Results 31 to 40 of about 9,059 (176)

Cell Cycle-Dependent Flagellar Disassembly in a Firebug Trypanosomatid Leptomonas pyrrhocoris

open access: yesmBio, 2019
Current understanding of flagellum/cilium length regulation focuses on a few model organisms with flagella of uniform length. Leptomonas pyrrhocoris is a monoxenous trypanosomatid parasite of firebugs. When cultivated in vitro, L.
Cynthia Y. He   +2 more
doaj   +1 more source

Unshared on the top: strong segregation of pathogen communities between western honey bees and wild bees in a retreating glacier foreland

open access: yesOikos, EarlyView.
Shared flowers can facilitate pathogen transmission between managed honey bees and wild bees, yet this process remains poorly understood in ecosystems undergoing rapid environmental change. Using a glacier foreland in Switzerland, we present the first study on how glacier retreat stages and bee life‐history traits influence pathogen occurrence across ...
Andrea Ferrari   +6 more
wiley   +1 more source

Apoptosis in parasites and parasite-induced apoptosis in the host immune system: a new approach to parasitic diseases

open access: yesBrazilian Journal of Medical and Biological Research, 1999
Apoptosis, a form of programmed cell death (PCD), has been described as essential for normal organogenesis and tissue development, as well as for the proper function of cell-renewal systems in adult organisms.
M.A. Barcinski, G.A. DosReis
doaj   +1 more source

Common pathways and outliers in glucose catabolism across Trypanosomatidae

open access: yesThe FEBS Journal, EarlyView.
Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes   +5 more
wiley   +1 more source

Leptoconops nosopheris sp. n. (Diptera: Ceratopogonidae) and Paleotrypanosoma burmanicus gen. n., sp. n. (Kinetoplastida: Trypanosomatidae), a biting midge - trypanosome vector association from the Early Cretaceous

open access: yesMemorias do Instituto Oswaldo Cruz, 2008
Leptoconops nosopheris sp. n. (Diptera: Ceratopogonidae) is described from a blood-filled female biting midge in Early Cretaceous Burmese amber. The new species is characterized by a very elongate terminal flagellomere, elongate cerci, and an indistinct ...
George Poinar Jr.
doaj   +1 more source

Iron Uptake Controls Trypanosoma cruzi Metabolic Shift and Cell Proliferation

open access: yesAntioxidants, 2023
(1) Background: Ionic transport in Trypanosoma cruzi is the object of intense studies. T. cruzi expresses a Fe-reductase (TcFR) and a Fe transporter (TcIT).
Claudia F. Dick   +6 more
doaj   +1 more source

Trypanosomal MICOS Is Assembled on Non‐Respiring Mitochondrial Crista Precursors and Associates With Two Integral Microproteins

open access: yesMolecular Microbiology, EarlyView.
The mitochondrial membrane‐shaping machinery MICOS is assembled surprisingly early during the life cycle of Trypanosoma brucei, before the mitochondrion acquires its mature architecture or full respiratory capacity. Our study also identifies two previously uncharacterized proteins associated with MICOS, providing new insight into the early organization
Michala Boudová   +5 more
wiley   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 10, Page 1686-1701, October 2026.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva   +10 more
wiley   +1 more source

Telomere biology of trypanosomatids: more questions than answers

open access: yes, 2015
Trypanosomatids, are severe pathogens in developing countries, where they affect both humans and domestic animals. Factors intrinsic to the host,the toxicity or subcurative effects of the available antiparasite medication and the low perspective of ...
Cano, MIN
core   +2 more sources

Validating Wing Biopsies for Blood‐Borne Pathogen Characterization in Bats

open access: yesMolecular Ecology, Volume 35, Issue 19, October 2026.
ABSTRACT Wildlife surveillance is critical for tracking disease emergence, characterizing pathogen diversity, and assessing spillover risks. Blood‐borne pathogens are of particular interest for such efforts due to their global distribution, broad host taxa, and zoonotic potential.
Molly C. Simonis   +9 more
wiley   +1 more source

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