Results 31 to 40 of about 22,323 (211)
Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis. [PDF]
, 2019 Chronic itch remains a highly prevalent disorder with limited treatment options. Most chronic itch diseases are thought to be driven by both the nervous and immune systems, but the fundamental molecular and cellular interactions that trigger the ...
Barton, Gregory M +11 more
core +1 more source
Thymic Stromal Lymphopoietin Isoforms, Inflammatory Disorders, and Cancer
Frontiers in Immunology, 2018 Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine originally isolated from a murine thymic stromal cell line. TSLP exerts its biological effects by binding to a high-affinity heteromeric complex composed of thymic stromal lymphopoietin ...
Gilda Varricchi +14 more
doaj +1 more source
MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation. [PDF]
, 2017 MicroRNAs (miRNAs) exert powerful effects on immunity through coordinate regulation of multiple target genes in a wide variety of cells. Type 2 innate lymphoid cells (ILC2s) are tissue sentinel mediators of allergic inflammation.
Ansel, K Mark +7 more
core +2 more sources
Mouse Models of Allergic Diseases: TSLP and Its Functional Roles
Allergology International, 2012 The cytokine TSLP was originally identified in a murine thymic stromal cell line as a lymphoid growth factor. After the discovery of TSLP, extensive molecular genetic analyses and gene targeting experiments have demonstrated that TSLP plays an essential ...
Miyuki Omori-Miyake, Steven F Ziegler
doaj +1 more source
Cellular Physiology and Biochemistry, 2015 Aims: Thymic stromal lymphopoietin (TSLP) plays an important role in inflammatory diseases and is over-expressed in human atherosclerotic artery specimens.
Jangchuan Dong +10 more
doaj +1 more source
Cells, 2021 Thymic stromal lymphopoietin (TSLP) is released by epithelial cells following disturbed homeostasis to act as “alarmin” and driver of Th2-immunity. Aberrant TSLP expression is a hallmark of atopic diseases, including atopic dermatitis (AD).
Magda Babina +3 more
doaj +1 more source
A Novel Non-invasive Method to Detect RELM Beta Transcript in Gut Barrier Related Changes During a Gastrointestinal Nematode Infection [PDF]
, 2019 Currently, methods for monitoring changes of gut barrier integrity and the associated immune response via non-invasive means are limited. Therefore, we aimed to develop a novel non-invasive technique to investigate immunological host responses ...
Affinass, Nicole +8 more
core +4 more sources
Role of the TSLP and its Receptor in the Treatment of Asthma
Barcelona Respiratory Network Reviews, 2023 Thymic stromal lymphopoietin (TSLP) is a crucial cytokine in initiating and regulating immune responses. Various cell types, including epithelial cells, fibroblasts, and dendritic cells, synthesize TSLP. TSLP activates dendritic cells, which subsequently
Miguel Estravís +2 more
doaj +1 more source
Thymic Stromal Lymphopoietin Induces Migration in Human Airway Smooth Muscle Cells [PDF]
, 2014 Airway remodeling due to increased airway smooth muscle (ASM) mass, likely due to enhanced migration and proliferation, has been shown to be highly associated with decline in lung function in asthma.
Gounni, Abdelilah S. +3 more
core +1 more source
Search for Compounds Regulating TSLP Production
YAKUGAKU ZASSHI, 2021 Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived immunostimulatory factor, which activates several immune cells such as dendritic cells, T cells, and mast cells. Recently, epithelial cell-derived TSLP has gained immense attention as a cytokine that induces allergic immune responses.
openaire +3 more sources