Results 181 to 190 of about 1,437,430 (390)

Deciphering Tryptophan Oxygenation: Key Modulators of 2‐Oxindole Formation in MarE

open access: yesAngewandte Chemie International Edition, Accepted Article.
MarE, a heme‐dependent aromatic oxygenase with a histidyl axial ligated, catalyzes the monooxygention of β‐methyl‐L‐tryptophan, to form a 2‐oxindole scaffold central to maremycin biosynthesis. Although structurally similar to tryptophan 2,3‐dioxygenase (TDO), which initiates L‐tryptophan catabolism via dioxygenation, MarE exhibits distinct reactivity ...
Romie C. Nguyen, Inchul Shin, Aimin Liu
wiley   +1 more source

Genetic regulation of l-tryptophan metabolism in Psilocybe mexicana supports psilocybin biosynthesis

open access: yesFungal Biology and Biotechnology
Background Although Basidiomycota produce pharmaceutically and ecologically relevant natural products, knowledge of how they coordinate their primary and secondary metabolism is virtually non-existent.
Paula Sophie Seibold   +5 more
doaj   +1 more source

Dysrupted microbial tryptophan metabolism associates with SARS-CoV-2 acute inflammatory responses and long COVID

open access: yesGut Microbes
Protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and risk of long COVID has been associated with the depletion or over-abundance of specific taxa within the gut microbiome.
Lu Yao   +9 more
doaj   +1 more source

Analysis of plant metabolomics data using identification‐free approaches

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Plant metabolomes are structurally diverse. One of the most popular techniques for sampling this diversity is liquid chromatography–mass spectrometry (LC‐MS), which typically detects thousands of peaks from single organ extracts, many representing true metabolites.
Xinyu Yuan   +2 more
wiley   +1 more source

Tryptophan Metabolism in Humans with Various Types of Anemias [PDF]

open access: bronze, 1968
L. V. Hankes   +3 more
openalex   +1 more source

Dual Functions of Dietary Rubber Seed Oil Supplementation: Enriching N‐3 Polyunsaturated Fatty Acids and Enhancing Antioxidant Capacity in Pekin Ducks

open access: yesAnimal Research and One Health, EarlyView.
Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang   +10 more
wiley   +1 more source

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