Results 21 to 30 of about 16,704 (236)
Intestinal bacteria induce TSLP to promote mutualistic T-cell responses [PDF]
, 2013 Thymic stromal lymphopoietin (TSLP) is constitutively expressed in the intestine and is known to regulate inflammation in models of colitis. We show that steady-state TSLP expression requires intestinal bacteria and has an important role in limiting the ...
Massacand, Jonathan +13 more
core +3 more sources
The influence of TSLP on the allergic response [PDF]
Mucosal Immunology, 2010 Exposure to allergens first occurs at body surfaces in direct contact with the environment such as the skin, airways, and gastrointestinal tract, and compelling evidence suggests that allergic inflammatory responses are profoundly influenced by the products of epithelial cells located at these sites.
M R, Comeau, S F, Ziegler
openaire +2 more sources
Characterization of the function of thymic stromal lymphopoietin in lymphopoiesis and lymph node organogenesis [PDF]
, 2010 Interleukin (IL)-7 is a cytokine, which is crucial for the development of the murine immune system. It is required for lymphopoiesis and for the development of peripheral lymph nodes (LN). IL-7-/-mice have impaired B and T cell lymphopoiesis, decreased
Chappaz, Stéphane
core +1 more source
Cellular & Molecular Immunology, 2008 Thymic stromal lymphopoietin (TSLP), an IL-7-related cytokine, is widely expressed by epithelial cells in many tissues with different biological effects. Human TSLP (hTSLP) has been shown to play an important role in promoting T cell homeostasis, developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic ...
Jiongkun, Wang, Feiyue, Xing
openaire +2 more sources
Role of thymic stromal lymphopoietin (TSLP) in asthma [PDF]
, 2021 Thymic Stromal Lymphopoietin (TSLP) is a pleiotropic cytokine originally isolated from a murine thymic stromal cell line and characterized as a lymphocyte growth factor. TSLP is predominantly expressed by lung and gut epithelial cells, keratinocytes, and
Criscuolo, Gjada
core +1 more source
The role of epithelial cells in atopy pathogenesis
Бюллетень сибирской медицины, 2019 Aim. The study of the mechanisms of atopic disease formation and a model of immunopathogenesis of the atopic diseases.Methods. Determination of surface lymphocytes receptors in peripheral blood of atopic bronchial asthma and atopic dermatitis patients ...
A. N. Kazimirsky +6 more
doaj +1 more source
Elevated Plasma Thymic Stromal Lymphopoietin After Acute Myocardial Infarction
Frontiers in Cardiovascular Medicine, 2022 BackgroundThymic stromal lymphopoietin (TSLP), a distant paralog of the cytokine IL-7, has been shown to be associated with atherosclerosis. However, the effect of plasma TSLP level after acute myocardial infarction (AMI) remains largely unclear.
Yuhao Zhao +7 more
doaj +1 more source
Exploration of Immunology, 2023 Aim: Atopic dermatitis (AD) is a pruritic, chronic inflammatory skin disease. Thymic stromal lymphopoietin (TSLP) is highly expressed in the epidermis of patients with AD and induces T helper 2 (Th2) immune responses and itching.
Masanori Fujii +7 more
doaj +1 more source
Journal of Immunology Research, 2020 Objectives. Both thymic stromal lymphopoietin (TSLP) and dendritic cells (DCs) are involved in many autoimmune diseases, but the potential roles of TSLP and DCs in bullous pemphigoid (BP) have not been clarified. We sought to explore the contributions of
Si-Zhe Li +4 more
doaj +1 more source
Cells, 2021 Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine highly expressed by epithelial cells and several innate and adaptive immune cells. TSLP exerts its biological effects by binding to a heterodimeric complex composed of TSLP receptor (TSLPR ...
Mariantonia Braile +8 more
doaj +1 more source