Results 11 to 20 of about 9,059 (176)

The surface charge of trypanosomatids

open access: yesAnais da Academia Brasileira de Ciências, 2002
The surface charge of trypanosomatids was evaluated by means of the binding of cationic particles, as visualized by electron microscopy and by direct measurements of the electrophoretic mobility of cells.
SOUTO-PADRÓN THAÏS
doaj   +1 more source

Targeting Trypanothione Metabolism in Trypanosomatids [PDF]

open access: yesMolecules
Infectious diseases caused by trypanosomatids, including African trypanosomiasis (sleeping sickness), Chagas disease, and different forms of leishmaniasis, are Neglected Tropical Diseases affecting millions of people worldwide, mainly in vulnerable ...
María-Cristina González-Montero   +6 more
doaj   +3 more sources

Codon usage suggests that translational selection has a major impact on protein expression in trypanosomatids [PDF]

open access: yesBMC Genomics, 2008
Background Different proteins are required in widely different quantities to build a living cell. In most organisms, transcription control makes a major contribution to differential expression. This is not the case in trypanosomatids where most genes are
Horn David
doaj   +2 more sources

Mitochondrial translation in trypanosomatids: a novel target for chemotherapy? [PDF]

open access: yes, 2011
Trypanosomatids cause widespread disease in humans and animals. Treatment of many of these diseases is hampered by the lack of efficient and safe drugs. New strategies for drug development are therefore urgently needed.
Moritz Niemann   +5 more
core   +2 more sources

Trypanosomatids are common and diverse parasites of Drosophila [PDF]

open access: yes, 2011
Drosophila melanogaster is an important model system of immunity and parasite resistance, yet most studies use parasites that do not naturally infect this organism.
Wilfert, L.   +9 more
core   +1 more source

Iron metabolism in trypanosomatids, and its crucial role in infection. [PDF]

open access: yes, 2010
Iron is almost ubiquitous in living organisms due to the utility of its redox chemistry. It is also dangerous as it can catalyse the formation of reactive free radicals - a classical double-edged sword.
Taylor, MC, Kelly, JM
core   +1 more source

Current Status of Regulatory Non-Coding RNAs Research in the Tritryp

open access: yesNon-Coding RNA, 2022
Trypanosomatids are protozoan parasites that cause devastating vector-borne human diseases. Gene expression regulation of these organisms depends on post-transcriptional control in responding to diverse environments while going through multiple ...
Rafael Sebastián Fort   +6 more
doaj   +1 more source

Ribosomes from Trypanosomatids: Unique Structural and Functional Properties [PDF]

open access: yes, 2012
Trypanosomatids are a monophyletic group of protozoa that diverged early from the eukaryotic lineage, constituting valuable model organisms for studying variability in different highly conserved processes including protein synthesis.
Lapadula, Walter Jesús   +7 more
core   +1 more source

Ion channels in pathogenic trypanosomatids.

open access: yes, 2022
Ion channels in pathogenic trypanosomatids.
Veronica Jimenez (106317)   +1 more
core   +1 more source

Assessment of Cross-Reactivity of Chimeric Trypanosoma cruzi Antigens with Crithidia sp. LVH-60A: Implications for Accurate Diagnostics

open access: yesDiagnostics, 2023
This study focuses on developing accurate immunoassays for diagnosing Chagas disease (CD), a challenging task due to antigenic similarities between Trypanosoma cruzi and other parasites, leading to cross-reactivity.
Emily F. Santos   +13 more
doaj   +1 more source

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