Results 61 to 70 of about 353,545 (343)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Characterisation of serine proteinase inhibitors in dry seeds of cultivated pasture grass species : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Plant Biology and Biotechnology at Massey University, Palmerston North, New Zealand [PDF]

, 1994
Content removed due to copyright restriction: Tasneem, M., Cornford, C. A., & McManus, M. T. (1994). Characterization of serine proteinase inhibitors in dry seeds of cultivated pasture grass species. Seed Science Research, 4(3), 335-345.
Tasneem, Mohammad
core  

Organization and sequence of the gene encoding the human acrosin-trypsin inhibitor (HUSI-II) [PDF]

, 1993
A complete cDNA encoding the acrosin-trypsin inhibitor, HUSI-II, was used as a probe to isolate genomic clones from a human placenta library. Three clones which cover the entire HUSI-II gene were isolated and characterized.
Abelson, Baumann, Beato, Bird, Dynan, Fink, Fink, Greene, Greene, Haendle, Hehlein-Fink, Horii, Kazal, Laskowski, Laskowski, LaThangue, Luerssen, Mead, Moritz, Policastro, Reynolds, Sambrook, Scott, Stein, Strähle, Stühmer, Tan, Tora, Weih   +28 more
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Primary structure of potato Kunitz-type serine proteinase inhibitor [PDF]

, 2000
The serine proteinase inhibitor (PSPI-51) isolated from potato tubers (Solanum tuberosum L,) comprises two protein species with pi 5.2 and 6.3, denoted as PSPI-21-5.2 and PSPI-21-6.3, respectively.
Mentele, Reinhard, Mosolov, Vladimir V., Revina, Tatyana A., Valueva, Tatyana A.   +3 more
core   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Inhibitory effect of various recombinant corn trypsin inhibitor variants against trypsin

Zanco Journal of Medical Sciences
Background and objective: Trypsin is best known for playing a role in enteric digestion, among the most commonly examined serine proteases. Trypsin is expressed extra-pancreatically by a number of cancer types (for instance, Ovarian cancer), and it is ...
Badraldin Kareem Hamad
doaj   +1 more source

Streptomyces lavendulae Protease Inhibitor: Purification, Gene Overexpression, and 3-Dimensional Structure

Journal of Chemistry, 2015
Protease inhibitors trypsin (STI1, Streptomyces trypsin inhibitor 1) has been identified, purified by ammonium sulfate precipitation and Sephadex G-100 gel filtration. SDS-PAGE of protease inhibitor showed molecular weight of approximately 10 KDa.
D. E. El-Hadedy, El-Sayed E. Mostafa, Moataza M. Saad   +2 more
doaj   +1 more source

A trypsin-like serine protease is involved in pseudorabies virus invasion through the basement membrane barrier of porcine nasal respiratory mucosa

Veterinary Research, 2011
Several alphaherpesviruses breach the basement membrane during mucosal invasion. In the present study, the role of proteases in this process was examined.
Glorieux Sarah, Favoreel Herman W, Steukers Lennert, Vandekerckhove Annelies P, Nauwynck Hans J   +4 more
doaj   +1 more source

Chorionic Structures in Maternal Blood [PDF]

, 2007
Chorionic villi are the exchange structures of the placenta where human fetuses receive oxygen and nutrients from maternal blood, this article reports an improvement of a published method to recover them from the blood of pregnant, women, quotes their ...
Nilo Pereira Luz
core   +1 more source