Results 41 to 50 of about 39,396 (251)
Independence from kinetoplast DNA maintenance and expression is associated with multi-drug resistance in Trypanosoma brucei in vitro [PDF]
, 2014 It is well known that several antitrypanosomatid drugs accumulate in the parasite's mitochondrion, where they often bind to the organellar DNA, the kinetoplast.
A. Schnaufer +32 more
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Acidocalcisome-Mitochondrion Membrane Contact Sites in Trypanosoma brucei
Pathogens, 2018 Membrane contact sites are regions of close apposition between two organelles, typically less than 30 nanometers apart, that facilitate transfer of biomolecules.
Srinivasan Ramakrishnan +2 more
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(E)-5-(Methoxyimino)-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one
Molbank, 2021 (E)-5-(Methoxyimino)-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one was prepared by a condensation reaction from 3,4-dihydro-1H-benzo[b]azepin-2,5-dione and O-methylhydroxylamine.
Irina Ihnatenko +2 more
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Parasite motility is critical for virulence of African trypanosomes. [PDF]
, 2018 African trypanosomes, Trypanosoma brucei spp., are lethal pathogens that cause substantial human suffering and limit economic development in some of the world's most impoverished regions.
Geng, Quanjie +6 more
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The evolution of pathogenic trypanosomes [PDF]
Cadernos de Saúde Pública, 1999 In the absence of a fossil record, the evolution of protozoa has until recently largely remained a matter for speculation. However, advances in molecular methods and phylogenetic analysis are now allowing interpretation of the "history written in the genes".
Stevens, JR, Gibson, WC
openaire +8 more sources
Tropical Medicine and Infectious Disease, 2023 Tsetse flies are obligate hematophagous vectors of animal and human African trypanosomosis. They cyclically transmit pathogenic Trypanosoma species. The endosymbiont Sodalis glossinidius is suggested to play a role in facilitating the susceptibility of ...
Simegnew Adugna Kallu +4 more
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The trypanosomal transferrin receptor of trypanosoma brucei : a review [PDF]
, 2019 Iron is an essential element for life. Its uptake and utility requires a careful balancing with its toxic capacity, with mammals evolving a safe and bio-viable means of its transport and storage. This transport and storage is also utilized as part of the
Kariuki, Christopher K. +2 more
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Telomeres, tethers and trypanosomes [PDF]
Nucleus, 2012 Temporal and spatial organization of the nucleus is critical for the control of transcription, mRNA processing and the assembly of ribosomes. This includes the occupancy of specific territories by mammalian chromosomes, the presence of subnuclear compartments such as the nucleolus and Cajal bodies and the division of chromatin between active and ...
Field, Mark C. +4 more
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Frontiers in Chemical BiologyIntroductionIn vivo imaging technology based on bioluminescence has contributed to the study of different pathophysiological conditions involving inherited or transmissible diseases.
Diego Benítez +4 more
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The long and winding road of reverse genetics in Trypanosoma cruzi
Microbial Cell, 2021 Trypanosomes are early divergent protists with distinctive features among eukaryotic cells. Together with Trypanosoma brucei and Leishmania spp., Trypanosoma cruzi has been one of the most studied members of the group.
Miguel A. Chiurillo, Noelia Lander
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