Results 191 to 200 of about 226,401 (254)

Multi-omics elucidates the regulatory mechanisms of tryptophan in gut health of weaned piglets. [PDF]

Anim Microbiome
Hou X, Fu Y, Jia Z, Hou L, Yin Y, Xu K.
europepmc   +1 more source

Metabolomic investigation of cisplatin‐induced acute kidney injury in paediatric cancer patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Cisplatin causes acute kidney injury (AKI) in approximately 46% of paediatric cancer patients who receive it. Serum creatinine (SCr) is a poor biomarker of cisplatin nephrotoxicity, because there is a delay between cisplatin infusion and SCr elevation.
Yong Jin Lim, Amy Thachil, Kelly McMahon, Ross T. Tsuyuki, S. Rod Rassekh, Lesley G. Mitchell, Prasad Devarajan, Cherry Mammen, Bruce C. Carleton, Geoffrey D. E. Cuvelier, Victor A. Lewis, Colin J. D. Ross, Alexandra P. Zorzi, Sylvain Baruchel, Raveena Ramphal, Eric Bouffet, Mathieu Lemaire, Tom D. Blydt‐Hansen, Brad L. Urquhart, The Applying Biomarkers to Minimize Long‐Term Effects of Childhood/Adolescent Cancer Treatment (ABLE) Research Study Group, Tom Blydt‐Hansen, Bruce C. Carleton, Geoff D. E. Cuvelier, Sunil Desai, Prasad Devarajan, Conrad Fernandez, Adam Fleming, Paul Gibson, Caroline Laverdiere, Victor Lewis, Mary L. McBride, Bruno Michon, Shahrad Rod Rassekh, Colin J. D. Ross, Christine Sabapathy, Kirk R. Schultz, Michael Zappitelli, Alexandra Zorzi   +37 more
wiley   +1 more source

The Metabolic Architecture of Glaucoma: A Unified Framework of Cofactor Failure and Kynurenine Dysregulation. [PDF]

Int J Mol Sci
Caikovska L, Veitners A, Lavrinovica D, Vanags J, Klavins K, Laganovska G, Zemitis A.   +6 more
europepmc   +1 more source

Impact of Agitation Power Input on Aspergillus oryzae Metabolism: Application of Multi‐Omics on an Industrial Enzyme Fermentation

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The agitation power input substantially impacts the oxygen transfer rate in aerobic fermentation processes. Furthermore, in a carbon‐limited process where the substrate feed rate is controlled by the concentration of dissolved oxygen, the power input will consequently govern the feed rate.
Mariana Albino, Jean‐Marie Mouillon, Gisela Nadal‐Rey, Carina L. Gargalo, Ulrich Krühne, Krist V. Gernaey, Mads O. Albæk   +6 more
wiley   +1 more source

Plasma kynurenine to tryptophan ratio and arginine as biomarkers associated with GOLD classification and predicting poor prognosis in patients with acute exacerbation of chronic obstructive pulmonary disease. [PDF]

Front Med (Lausanne)
Tian Y, Li X, He L, Cui S, Liu P, Wang W.   +5 more
europepmc   +1 more source

Hemopexin Purification From Human Cohn Fraction IV Paste and Its Biophysical Characterization and Functional Evaluation in Sickle Cell Disease Mice

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Hemopexin (Hpx) is an acute phase plasma protein that is responsible for sequestration and removal of cell‐free heme with very high affinity (Kd < 1 pM). Hpx expression in liver cells is induced following an inflammatory event such as severe hemolysis. Therefore, plasma Hpx has potential clinical relevance due to its' ability to bind free heme,
Shuwei Lu, Saini Setua, Mohd A. Khan, Aaradhya Bansal, Quintin O'Boyle, Pedro Cabrales, David C. Irwin, Paul W. Buehler, Andre F. Palmer   +8 more
wiley   +1 more source

Solution-state nuclear magnetic resonance studies of the <i>Salmonella typhimurium</i> tryptophan synthase complex. [PDF]

Biochem Biophys Rep
D'Amico RN, Mondal S, Winston DS, Boehr DD.   +3 more
europepmc   +1 more source

Gut microbial metabolites in colorectal cancer: dual roles in tumorigenesis, immune crosstalk, and therapeutic innovation. [PDF]

Front Cell Infect Microbiol
Jin Y, Zhu H, Fan J, Xu H.
europepmc   +1 more source

Integrated analysis of phytomelatonin and related indoleamine accumulation in germinated rice: Effects of cultivar, germination stage, and grain fraction. [PDF]

Food Chem X
Moongngarm A, Kaennok J, Moontree T, Loypimai P.   +3 more
europepmc   +1 more source

Mechanisms by which complex carbohydrates influence immune imbalance in COPD via the gut-lung axis: from colonic fermentation to pulmonary immune responses. [PDF]

Front Nutr
Chen G, Chen Y, Chu C, Zhu X.
europepmc   +1 more source