Results 61 to 70 of about 8,341 (178)
Identification of Trypsinogen in the Lipotropic Fraction.
Experimental Biology and Medicine, 1953 SummaryThe postulation that the lipotropic fraction prepared by Bosshardt et al. (2) contained trypsinogen has been confirmed by a direct analysis. In view of this finding, it is no longer necessary to ascribe an additional new activity to enterokinase.
R J, PEANASKY, M, LASKOWSKI
openaire +2 more sources
Genetic aspects of chronic pancreatitis: insights into aetiopathogenesis and clinical implications
Swiss Medical Weekly, 2001 The recent genetic discoveries in CP support the hypothesis that inappropriate intrapancreatic activation of zymogens by trypsin results in autodigestion and pancreatitis.
K. Truninger +3 more
doaj +1 more source
Advanced Science, Volume 13, Issue 24, 27 April 2026.This study shows TGM2 is upregulated in AP, impairing macrophage efferocytosis by inhibiting the STAT6–GAS6 axis. The lactoferrin‐modified, ROS‐responsive LF‐LNP@si‐TGM2 targets pancreatic macrophages, silences TGM2, restores the axis, and alleviates AP.
Xuxu Liu +8 more
wiley +1 more source
Partially folded intermediates during trypsinogen denaturation
Brazilian Journal of Medical and Biological Research, 1999 The equilibrium unfolding of bovine trypsinogen was studied by circular dichroism, differential spectra and size exclusion HPLC. The change in free energy of denaturation was = 6.99 ± 1.40 kcal/mol for guanidine hydrochloride and = 6.37 ± 0.57 kcal/mol
Martins N.F., Santoro M.M.
doaj
Enterokinase Enhances Influenza A Virus Infection by Activating Trypsinogen in Human Cell Lines
Frontiers in Cellular and Infection Microbiology, 2018 Cleavage and activation of hemagglutinin (HA) by trypsin-like proteases in influenza A virus (IAV) are essential prerequisites for its successful infection and spread.
Hideki Hayashi +9 more
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Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT Recent refinements to diabetes classification frameworks have inadvertently complicated the diagnostic process, particularly in resource‐limited settings. This case demonstrates that meticulous phenotyping, judicious selection of feasible investigations, and disciplined clinical inference are essential to avoid misclassification and deliver ...
Issakwisa Mwakyula +2 more
wiley +1 more source
Pediatric Pulmonology, Volume 61, Issue 4, April 2026.ABSTRACT Objective This study aimed to evaluate 5‐year outcomes of a structured quality improvement (QI) program implemented as part of the standard of care at our CF center, focusing on changes in body mass index (BMI) and forced expiratory volume in 1 s (FEV₁) in pwCF followed at our institution.
S. Karabulut +14 more
wiley +1 more source
Interaction of protein C inhibitor with the type II transmembrane serine protease enteropeptidase.
PLoS ONE, 2012 The serine protease inhibitor protein C inhibitor (PCI) is expressed in many human tissues and exhibits broad protease reactivity. PCI binds glycosaminoglycans and certain phospholipids, which modulate its inhibitory activity.
Thomas A Prohaska +3 more
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Role of intrapancreatic SPINK1/Spink3 expression in the development of pancreatitis
Frontiers in Physiology, 2012 Studies on hereditary pancreatitis have provided evidence in favor of central role for trypsin activity in the disease. Identification of genetic variants of trypsinogen linked the protease to the onset of pancreatitis, and biochemical characterization ...
Masaki eOhmuraya +4 more
doaj +1 more source
Pancreatic gene expression during recovery after pancreatitis reveals unique transcriptome profiles
Scientific Reports, 2018 It is well known that pancreatic recovery after a single episode of injury such as an isolated bout of pancreatitis occurs rapidly. It is unclear, however, what changes are inflicted in such conditions to the molecular landscape of the pancreas.
Kristy Boggs +10 more
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