Results 51 to 60 of about 39,396 (251)
Development of bioluminescent reporter Trypanosoma cruzi and bioassay for compound screening
Frontiers in Chemical BiologyTrypanosoma cruzi is the etiologic agent of Chagas’ disease, a debilitating and mortal zoonotic illness that threatens the lives of several millions of people in the American continent. The acute phase is underdiagnosed and there is no curative treatment
Cristina Quiroga +6 more
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Structure, Properties, and Function of Glycosomes in Trypanosoma cruzi
Frontiers in Cellular and Infection Microbiology, 2020 Glycosomes are peroxisome-related organelles that have been identified in kinetoplastids and diplonemids. The hallmark of glycosomes is their harboring of the majority of the glycolytic enzymes.
Wilfredo Quiñones +5 more
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Nitroheterocyclic drug resistance mechanisms in Trypanosoma brucei [PDF]
, 2015 OBJECTIVES: The objective of this study was to identify the mechanisms of resistance to nifurtimox and fexinidazole in African trypanosomes. METHODS: Bloodstream-form Trypanosoma brucei were selected for resistance to nifurtimox and fexinidazole by ...
Berriman, Matthew +5 more
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mBio, 2021 In the parasite Trypanosoma brucei, the causative agent of human African sleeping sickness, all mRNAs are trans-spliced to generate a common 5′ exon derived from the spliced leader (SL) RNA.
Uthman Okalang +11 more
doaj +1 more source
t-loops at trypanosome telomeres [PDF]
The EMBO Journal, 2001 Mammalian telomeres form large duplex loops (t-loops) that may sequester chromosome ends by invasion of the 3′ TTAGGG overhang into the duplex TTAGGG repeat array. Here we document t-loops in Trypanosoma brucei, a kinetoplastid protozoan with abundant telomeres due to the presence of many minichromosomes.
George A. M. Cross +3 more
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Metatranscriptomic analyses of honey bee colonies
Frontiers in Genetics, 2015 Honey bees face numerous biotic threats from viruses to bacteria, fungi, protists, and mites. Here we describe a thorough analysis of microbes harbored by worker honey bees collected from field colonies in geographically distinct regions of Turkey ...
Cansu Ozge Tozkar +4 more
doaj +1 more source
Through the dark continent: African trypanosome development in the tsetse fly [PDF]
, 2013 African trypanosomes are unicellular flagellated parasites causing trypanosomiases in Africa, a group of severe diseases also known as sleeping sickness in human and nagana in cattle.
Rotureau, Brice, Van Den Abbeele, Jan
core +4 more sources
Trypanosome Glycosylphosphatidylinositol Biosynthesis [PDF]
The Korean Journal of Parasitology, 2009 Trypanosoma brucei, a protozoan parasite, causes sleeping sickness in humans and Nagana disease in domestic animals in central Africa. The trypanosome surface is extensively covered by glycosylphosphatidylinositol (GPI)-anchored proteins known as variant surface glycoproteins and procyclins.
Yeonchul Hong, Taroh Kinoshita
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Memorias do Instituto Oswaldo Cruz, 2008 The biology, epidemiology, pathogenesis, diagnostic techniques, and history of the introduction of Trypanosoma (Duttonella) vivax in the New World are reviewed.
Ana Luiza Alves Rosa Osório +5 more
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Green fluorescent diamidines as diagnostic probes for trypanosomes [PDF]
, 2014 LED fluorescence microscopy offers potential benefits to the diagnosis of human African trypanosomiasis, as well as to other aspects of diseases management, such as detection of drug resistant strains.
Arvind Kumar +27 more
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