Results 91 to 100 of about 3,225,670 (405)

A Simple, Quantitative Method for Titration of Trypsin and Trypsin Inhibitors.

open access: yesExperimental Biology and Medicine, 1949
SummaryA technically simple, rapid method for the quantitative titration of trypsin or similar proteolytic enzymes, and of protease inhibitors, suitable for critical tests on a large scale is described. The procedure utilizes technics familiar to serologists, rather than to skilled biochemists only, and gives definitive, reproducible results that can ...
Rosemary P. Mudd, Kenneth L. Burdon
openaire   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

MOLECULAR PROFILE, PURITY AND PRESENCE OF TRYPSIN INHIBITORS IN COWPEA PROTEIN ISOLATES

open access: yesRevista Caatinga, 2018
The most-used preparation process of protein isolates (PI) involves the isoelectric precipitation of the protein. Heating shortens the preparation time but this procedure may affect the purity, yield, molecular profile of the protein, and the activity of
KAROLINE DE MACÊDO GONÇALVES FROTA   +3 more
doaj   +1 more source

Use of microwaves to improve nutritional value of soybeans for future space inhabitants [PDF]

open access: yes
Whole soybeans from four different varieties at different moisture contents were microwaved for varying times to determine the conditions for maximum destruction of trypsin inhibitor and lipoxygenase activities, and optimal growth of chicks.
Singh, G.
core   +1 more source

Structural prediction and in silico physicochemical characterization for mouse caltrin I and bovine caltrin proteins [PDF]

open access: yes, 2016
It is known that caltrin (calcium transport inhibitor) protein binds to sperm cells during ejaculation and inhibits extracellular Ca2+ uptake. Although the sequence and some biological features of mouse caltrin I and bovine caltrin are known, their ...
Coronel, Carlos Enrique   +2 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

EFFECTIVENESS INACTIVATION OF TRYPSIN INHIBITOR FROM BRAZILIAN CULTIVARS OF BEANS (PHASEOLUS VULGARIS L.)

open access: yesAlimentos e Nutrição, 2011
The trypsin inhibitor, an antinutritional factor, which is abundant in dycotiledoneous and monocotyledoneous, is usually inactivated by heating treatment.
Kelli Cristina PAIVA   +2 more
doaj  

Effect of isolation conditions on structural properties and surface behavior of soy-whey proteins [PDF]

open access: yes, 2018
In this study, the impact of isolation conditions on structural and surface properties at the air/water interface of soy-whey proteins (SWP) was assessed. SWP were obtained by precipitation of soy-whey (at pH 4.5 or 8.0) with acetone or ammonium sulfate.
Ingrassia, Romina   +4 more
core   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

Methods and procedures for reducing soy trypsin inhibitor activity by means of heat treatment combined with chemical methods

open access: yesActa Universitatis Sapientiae: Alimentaria, 2018
We have developed a new procedure for reducing soy trypsin inhibitor activity by means of heat treatment combined with chemical methods, through which soy trypsin inhibitor activity decreases to the tenth or twentieth part of the original value.
Csapó J., Albert Cs.
doaj   +1 more source

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