Results 51 to 60 of about 3,419,991 (153)

Mitigation of antinutritional factors and protease inhibitors of defatted winged bean-seed proteins using thermal and hydrothermal treatments: Denaturation/unfolding coupled hydrolysis mechanism

Current Research in Food Science, 2022
The inactivation of antinutritional factors, protease inhibitors within winged bean protein was induced by two respective method treatments. The physical method based on steam vapor that was conducted using an autoclave and chemical method consisting on ...
Sami Saadi, Nazamid Saari, Hasanah Mohd Ghazali, Mohammed Sabo Abdulkarim   +3 more
doaj   +1 more source

The Effect of TiO2-Nanoparticle on the Activity and Stability of Trypsin in Aqueous Medium [PDF]

Journal of Nanostructures, 2018
Trypsin (E.C.3.4.21.4) is a serine protease commonly used in proteomics for digestion of proteins. In the present study, the effect of nano-TiO2 on the conformation and catalytic activity of trypsin were studied.
sakineh sadeghi kaji, behzad shareghi, Ayeh Bolouki, Masoud Salavati-Niasari   +3 more
doaj   +1 more source

Optimization of Solid-State Fermentation with Lactobacillus brevis and Aspergillus oryzae for Trypsin Inhibitor Degradation in Soybean Meal

, 2013
The aim of the present study was to optimize trypsin inhibitor degradation in soybean meal by solid-state fermentation (SSF) with Lactobacillus brevis and Aspergillus oryzae , and to determine the effect of SSF on phytic acid, crude protein, crude fat ...
You-ling Gao, Caisheng Wang, Qiu-hua Zhu, Guoying Qian   +3 more
semanticscholar   +1 more source

Structural Basis of Trypsin Inhibition and Entomotoxicity of Cospin, Serine Protease Inhibitor Involved in Defense of Coprinopsis cinerea Fruiting Bodies*

Journal of Biological Chemistry, 2011
Background: Mushrooms are a rich source of novel proteins with unique features. Results: Cospin, a trypsin-specific protease inhibitor, has a β-trefoil fold and is toxic against the fruit fly.
J. Sabotič, S. Bleuler-Martinez, M. Renko, Petra Avanzo Caglič, S. Kallert, B. Štrukelj, D. Turk, M. Aebi, J. Kos, M. Künzler   +9 more
semanticscholar   +1 more source

Characterization and pharmacological properties of a novel multifunctional Kunitz inhibitor from Erythrina velutina seeds.

PLoS ONE, 2013
Inhibitors of peptidases isolated from leguminous seeds have been studied for their pharmacological properties. The present study focused on purification, biochemical characterization and anti-inflammatory and anticoagulant evaluation of a novel Kunitz ...
Richele J A Machado, Norberto K V Monteiro, Ludovico Migliolo, Osmar N Silva, Michele F S Pinto, Adeliana S Oliveira, Octávio L Franco, Sumika Kiyota, Marcelo P Bemquerer, Adriana F Uchoa, Ana H A Morais, Elizeu A Santos   +11 more
doaj   +1 more source

Hydrolyzation of duck meat protein using Bacillus cereus TD5B protease, pepsin, trypsin and their potency as an angiotensin converting enzyme inhibitor

Journal of the Indonesian Tropical Animal Agriculture, 2019
This study was aimed to explore their potency of protein-bioactive of native ducks-meat after enzymatic hydrolysis by Bacillus-cereus TD5B-protease, Pepsin, and Trypsin as an angiotensin-converting enzyme (ACE) inhibitor. The samples: ducks-meats from 10
A. Winarti, F. Rahmawati, N. A. Fitriyanto, J. Jamhari, Y. Erwanto   +4 more
doaj   +1 more source

Trypsin inhibition by ferrocene [PDF]

Acta Periodica Technologica, 2005
Many transition metals and their complexes show inhibitory effect on someproteolytic enzymes, including trypsin. Their inhibitory activity is based on the direct binding to the active site of trypsin, mimicking formation of a five-coordinate transition ...
Kukrić Zoran Z., Žabić Mirjana M.
doaj   +1 more source

Tumor-associated Trypsin Inhibitor [PDF]

Clinical Chemistry, 2002
AbstractTumor-associated trypsin inhibitor (TATI) is a low-molecular-weight (6 kDa) trypsin inhibitor that has been used as a marker for ovarian cancer. It is also expressed together with tumor-associated trypsin by many other tumors, and increased serum concentrations of TATI occur in connection with these.
openaire   +2 more sources

A new lysine derived glyoxal inhibitor of trypsin, its properties and utilization for studying the stabilization of tetrahedral adducts by trypsin

Biochemistry and Biophysics Reports, 2016
New trypsin inhibitors Z-Lys-COCHO and Z-Lys-H have been synthesised. Ki values for Z-Lys-COCHO, Z-Lys-COOH, Z-Lys-H and Z-Arg-COOH have been determined. The glyoxal group (–COCHO) of Z-Lys-COCHO increases binding ~300 fold compared to Z-Lys-H.
Jennifer A. Cleary, J. Paul G. Malthouse
doaj   +1 more source

Melanoidin as a Novel Trypsin Inhibitor

Bioscience, Biotechnology, and Biochemistry, 1994
Melanoidin, which was obtained by the Maillard reaction between D-glucose and glycine, was found to exert a potent inhibitory effect on the activity of trypsin with BANA as a synthetic substrate. The concentration of melanoidin required to reduce the activity of trypsin by 50% was less than 1 μg/ml, similar to that of soybean trypsin inhibitor and ...
Hirano, Miyuki, Miura, Masayo, Gomyo, Toshiharu   +2 more
openaire   +1 more source