Results 211 to 220 of about 418,334 (279)

Psychological distress links to magnetic resonance enterography abnormalities in Crohn's disease. [PDF]

Insights Imaging
Zhang R, Ke Y, Cai H, Wang Y, Huang L, Shen X, Zheng Q, Wu L, Zhao Q, Zheng W, Li D, Mao R, Li Z, Lin S, Li X, Peng Z.   +15 more
europepmc   +1 more source

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source

Gut microbial modulation of 3-hydroxyanthranilic acid and dopaminergic signalling influences attention in obesity. [PDF]

Gut
Castells-Nobau A, Fumagalli A, Del Castillo-Izquierdo Á, Rosell-Díaz M, de la Vega-Correa L, Samulėnaitė S, Motger-Albertí A, Arnoriaga-Rodríguez M, Garre-Olmo J, Puig J, Ramos R, Burokas A, Coll C, Zapata-Tona C, Perez-Brocal V, Ramio L, Moya A, Swann J, Martín-García E, Maldonado R, Fernández-Real JM, Mayneris-Perxachs J.   +21 more
europepmc   +1 more source

Image analysis method for measurement and prediction of intra‐matrix IgG diffusion

Biotechnology Progress, EarlyView.
Experimental and image analysis workflow for b‐IgG diffusion in hyaluronic acid (HA) matrix. Abstract Measurement and imaging of intra‐matrix protein therapeutics diffusion is important due to the emergence of injectable biologics currently in various stages of research and clinical testing.
Riya Debbarma, Antonio C. F. dos Santos, Michael Ladisch   +2 more
wiley   +1 more source

Melatonin ameliorates autistic-like behaviors by restoring gut microbiota-derived tryptophan metabolites. [PDF]

Cell Mol Life Sci
Shen J, Gao J, Gao L, Yan D, Wang Y, Meng J, Li H, Chen D, Wu J.   +8 more
europepmc   +1 more source

Protein hydrolysates in cell culture: Toward multi‐omics characterization

Biotechnology Progress, EarlyView.
While protein hydrolysates are widely used in cell culture applications, they remain undefined and variable products. Multi‐omic characterization evaluating composition and function can transition hydrolysates toward semi‐defined media components.
Michelle Combe, Brandon M. Wrage, Angel Varela‐Rohena, Stanislav Sokolenko   +3 more
wiley   +1 more source

Identification and characterization of tryptophan metabolism-related genes in carotid artery plaques. [PDF]

PLoS One
Jia X, Wang Z, Bai L, Wei J, Wang X, Song Z, Guo X, Jiang R, Zhang Q.   +8 more
europepmc   +1 more source

Structural and Functional Properties of Ingredient Composition in Kenkey Preparation: A Review

ChemFoodChem, EarlyView.
This review synthesizes three decades of research on kenkey, a fermented maize staple of West Africa. Examining the structural, functional, and nutritional properties that emerge from traditional fermentation and thermal processing, and identifying priorities for future research toward quality standardization and commercial development. ABSTRACT Kenkey,
Afia Sakyiwaa Amponsah
wiley   +1 more source

Comparative transcriptomics reveals genes commonly induced by distinct stressors in <i>Chlamydia</i>. [PDF]

Infect Immun
Haines R, Wan D, Zhong G, Fan H.
europepmc   +1 more source

Optimization of CEST MRI Reporter Protein Design Using Cation‐Pi Networks

Chemistry – A European Journal, EarlyView.
A novel engineering approach can produce reporter proteins for cell and viral therapy tracking with unique magnetic resonance imaging (MRI) signatures, detectable with chemical exchange saturation transfer (CEST). We discover how cation‐π interactions between amino acid groups can help us fine‐tune magnetic resonance properties for noninvasive ...
David E. Korenchan, Ethan J. French, Emerenziana Runco, Chetan B. Dhakan, Jinwu Yan, Hiroshi Nakashima, Michael T. McMahon, Assaf A. Gilad, Christian T. Farrar   +8 more
wiley   +1 more source