination with Trypanosoma rangeli modulates the profiles of immunoglobulins and IL-6 at local and systemic levels in the early phase of Trypanosoma cruzi experimental infection

Memorias do Instituto Oswaldo Cruz, 2011
In America, there are two species of Trypanosoma that can infect humans: Trypanosoma cruzi, which is responsible for Chagas disease and Trypanosoma rangeli, which is not pathogenic. We have developed a model of vaccination in mice with T.
Vanina Marini, Edgardo Moretti, Daniela Bermejo, Beatriz Basso   +3 more
doaj   +1 more source

Genetic Structure and Expression of the Surface Glycoprotein GP82, the Main Adhesin of Trypanosoma cruzi Metacyclic Trypomastigotes

The Scientific World Journal, Volume 2013, Issue 1, 2013., 2013
T. cruzi improves the likelihood of invading or adapting to the host through its capacity to present a large repertoire of surface molecules. The metacyclic stage‐specific surface glycoprotein GP82 has been implicated in host cell invasion. GP82 is encoded by multiple genes from the trans‐sialidase superfamily.
Paulo Roberto Ceridorio Correa, Esteban Mauricio Cordero, Luciana Girotto Gentil, Ethel Bayer-Santos, José Franco da Silveira, S. Amaral Gonçalves da Silva, P. M. L. Dutra, P. Grellier, J. Martins de Santana   +8 more
wiley   +1 more source