Results 251 to 260 of about 712,349 (416)

L-asparaginase is a PAR2 N-terminal protease that unmasks the PAR2 tethered ligand. [PDF]

Cell Death Discov
Lee JK, Riabowol K, Wang X, Lee KY.
europepmc   +1 more source

FGF2 Mediated USP42‐PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

Advanced Science, EarlyView.
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang, Qiang Tian, Zhenli Lei, Shuxin Wang, Nan Cheng, Zhen Wang, Xianqin Jiang, Xuqun Zheng, Wenjing Xu, Minyan Ye, Longwei Zhao, Meiyun Wen, Jianlou Niu, Weijian Sun, Pingping Shen, Zhifeng Huang, Xiaokun Li   +16 more
wiley   +1 more source

Angiotensinogen and C3 compete for renin-induced complement activation. [PDF]

Front Immunol
Kristoffersson AC, Sköld A, Welinder C, Wendler M, Kalliokoski G, Bekassy Z, Karpman D.   +6 more
europepmc   +1 more source

CRYSTALLINE CHYMO-TRYPSIN AND CHYMO-TRYPSINOGEN [PDF]

, 1935
M. Kunitz, John H. Northrop
openalex   +1 more source

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

Advanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li, Zhuowen Hao, Fangzi Ke, Zhihui Liu, Weilong Wang, Sihui Wen, Fan Wu, Bowen Xu, Miao He, Shengyu Zou, Xiong Chen, Jingfeng Li, Zuhong He   +12 more
wiley   +1 more source

Evaluation of Canine Erythrocyte Surface Antigens and Morphological Alterations Induced by Trypsin Treatment. [PDF]

Animals (Basel)
Geum YJ, Han HJ.
europepmc   +1 more source

THE EQUILIBRIUM BETWEEN ACTIVE NATIVE TRYPSIN AND INACTIVE DENATURED TRYPSIN [PDF]

, 1934
M. L. Anson, A. E. Mirsky
openalex   +1 more source

A Single Point Mutation Creating a Furin Cleavage Site in the Spike Protein Renders Porcine Epidemic Diarrhea Coronavirus Trypsin Independent for Cell Entry and Fusion

Journal of Virology, 2015
Wentao Li, Oliver Wicht, F. V. van Kuppeveld, Qigai He, P. Rottier, B. Bosch   +5 more
semanticscholar   +1 more source

Genome‐Wide Silencer Screening Reveals Key Silencer Modulating Reprogramming Efficiency in Mouse Induced Pluripotent Stem Cells

Advanced Science, EarlyView.
This study utilized Ss‐STARR‐seq to construct a genome‐wide silencer map of mouse cells and elucidated the fundamental characteristics of these silencers. These silencers exist in a cell‐specific manner and exhibit unique epigenetic modifications. Through functional experiments, we also discovered that these silencers can regulate gene expression and ...
Xiusheng Zhu, Lei Huang, Guoli Li, Biao Deng, Xiaoxiao Wang, Hu Yang, Yuanyuan Zhang, Qiuhan Wen, Chao Wang, Jingshu Zhang, Yunxiang Zhao, Kui Li, Yuwen Liu   +12 more
wiley   +1 more source

The structure of the Gemella haemolysans M26 IgA1 protease trypsin-like domain. [PDF]

Acta Crystallogr F Struct Biol Commun
Tran N, Redzic JS, Eisenmesser EZ, Holyoak T.   +3 more
europepmc   +1 more source