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The Role of Tryptophan Metabolites in Musculoskeletal Stem Cell Aging
International Journal of Molecular Sciences, 2020 Although aging is considered a normal process, there are cellular and molecular changes that occur with aging that may be detrimental to health. Osteoporosis is one of the most common age-related degenerative diseases, and its progression correlates with
Wendy B Bollag +2 more
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Metabolites, 2021 The kynurenine pathway of tryptophan (TRP) degradation (KP) generates metabolites with effects on metabolism, immunity, and mental health. Endurance exercise training can change KP metabolites by changing the levels of KP enzymes in skeletal muscle. This
Paula Valente-Silva +2 more
exaly +2 more sources
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EXCRETION OF TRYPTOPHAN METABOLITES IN RHEUMATOID ARTHRITIS*
Annals of the New York Academy of Sciences, 1963AbstractThe excretion of 3 hydroxy anthranilic acid, a metabolite of trytophan, was studied in a group of patients with rheumatoid arthritis, the other connective tissue diseases, and hospital controls. Ten of 26 patients with rheumatoid arthritis, 3 of 18 with the collagen diseases, and only 1 of 26 hospital controls excreted more than 500 μg.
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Salicyluric Acid as a Metabolite of L-Tryptophan
Nature, 1965THE metabolites appearing in the urine after an oral load of L-tryptophan have been separated by paper, thin-layer and column chromatography. After ingestion of L-tryptophan (70 mg/kg body-wt.) the urine was collected at timed intervals over the next 24 h. Aliquots of the urine were examined by two-way paper chromatography (n-butanol–acetic acid–water,
W I, Austad, J R, Clamp, R G, Westall
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Gas chromatographic analysis of tryptophan metabolites
Journal of Chromatography A, 1971Abstract A procedure was developed for preparing the derivatives of tryptophan metabolites, which were classified into three groups; (A) kynurenine and its related compounds; (B) 2-aminoacetophenone and its related compounds; and (C) anthranilic acid and its related compounds.
T, Noguchi +3 more
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Tryptophan and Kynurenine Metabolites: Are They Related to Depression?
Neuropsychobiology, 2018<b><i>Background:</i></b> Some previous studies found decreased concentrations of L-tryptophan (TRY) and increased L-kynurenine (KYN), or its metabolites, in the body fluids of subjects with major depressive disorder (MDD), sometimes in association with suicidal behavior.
Pompili M. +13 more
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Tryptophan metabolites in hypoglycemia associated with neoplasia
Cancer, 1966Studies on tryptophan metabolites in the blood and urine of 5 additional patients having symptoms of hypoglycemia associated with neoplasia are reported. Three patients having islet cell tumors and hypoglycemia had normal levels of tryptophan metabolites in the blood and urine during hypoglycemia. A patient with metastatic carcinoma of the breast and a
M N, Silverstein, K G, Wakim, R C, Bahn
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Tryptophan metabolite excretion by the American cockroach
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1973Abstract 1. 1. Three fluorescing materials have been discovered in excreta from the American cockroach, Periplaneta americana (L.), and found to increase in concentration as dietary nitrogen increases. 2. 2. These compounds have been identified as kynurenic, xanthurenic and 8-hydroxyquinaldic acids. 3. 3.
D E, Mullins, D G, Cochran
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