Results 41 to 50 of about 9,059 (176)
Kinase families identified in trypanosomatids.
, 2013 Kinase families identified in trypanosomatids.
Maria Carolina Elias (243026) +39 more
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Editosome Accessory Factors KREPB9 and KREPB10 in Trypanosoma brucei [PDF]
, 2012 Multiprotein complexes, called editosomes, catalyze the uridine insertion and deletion RNA editing that forms translatable mitochondrial mRNAs in kinetoplastid parasites.
Acestor, Nathalie +5 more
core +1 more source
, 2023 African sleeping sickness, Chagas disease, and leishmaniasis are life-threatening diseases that together affect millions of people around the world and are caused by different members of the protozoan family Trypanosomatidae.
Anders Hofer +2 more
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An improved silver staining procedure for schizodeme analysis in polyacrylamide gradient gels
Memorias do Instituto Oswaldo Cruz, 1990 A simple protocol is described for the silver staining of polyacrylamide gradient gels used for the separation of restriction fragments of kinetoplast DNA [schizodeme analysis of trypanosomatids (Morel et al., 1980)]. The method overcomes the problems of
Antonio M. Gonçalves +2 more
doaj +1 more source
ChemMedChem, Volume 21, Issue 18, 28 September 2026.This review outlines a pioneering strategy to inhibit Leishmania infantum trypanothione reductase by disrupting its dimer interface. From peptides to small‐molecule proteomimetics, multiple chemotypes achieved potent enzymatic inhibition and notable cellular antileishmanial activity, highlighting a new therapeutic paradigm.
María‐José Camarasa +3 more
wiley +1 more source
Cytokinesis in trypanosomatids
, 2007 The process of cytokinesis, where the cytoplasm of one cell is divided to produce two daughter cells, is intricate in trypanosomatids because of the requirement to replicate and segregate a number of single copy organelles, including the nucleus ...
Hammarton, Tansy C. +2 more
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Potential Drug Targets in the Pentose Phosphate Pathway of Trypanosomatids [PDF]
, 2018 The trypanosomatids, Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp, are causative agents of important human diseases such as African sleeping sickness, Chagas’ disease and Leishmaniasis, respectively.
Inês Loureiro +17 more
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The surface charge of trypanosomatids of the genus trypanosoma
Memorias do Instituto Oswaldo Cruz, 1990 Cell electrophoresis was used for determionation of the electrophoretic mobility (EPM) of epimastigo and trypamastigote forms of several isolates of Trypanosoma cruzi and some stocks of other members of the Schizotrypanum subgenus, such as T. dionisii, T.
Thaís Souto Padrón +2 more
doaj +1 more source
ChemMedChem, Volume 21, Issue 17, 14 September 2026.Evaluation of two libraries of peptoid‐based compounds for inhibitory activity against PfA‐M1 from Plasmodium falciparum, TcLAP from Trypanosoma cruzi, and LmLAP from Leishmania major reveals the crucial role of hydrophobic interactions in the inhibition process of these parasite metallo‐aminopeptidases.
Mirta Elisa Aguado +16 more
wiley +1 more source
Cyclic AMP Signaling in Trypanosomatids
, 2000 Curative interference with signal transduction pathways is a spectacularly successful concept in many domains of modern pharmacology; indeed, the ‘wonder drug’ Viagra is but a humble inhibitor of a cyclic GMP (cGMP)-specific phosphodiesterase and, thus ...
T Seebeck +3 more
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