Results 251 to 260 of about 1,437,430 (390)

Induction of pterin synthesis is not required for cytokine-stimulated tryptophan metabolism [PDF]

, 1993
Naoki Sakai, Kuniaki Saito, Seymour Kaufman, Melvyn P. Heyes, Sheldon Milstien   +4 more
openalex   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Epacadostat Overcomes Cetuximab Resistance in Colorectal Cancer by Targeting IDO-Mediated Tryptophan Metabolism. [PDF]

Cancer Sci
Zhou Y, Tao Q, Luo C, Chen J, Chen G, Sun J.   +5 more
europepmc   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Composite Probiotics Improve Gut Health and Enhance Tryptophan Metabolism in Nursery Piglets During Liquid Feeding. [PDF]

Int J Mol Sci
Du M, Zhang Q, Shen Y, Fu J, Wang Y, Yao B, Lu Z.   +6 more
europepmc   +1 more source

Effects of Dietary Pyrazinamide on the Metabolism of Tryptophan to Niacin in Streptozotocin-diabetic Rats [PDF]

, 1997
Katsumi Shibata, Aya Ishikawa, Takako Kondo   +2 more
openalex   +1 more source

The crosstalk between immune activation and metabolism in heart failure. A scientific statement of the Heart Failure Association of the ESC

European Journal of Heart Failure, EarlyView.
Abstract A better understanding of additional mechanisms of heart failure (HF) progression may allow a different and more complete phenotyping of the disease and identification of novel therapeutic targets. Persistent latent myocardial inflammation/immune activation in HF may represent an attempt to restore tissue homeostasis in the failing heart ...
Gabriele Fragasso, Davide Stolfo, Markus S. Anker, Antoni Bayes‐Genis, Ovidiu Chioncel, Stephane Heymans, Pardeep S. Jhund, Basil S. Lewis, Gary D. Lopaschuk, Lars H. Lund, Arantxa Gonzalez, Matteo Pagnesi, Gabriele Giacomo Schiattarella, Carlo Gabriele Tocchetti, Peter van der Meer, Sophie Van Linthout, Sven Wassmann, B. Daan Westenbrink, Marco Metra, Giuseppe M.C. Rosano, Gianluigi Savarese   +20 more
wiley   +1 more source

Nutrient-Synbiotic Complex Ameliorates LPS-Induced Depressive-Like Behavior via Modulation of Gut Microbiota and Tryptophan Metabolism in Mice. [PDF]

Food Sci Nutr
Liu Z, Shi S, Zhang X, Wu C, Yang Q, Ren S, Shan Y, Na G.   +7 more
europepmc   +1 more source

Influence of Adenine-induced Renal Failure on Tryptophan-niacin Metabolism in Rats [PDF]

, 2001
Tsutomu Fukuwatari, Yuko Morikawa, Fumiko Hayakawa, Etsuro Sugimoto, Katsumi Shibata   +4 more
openalex   +1 more source

Postulations for the Migration Behavior of Amino Acids as Cations in Capillary Zone Electrophoresis

ELECTROPHORESIS, EarlyView.
ABSTRACT Amino acids (AAs) in their cationic form at pH 2.2 and usual ionic strength show a non‐intuitive migration order in CZE. This is explained by setting up four postulates. The central points in these postulates are the influence of the AA side chain on the pKa${\rm p}K_{\rm a}$ value and the adoption of a defined, preferred conformation to build
Peter Gross, Tom Huber, Isabel Lunow, Dominik Burkhard, Holger Seelert, Rolf Müller   +5 more
wiley   +1 more source