Results 241 to 250 of about 229,751 (309)

In Vivo Biosynthesis and Direct Incorporation of Non‐Canonical Amino Acids into Proteins

open access: yesChemBioChem, Accepted Article.
Autonomous cells are engineered biological systems capable of biosynthesising and directly incorporating non‐canonical amino acids (ncAAs) into proteins. These systems have the potential to extend the applicability of the genetic code to enable large‐scale fermentative production of proteins carrying ncAAs.
Ivana Drienovska   +2 more
wiley   +1 more source

Macromolecular High‐Affinity Binding Probed by Advanced Fluorescence Techniques

open access: yesChemBioChem, EarlyView.
For interacting biomolecules in solution, confocal fluorescence microscopy enables some very effective approaches to characterize intermolecular binding in complex sample environments and with small sample consumption. These approaches range from fluorescence‐based genetically encoded biosensors for use in living cells to the high controllability in ...
Alida Meyer   +2 more
wiley   +1 more source

Adaptive and metabolic convergence in rhizosphere and gut microbiomes. [PDF]

open access: yesMicrobiome
Ilyaskina D   +4 more
europepmc   +1 more source

Gold Nanoparticles Guided by Self‐Assembling Peptides: From Sequence to Superstructure

open access: yesChemBioChem, EarlyView.
Self‐assembling peptides act as versatile templates for gold nanoparticle (AuNP) synthesis. Their organization into discrete nanostructures or hydrogels enables control over AuNP morphology and assembly, offering new opportunities for functional nanomaterials.
Simone Adorinni, Silvia Marchesan
wiley   +1 more source

Bioactivity profiles of progressively ring‐fluorinated cyclohexyl motifs in the WKYMVm peptide as formylpeptide FPR2 agonists and in keto‐piperazines as anti‐trypanosome agents.

open access: yesChemBioChem, Accepted Article.
A series of all‐cis ring fluorinated cyclohexylalanines with progressively increasing levels of vicinal fluorines, as well as 4‐fluorophenylalanine and pentafluoroarylphenylalanine were introduced into the WKYMVm peptide in place of its tyrosine residue, for assays against the G‐protein coupled formylpeptide receptor, FPR2.
David O'Hagan   +6 more
wiley   +1 more source

Efficacy of Xiaokeqing granules and lifestyle intervention in treating prediabetes mellitus considering metabolomic biomarkers: A randomised controlled trial. [PDF]

open access: yesWorld J Diabetes
Zhao JD   +11 more
europepmc   +1 more source

Chemically Synthesized LRAD3‐D1 Interacts with N‐Terminal Domain of SARS‐CoV‐2 Spike Protein

open access: yesChemBioChem, EarlyView.
Chemical synthesis, calcium‐templated in‐vitro folding and competitive ELISA assay reveal that only domain 1 of the LRAD3 ectodomain interacts with the severe acute respiratory syndrome‐related corona virus 2 (SARS‐CoV‐2) spike NTD, while domains 2 and 3 do not, providing valuable insight into ACE2‐independent viral entry pathways that may contribute ...
Mrinmoy Jana   +5 more
wiley   +1 more source

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