Results 221 to 230 of about 418,334 (279)

From a single C-mannose to multiple C-mannosyltransferases. [PDF]

J Biol Chem
Bakker H, Garbers C, Routier FH.
europepmc   +1 more source

Stafib‐2‐CR: an Improved Nanomolar and Selective Inhibitor of the Transcription Factor STAT5b Developed by Conformational Restriction of Stafib‐2

Chemistry – A European Journal, EarlyView.
Conformational restriction strategies to increase the activity and selectivity of the STAT5b inhibitor Stafib‐2 are presented. The best conformationally restricted inhibitor Stafib‐2‐CR has threefold higher activity against STAT5b than Stafib‐2. A cell‐permeable prodrug of Stafib‐2‐CR inhibits phosphorylation of STAT5b in cultured human leukemia cells ...
Theresa Münzel, Angela Berg, Christoph Protzel, Sylvie Schäfer, Alexander Jensen‐Feinhals, Thorsten Berg   +5 more
wiley   +1 more source

Systems biology insights into the molecular drivers of childhood stunting and implications for intervention. [PDF]

Front Nutr
Dable-Tupas G, Maraon ABA, Bernolo LJL, Toñacao NGF, Taylaran ADM, Plata MAC, Alcano JC, Björvang RD, Zain SM, Kobayashi V, Arefayine MB, Toni AT, Nacis JS, Gonzales GB.   +13 more
europepmc   +1 more source

Probing the Influence of Sulfur–Aromatic Interactions on the Electronic Structure of Gas‐Phase Peptides

Chemistry – A European Journal, EarlyView.
Just as fingerprints reveal identity, spectroscopic fingerprints reveal molecular secrets. In this article, we show parts of the unique fingerprint of the sulfur–aromatic interaction. By measuring how this force alters the electronic structure of gas‐phase peptides, we provide a fundamental understanding of interactions that give insights into the ...
Laura Pille, Carlos Ortiz‐Mahecha, Bart Oostenrijk, Juliette Leroux, Marion Girod, Konstantin Hirsch, Luke MacAleese, Robert Horst Meißner, Debora Scuderi, Isaak Unger, Vicente Zamudio‐Bayer, Sadia Bari, Lucas Schwob   +12 more
wiley   +1 more source

Living Microbial Drugs

Chemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

Targeting Tryptophan Metabolism for Tuberculosis Biomarkers and Host-Directed Therapy. [PDF]

J Infect Dis
Collins JM, Tukvadze N, Kempker RR.
europepmc   +1 more source

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

Chemistry – A European Journal, EarlyView.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Gold Nanocluster-Amino Acid Interactions: Assessment of DFTB with Dispersion Corrections. [PDF]

ACS Omega
Morehouse J, McPhee A, Howie E, L Oliveira LF.   +3 more
europepmc   +1 more source

The tryptophan-kynurenine pathway in cardiovascular diseases: mechanistic insights and therapeutic opportunities. [PDF]

Front Cardiovasc Med
Chen W, Shui M, Wei Z, Gao W, Liu X, Lei Q.   +5 more
europepmc   +1 more source

An Ecofriendly L-Tryptophan Containing UVA-1 Permissive Sunscreen Formulation: A Novel Approach for Inflammatory and Fibrosing Skin Diseases. [PDF]

Int J Tryptophan Res
Noakes R.
europepmc   +1 more source