Results 201 to 210 of about 70,579 (241)

Quinic acid alleviates high-fat diet-induced neuroinflammation by inhibiting DR3/IKK/NF-κB signaling via gut microbial tryptophan metabolites. [PDF]

Gut Microbes
Li S, Cai Y, Guan T, Zhang Y, Huang K, Zhang Z, Cao W, Guan X.   +7 more
europepmc   +1 more source

[Tryptophan, its metabolites and carcinogenesis].

Voprosy pitaniia, 1968
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Neurotoxicity of tryptophan metabolites

Biochemical Society Transactions, 2007
The metabolism of tryptophan by the kynurenine pathway leads to the production of several neurotoxic compounds, some of which have been associated with neurological disorders. Recent investigation of some relevant compounds in this pathway has provided further evidence of their neurotoxicity.
A J, Smith, T W, Stone, R A, Smith
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Chromatographic separation of tryptophan metabolites

Analytical Biochemistry, 1970
Abstract Separation of tryptophan and 15 metabolites by ion-exchange chromatography using Sephadex QAE-A25 and carboxymethyleellulose in a continuous system is reported. The system employs a complex NaCl gradient to elute the QAE-A25 column, and a simple linear NaCl gradient to elute the CMC column.
M, Bakri, J R, Carlson
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Tryptophan Metabolites and Brain Disorders

Clinical Chemistry and Laboratory Medicine, 2003
Tryptophan is metabolised primarily along the kynurenine pathway, of which two components are now known to have marked effects on neurons in the central nervous system. Quinolinic acid is an agonist at the population of glutamate receptors which are sensitive to N-methyl-D-aspartate (NMDA), and kynurenic acid is an antagonist at several glutamate ...
Trevor W, Stone, Gillian M, Mackay, Caroline M, Forrest, Catherine J, Clark, L Gail, Darlington   +4 more
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Tryptophan and indolic tryptophan metabolites in chronic renal failure

The American Journal of Clinical Nutrition, 1980
Tryptophan and indolic tryptophan metabolites were measured in the serum of normal subjects and chronic renal failure patients. The tryptophan free/total ratio was 0.07 in the normal serum, but the other tryptophan metabolite values were below detectable levels.
A, Saito, T, Niwa, K, Maeda, K, Kobayashi, Y, Yamamoto, K, Ohta   +5 more
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Kynurenine metabolites of tryptophan

Neurology, 1990
Over the past 2 decades, a number of studies have demonstrated that amino acids act as precursors for the biosynthesis of a variety of neuroactive compounds, including catecholamines and indoleamines. For example, the aromatic amino acid L-tryptophan is a precursor for serotonin biosynthesis.
A, Freese, K J, Swartz, M J, During, J B, Martin   +3 more
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Gas chromatographic analysis of tryptophan metabolites

Journal of Chromatography A, 1971
Abstract A procedure was developed for preparing the derivatives of tryptophan metabolites, which were classified into three groups; (A) kynurenine and its related compounds; (B) 2-aminoacetophenone and its related compounds; and (C) anthranilic acid and its related compounds.
T, Noguchi, H, Kaseda, N, Konishi, R, Kido   +3 more
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