Results 11 to 20 of about 5,899 (137)

Antileishmanial Activity of 4,8-Dimethoxynaphthalenyl Chalcones on Leishmania amazonensis

Antibiotics, 2022
Leishmaniasis is a neglected tropical disease caused by Leishmania species. Available therapeutic options have several limitations. The drive to develop new, more potent, and selective antileishmanial agents is thus a major goal.
Kaio Maciel de Santiago-Silva, Bruna Taciane da Silva Bortoleti, Laudicéa do Nascimento Oliveira, Fernanda Lima de Azevedo Maia, Joyce Cristina Castro, Ivete Conchon Costa, Danielle Bidóia Lazarin, James L. Wardell, Solange M. S. V. Wardell, Magaly Girão Albuquerque, Camilo Henrique da Silva Lima, Wander Rogério Pavanelli, Marcelle de Lima Ferreira Bispo, Raoni Schroeder B. Gonçalves   +13 more
doaj   +1 more source

Detection of Lotmaria passim, Crithidia mellificae and Replicative Forms of Deformed Wing Virus and Kashmir Bee Virus in the Small Hive Beetle (Aethina tumida)

Pathogens, 2021
Knowledge regarding the honey bee pathogens borne by invasive bee pests remains scarce. This investigation aimed to assess the presence in Aethina tumida (small hive beetle, SHB) adults of honey bee pathogens belonging to the following groups: (i ...
Antonio Nanetti, James D. Ellis, Ilaria Cardaio, Giovanni Cilia   +3 more
doaj   +1 more source

Iron Uptake Controls Trypanosoma cruzi Metabolic Shift and Cell Proliferation

Antioxidants, 2023
(1) Background: Ionic transport in Trypanosoma cruzi is the object of intense studies. T. cruzi expresses a Fe-reductase (TcFR) and a Fe transporter (TcIT).
Claudia F. Dick, Carolina L. Alcantara, Luiz F. Carvalho-Kelly, Marco Antonio Lacerda-Abreu, Narcisa L. Cunha-e-Silva, José R. Meyer-Fernandes, Adalberto Vieyra   +6 more
doaj   +1 more source

Morphological and molecular description of Blastocrithidia cyrtomeni sp. nov. (Kinetoplastea: Trypanosomatidae) associated with Cyrtomenus bergi Froeschner (Hemiptera: Cydnidae) from Colombia

Memorias do Instituto Oswaldo Cruz, 2011
A new trypanosomatid species, Blastocrithidia cyrtomeni, is herein described using morphological and molecular data. It was found parasitising the alimentary tract of the insect host Cyrtomenus bergi, a polyphagous pest. The morphology of B.
Ana Milena Caicedo, Gerardo Gallego, Jaime Eduardo Muñoz, Harold Suárez, Gerardo Andrés Torres, Humberto Carvajal, Fanny Caro De Carvajal, Andrés Mauricio Posso, Dmitriv Maslov, James Montoya-Lerma   +9 more
doaj   +1 more source

Mechanisms of growth inhibition of Phytomonas serpens by the alkaloids tomatine and tomatidine

Memorias do Instituto Oswaldo Cruz, 2015
Phytomonas serpens are flagellates in the family Trypanosomatidae that parasitise the tomato plant (Solanum lycopersicum L.), which results in fruits with low commercial value.
Jorge Mansur Medina, Juliany Cola Fernandes Rodrigues, Otacilio C Moreira, Geórgia Atella, Wanderley de Souza, Hector Barrabin   +5 more
doaj   +1 more source

Energy metabolism in Trypanosoma cruzi: the validated and putative bioenergetic and carbon sources

mBio
Trypanosoma cruzi, along with Trypanosoma brucei and over 20 species of the genus Leishmania, constitutes a group of human pathogenic flagellated protists collectively called the “TriTryp,” posing among the best-studied protists.
Mayke B. Alencar, Sabrina Marsiccobetre, Ana C. Mengarda, Maria Sol Ballari, Ariel M. Silber   +4 more
doaj   +1 more source

The role of l-serine and l-threonine in the energy metabolism and nutritional stress response of Trypanosoma cruzi

mSphere
l-Serine and l-threonine have versatile roles in metabolism. In addition to their use in protein synthesis, these amino acids participate in the biosynthesis pathways of other amino acids and even phospholipids.
Mayke Bezerra Alencar, Richard Marcel Bruno Moreira Girard, Marcell Crispim, Carlos Gustavo Baptista, Marc Biran, Frederic Bringaud, Ariel Mariano Silber   +6 more
doaj   +1 more source

Cell Cycle-Dependent Flagellar Disassembly in a Firebug Trypanosomatid Leptomonas pyrrhocoris

mBio, 2019
Current understanding of flagellum/cilium length regulation focuses on a few model organisms with flagella of uniform length. Leptomonas pyrrhocoris is a monoxenous trypanosomatid parasite of firebugs. When cultivated in vitro, L.
Cynthia Y. He, Adarsh Singh, Vyacheslav Yurchenko   +2 more
doaj   +1 more source

Current Status of Regulatory Non-Coding RNAs Research in the Tritryp

Non-Coding RNA, 2022
Trypanosomatids are protozoan parasites that cause devastating vector-borne human diseases. Gene expression regulation of these organisms depends on post-transcriptional control in responding to diverse environments while going through multiple ...
Rafael Sebastián Fort, Santiago Chavez, Juan M. Trinidad Barnech, Carolina Oliveira-Rizzo, Pablo Smircich, José Roberto Sotelo-Silveira, María Ana Duhagon   +6 more
doaj   +1 more source

Assessment of Cross-Reactivity of Chimeric Trypanosoma cruzi Antigens with Crithidia sp. LVH-60A: Implications for Accurate Diagnostics

Diagnostics, 2023
This study focuses on developing accurate immunoassays for diagnosing Chagas disease (CD), a challenging task due to antigenic similarities between Trypanosoma cruzi and other parasites, leading to cross-reactivity.
Emily F. Santos, Ramona T. Daltro, Carlos G. Regis-Silva, Tycha B. S. Pavan, Fabrícia A. de Oliveira, Ângela M. da Silva, Roque P. Almeida, Noilson L. S. Gonçalves, Daniel D. Sampaio, Faber N. Santos, Fabricio K. Marchini, Paola A. F. Celedon, Nilson I. T. Zanchin, Fred L. N. Santos   +13 more
doaj   +1 more source