Results 41 to 50 of about 242,155 (315)

Inter-α-Inhibitor Impairs TSG-6-Induced Hyaluronan Cross-Linking [PDF]

, 2013
Under inflammatory conditions and in the matrix of the cumulus-oocyte complex (COC), the polysaccharide hyaluronan (HA) becomes decorated covalently with heavy chains (HCs) of the serum glycoprotein inter-α-inhibitor (IαI).
Briggs, David C., Richter, Ralf P., Day, Anthony J., Ralf P. Richter, Baranova, Natalia, Viranga Tilakaratna, Day, Anthony J.; id_orcid, David C. Briggs, Natalia S. Baranova, Tilakaratna, Viranga, Enghild, Jan J., Caroline M. Milner, Baranova, Natalia S., Jan J. Enghild, Milner, Caroline M., Foulcer, Simon J., Simon J. Foulcer, Anthony J. Day   +17 more
core   +1 more source

Genetic variability for cyanogen and trypsin inhibitor contents in sorghum (Sorghum bicolor (L.) Moench)

Electronic Journal of Plant Breeding, 2016
Sorghum is a staple food in the arid and semi-arid tropics, and is an important animal and bird feed in some developed countries. Very limited reports are available on anti-nutritional factors in sorghum. Grains of 200 sorghum genotypes including adapted
Hariprasanna K., V. Agte, M. Elangovan, S. Gite and, A. Kishore   +4 more
doaj   +1 more source

Effect of thermally untreated soybean with low levels of Kunitz trypsin inhibitors in the diet of broilers [PDF]

Agroznanje, 2011
This paper researched the effect of raw Kunitz free trypsin inhibitor soybean sort "Lana" to the production characteristics of broilers (Ross 308), compared to raw soybeans with a standard level of trypsin inhibitors. The production results indicate that
Beuković Dejan, Ljubojević D., Beuković Miloš, Đorđević Nenad, Milošević Niko, Stanaćev Vidica   +5 more
doaj  

Avaliação biológica de linhagem de soja com baixa atividade de inibidores de tripsina Biological evaluation of soybean line with low trypsin inhibitor activities

Revista Brasileira de Zootecnia, 2000
Cultivar de soja BR 36 com atividades de inibidores de tripsina convencional e linhagem de soja BRM 95-5262 geneticamente modificadas para conter baixas atividades de inibidores de tripsina foram utilizados em ensaios biológicos com aves contendo 40 e 20%
Edna Mayumi Yuahasi Miura, Marco Aurélio R. Binotti, Daliane Souza de Camargo, Ivone Yurika Mizubuti, Elza Iouko Ida   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Combinatorial optimization of cystine-knot peptides towards high-affinity inhibitors of human matriptase-1. [PDF]

PLoS ONE, 2013
Cystine-knot miniproteins define a class of bioactive molecules with several thousand natural members. Their eponymous motif comprises a rigid structured core formed by six disulfide-connected cysteine residues, which accounts for its exceptional ...
Bernhard Glotzbach, Michael Reinwarth, Niklas Weber, Sebastian Fabritz, Michael Tomaszowski, Heiko Fittler, Andreas Christmann, Olga Avrutina, Harald Kolmar   +8 more
doaj   +1 more source

Mitigation of antinutritional factors and protease inhibitors of defatted winged bean-seed proteins using thermal and hydrothermal treatments: Denaturation/unfolding coupled hydrolysis mechanism

Current Research in Food Science, 2022
The inactivation of antinutritional factors, protease inhibitors within winged bean protein was induced by two respective method treatments. The physical method based on steam vapor that was conducted using an autoclave and chemical method consisting on ...
Sami Saadi, Nazamid Saari, Hasanah Mohd Ghazali, Mohammed Sabo Abdulkarim   +3 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The Effect of TiO2-Nanoparticle on the Activity and Stability of Trypsin in Aqueous Medium [PDF]

Journal of Nanostructures, 2018
Trypsin (E.C.3.4.21.4) is a serine protease commonly used in proteomics for digestion of proteins. In the present study, the effect of nano-TiO2 on the conformation and catalytic activity of trypsin were studied.
sakineh sadeghi kaji, behzad shareghi, Ayeh Bolouki, Masoud Salavati-Niasari   +3 more
doaj   +1 more source