Results 41 to 50 of about 54,903 (309)
The trypanosome flagellum [PDF]
Journal of Cell Science, 2003 African Trypanosomes are flagellated protozoan parasites that cause sleeping sickness in humans and Nagana in cattle. During its life cycle, Trypanosoma brucei alternates between an insect vector (tsetse fly) and a mammalian host.
Vaughan, S, Gull, K
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Nitroheterocyclic drug resistance mechanisms in Trypanosoma brucei [PDF]
, 2015 OBJECTIVES: The objective of this study was to identify the mechanisms of resistance to nifurtimox and fexinidazole in African trypanosomes. METHODS: Bloodstream-form Trypanosoma brucei were selected for resistance to nifurtimox and fexinidazole by ...
Berriman, Matthew +5 more
core +3 more sources
Genetic exchange in Trypanosoma brucei: evidence for mating prior to metacyclic stage development [PDF]
, 2005 It is well established that genetic exchange occurs between Trypanosoma brucei parasites when two stocks are used to infect tsetse flies under laboratory conditions and a number of such crosses have been undertaken.
Alison Tweedie +22 more
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Molecules, 2016 Glucose-6-phosphate dehydrogenase (G6PDH) plays a housekeeping role in cell metabolism by generating reducing power (NADPH) and fueling the production of nucleotide precursors (ribose-5-phosphate).
Cecilia Ortiz +5 more
doaj +1 more source
Molecular identification of different trypanosome species and subspecies in tsetse flies of northern Nigeria [PDF]
, 2016 Background: Animal African Trypanosomiasis (AAT) is caused by several species of trypanosomes including Trypanosoma congolense, T. vivax, T. godfreyi, T. simiae and T. brucei. Two of the subspecies of T. brucei also cause Human African Trypanosomiasis.
Ciosi, Marc +8 more
core +1 more source
The trypanosomal transferrin receptor of trypanosoma brucei : a review [PDF]
, 2019 Iron is an essential element for life. Its uptake and utility requires a careful balancing with its toxic capacity, with mammals evolving a safe and bio-viable means of its transport and storage. This transport and storage is also utilized as part of the
Kariuki, Christopher K. +2 more
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Evolution of mitochondrial protein import – lessons from trypanosomes
Biological chemistry, 2019 The evolution of mitochondrial protein import and the systems that mediate it marks the boundary between the endosymbiotic ancestor of mitochondria and a true organelle that is under the control of the nucleus.
A. Schneider
semanticscholar +1 more source
Activation of endocytosis as an adaptation to the mammalian host by trypanosomes [PDF]
, 2007 Immune evasion in African trypanosomes is principally mediated by antigenic variation, but rapid internalization of surface-bound immune factors may contribute to survival.
Field, Mark C +4 more
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Imaging
Parasite Immunology, 2013 SummaryTrypanosoma brucei are extracellular kinetoplastid parasites transmitted by the blood‐sucking tsetse fly. They are responsible for the fatal disease human African trypanosomiasis (HAT), also known as sleeping sickness. In late‐stage infection, trypanosomes cross the blood–brain barrier (BBB) and invade the central nervous system (CNS) invariably
MacLean, L. +3 more
openaire +3 more sources
Microfluidics-based approaches to the isolation of African trypanosomes [PDF]
, 2017 African trypanosomes are responsible for significant levels of disease in both humans and animals. The protozoan parasites are free-living flagellates, usually transmitted by arthropod vectors, including the tsetse fly. In the mammalian host they live in
Barrett, Michael P. +6 more
core +3 more sources