Results 251 to 260 of about 436,973 (328)

Complementary immunoregulatory effects of <i>Bifidobacterium longum</i> 1714<sup>TM</sup> associated exopolysaccharide and tryptophan metabolism. [PDF]

open access: yesCurr Res Microb Sci
Groeger D   +14 more
europepmc   +1 more source

Organocatalytic Microfluidic Double‐Layer Capacitors

open access: yesAngewandte Chemie, EarlyView.
Highest expectations from catalysis with external electric fields, from organic synthesis to sustainable industrial production and the origin of life, cannot be explored because of the incompatibility with scalable bulk conditions. This challenge is addressed with bioinspired organocatalytic electrical double‐layer architectures as supramolecular ...
Shen‐Yi Guo   +7 more
wiley   +2 more sources

Unterschiedliche Reaktionen und Enzyme in der Psilocybin‐ Biosynthese bei Inocybe‐ und Psilocybe‐Pilzen

open access: yesAngewandte Chemie, EarlyView.
Pilze haben zweimal unabhängig gelernt, Psilocybin, den ikonischen Naturstoff der Zauberpilze, herzustellen. Dieser Artikel stellt die Enzyme des zweiten Biosyntheseweges vor, der in einem Risspilz gefunden wurde. Verblüffenderweise stimmen die beiden Wege in keiner Reaktion überein.
Tim Schäfer   +3 more
wiley   +1 more source

Modular Synthesis of Pyritide‐Inspired Macrocycles Featuring Bipyridine Motifs

open access: yesAngewandte Chemie, EarlyView.
A pyritide‐inspired build/couple/pair strategy yields a diverse macrocycle library. This approach expands chemical space and enables the discovery of 6paW, a potent anti‐ferroptotic agent. Abstract Macrocycles represent a promising class of drug‐like scaffolds with unique structural features and the ability to engage challenging targets such as protein–
Ji Hyae Lee   +4 more
wiley   +2 more sources

Unravelling the Functional Diversity of Type III Polyketide Synthases in Fungi

open access: yesAngewandte Chemie, EarlyView.
Type III polyketide synthases (T3PKSs) produce diverse compounds of ecological and clinical importance. Here, the activity of 37 fungal T3PKSs was profiled, revealing unexpected products and generating several pharmaceutical precursors. The machine learning model trained on the activity data accurately extrapolates the predictions to other enzymes and ...
Nika Sokolova   +3 more
wiley   +1 more source

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