Results 51 to 60 of about 261,497 (358)

Fluorescence-based proteasome activity profiling [PDF]

open access: yes, 2012
With the proteasome emerging as a therapeutic target for cancer treatment, accurate tools for monitoring proteasome (inhibitor) activity are in demand.
Berkers, C.R.   +4 more
core   +1 more source

Cinética de inativação de inibidores de tripsina e de insolubilização de proteínas de diferentes cultivares de soja Inactivation kinetics of low activity trypsin inhibitors and protein insolubilization of different soybean cultivars

open access: yesRevista Brasileira de Zootecnia, 2005
A soja (Glycine max (L.) Merrill) é uma das leguminosas mais estudadas, em virtude de sua intensa utilização como fonte de óleo comestível e proteína para alimentação humana e animal.
Edna Mayumi Yuahasi Miura   +3 more
doaj   +1 more source

Fusion assays for screening of fusion inhibitors targeting SARS-CoV-2 entry and syncytia formation

open access: yesFrontiers in Pharmacology, 2022
Virus fusion process is evolutionarily conserved and provides a promising pan-viral target. Cell-cell fusion leads to syncytial formation and has implications in pathogenesis, virus spread and immune evasion.
Shiu-Wan Chan
doaj   +1 more source

Trypsin Inhibitor in Guar Meal

open access: yesExperimental Biology and Medicine, 1966
SummaryThe presence of trypsin inhibitor in Guar meal has been demonstrated by the trypsin-hemoglobin digestion procedure. The level of inhibition is concentration dependent. The inhibitor is destroyed by heating and is apparently not dialyzable, which may be indicative of a macromolecular nature.
C. R. Creger, Y. K. Bakshi, J. R. Couch
openaire   +3 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

The hydrolysis of N-benzoyl-L-argininamide by crystalline trypsin [PDF]

open access: yes, 1949
A reinvestigation of the kinetics of hydrolysis of N-benzoyl-n-argininamide by crystalline trypsin has led to the conclusion that the hydrolysis products enter into the over-all reaction as ...
Harmon, Kent M., Niemann, Carl
core  

Nutritional and Defensive Chemistry of Three North American Ash Species: Possible Roles in Host Performance and Preference by Emerald Ash Borer Adults [PDF]

open access: yes, 2018
Black ash (Fraxinus nigra), green ash (F. pennsylvanica), and white ash (F. americana) are the three most abundant ash species in the northeastern USA.
Chen, Yigen, Poland, Therese M
core   +3 more sources

Partial purification of trypsin inhibitors from Parkia seeds (Fabaceae)

open access: yesHoehnea, 2014
Leguminous seeds (Fabaceae) have a high content of inhibitors of which serine protease inhibitors are the most widely studied. However, there are only a few studies related to the investigation of these proteins in tree species belonging to the Amazon ...
Larissa Ramos Chevreuil   +5 more
doaj  

Novel Inhibitors and Activity-Based Probes Targeting Trypsin-Like Serine Proteases

open access: yesFrontiers in Chemistry, 2022
The trypsin-like proteases (TLPs) play widespread and diverse roles, in a host of physiological and pathological processes including clot dissolution, extracellular matrix remodelling, infection, angiogenesis, wound healing and tumour invasion/metastasis.
Timothy E. G. Ferguson   +3 more
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

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